Ross Lifescience Pvt.Ltd.

• Developmental Toxicity Study – Rat & Rabbit
• Two Generation* Reproduction Toxicity study

• Bacterial Reverse Mutation Test (AMES Test)
• In-Vitro Mammalian Chromosome Aberration Test
• In- Vitro Mammalian Cell Gene Mutation Test
• In-vitro Mammalian Cell Micronucleus Test
• In-Vivo Mammalian Bone Marrow Chromosome Aberration Test
• Mammalian Spermatogonial Chromosome Abberation Test
• In-Vivo Mammalian Erythrocyte Micronucleus Test
• In- Vivo Un-Scheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells
• Mouse Heritable Translocation Assay
• Rodent Dominant Lethal Test

In agriculture practices, pests and diseases have a great economic significance, as per FAO estimates globally they contribute towards loses of about 20%-40% every year.

Use of Plant Protection Products is therefore very important as a failure in controlling the spread of plant pests and diseases can have disastrous consequences on agricultural production and food security.

But at the same time an improper & irrational use of such products can have serious implications on humans and animals who come in contact either directly or indirectly.

Therefore there are strict regulations for use of such products and companies manufacturing them are required to generate data to validate their efficacy and study if they are safe to use and at what levels. We at Ross, offer a variety of services as per our customers needs be it for in-house validation, development of new products or generating data as per regulatory requirements.

Rapid and successful registration of the active substances and products is the key to achieving economic success. We provide services in data generation for registrations of products as per contemporary regulatory guidelines. We have a GLP, NABL compliant facility. Also, we are an approved laboratory by Central Insecticides Board-India, for data generation as per Indian Regulatory requirements.

Through 10+ years of research and learning, Ross has developed expertise to provide guidance to our sponsors for various Regulatory requirements. We keep ourselves updated as per the contemporary regulatory guidelines and our experiments and reports are designed in such manner to fulfill the specific regulatory needs.

Registration of products with CIB

We provide registration services of pesticide products in India under various categories of The Insecticides Act 1968 for Import/ Indigenous manufacturing of technical material or formulations. It includes:

• Strategy and planning, performing data gap analysis
• Dossier preparation and submission
• Me-too registrations for indigenous manufacturing
• Export only applications
• Endorsements for label claims, packaging or other changes related to import source/manufacturer
• Data generation as per OECD guidelines for registration requirements outside India
• Quality Assurance compliance handling of misbranded samples

Registration of products with FDA

Registration of products (Drugs, cosmetics and disinfectants) under Drugs and Cosmetics Act. This includes:

• Data generation- Preclinical and Clinical toxicity studies
• Design and execution of Clinical trials
• Data collation, Dossier preparation and submission
• Obtaining registration

• Acute Oral – Rat
• Acute Dermal – Rat / Rabbit
• Acute Inhalation
• Primary Skin Irritation
• Acute Eye Irritation
• Skin Sensitization*

Ross offers end to end solution from product development to first experimental manufacturing run to deliver products that are tailor made to meet customer’s expectations

We act as a bridge between R&D and eventual commercialization of product.

We provide ideas that could be filtered through the innovation funnel which are then progressed through stage gate process with time bound deliverables

Ideation –> Development –> Manufacturing –> Launch

At Ross, we have a well-equipped state-of-the art laboratory for conducting development activity.Ross, being incubated by of Science and Technology Park promoted by NSTEDB, Dept. of Science & Technology, Govt. of India and University of Pune, has access to laboratories for conducting sophisticated experiments which includes access to SEM, high pressure reactors, pilot plants etc needed for product development.

In vivo Toxicity Testing Services

Toxicology Services

Pharmacology & Toxicology Services

Drug Discovery & Development Services

Agricultural Testing Services

Agriscience Services

Public Health Insecticide Services

• Indoor residual spray (IRS)- rural area
• Field trials of Liquid vaporizers, mosquito coil, vaporizing mats, ambient emanators and aerosols- WHO guidelines
• Instrument testing for applications
• Fogging trial (Thermal fogging & Ultra Low Volume fogging)- in laboratory and field
• Granular application for mosquito larvae control in Marshy areas
• Housefly control- bait development and efficacy and implementation
• Rodents control- bait development and efficacy and implementation

Veterinary services

Ecto/ endo parasites management by body application/ oral application as per customer requirements

Household Insecticide Services

We have state of the art laboratory for conducting experiments on pests of household importance like mosquitoes, cockroaches, bed bugs, housefly and termites. In the lab bred cultures, we have three species of mosquito, two deltamethrin resistant strains of mosquito, two species of cockroach, one species of house fly and one species of bedbugs. We undertake various in-house development projects like

• Efficacy and Potency determination of Bio larvicides like Bti
• Repellency testing using inter connected chambers
• Choice studies for crawling insects
• Direct spray knockdown studies

We also undertake projects for generation of data as per various regulatory requirements. We keep ourselves updated as per the contemporary regulatory guidelines and our experiments and reports are designed in such manner to fulfill the specific regulatory needs.

In vitro Toxicity Testing Services