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Rockland Immunochemicals, Inc.

4 Orders Completed
Limerick, Pennsylvania, US

About Rockland Immunochemicals, Inc.

Type: Privately Held

Established in 1962, Rockland Immunochemicals, Inc. is a global biotechnology company manufacturing leading edge research tools for basic, applied, and clinical research in functional genomics, gene therapy, and drug discovery markets. Rockland is a privately held company, operating a manufacturing facility with antibody and protein production capabilities located near Philadelphia, Pennsylvania, USA. Our laboratories consist of over 80,000 square feet, producing antibodies and antibody-based tools that are used to help define mechanisms underlying cell function and disease. European and Asian markets are supported through a highly specialized network of key distributors.

Our reputation is based on attention to detail, customer service, and continuous investment in the tools and technologies required to develop a world-class product line. We understand and appreciate how our products are helping solve significant global problems in life science research. We take great care to validate our products before they reach any research laboratory. Every lot of every product is quality-control tested to a rigorous standard and application-tested for consistent performance.

Certifications & Qualifications

OLAW USDA

Our Services (43)


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FANA Antisense Oligos (siRNA, shRNA, RNAi, CRISPR/Cas9 and transfection alternatives)

Price on request

Starting with a target nucleic acid molecule and the desired application for the intended antibody, Rockland’s scientists can design and conduct all the necessary steps for the generation of sequence specific or conformation specific ASO antibodies. Rockland has a demonstrated history of generating antibodies to ASO that exhibit high specificity and sensitivity. Antibodies can be developed as polyclonal, conventional monoclonal or recombinant monoclonal formats. The choice of clonality is dependent on client specific needs and timelines of the client.

For polyclonal antibodies (pAb) Rockland will recommend a host, immunization protocols and testing strategies to generate a volume of antiserum that satisfies the client’s reagent needs. Additionally, we perform downstream processing to purify antibody, enhance specificity by cross adsorption (if needed), and validate antibody performance by pre-determined criteria.

For conventional monoclonal antibody (mAb) and recombinant monoclonal antibodies (rAb), recommendations are made for generation of clonal cell lines or clonal selection, respectively, resulting in antibody reagents with the desired performance characteristics including sensitivity, specificity and affinity.


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Anti-Idiotype Antibody Production

Price on request

For more than twenty-five years, Rockland Immunochemicals, Inc. has produced customized anti-idiotype (anti-ID) antibodies for the detection, identification, and analysis of therapeutic drugs to support pre-clinical and downstream clinical trials. Anti-ID antibodies can be produced as polyclonal or hybridoma-based monoclonal antibodies depending on the needs of your study. These fit-for-purpose antibodies can be generated in a variety of hosts for use in studies to identify, neutralize, block, and assess the properties of drug to analyte binding on the target therapeutic antibody.


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Antibody Production

Price on request

Rockland’s versatile custom antibody services allow you to closely direct key processes used to generate your research antibody, intimately involving you in critical decision-making steps along the way. Let Rockland’s expertise aid you in the design and synthesis of your antigen of choice. We specialize in mammalian, bacterial, and insect cell-based recombinant protein expression and purification, thus ensuring production of high quality antigen suitable both for your immunization and screening regimen.

No matter whether your immunogen is protein, peptide, or oligo based, our antigen production platforms are completely scalable to deliver the quantities you need.

Multiple host species including mouse and rat, rabbits, goats, chickens, llamas, alpacas 

Chicken Hamster Mice Llama Alpaca Goat Rabbit Show 7 more tags Show less

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Host Cell Protein (HCP) Detection

Price on request

Rockland’s product portfolio provides well characterized and sensitive generic reagents for immunodetection of host cell proteins as well as multiple customizable options for process-specific HCP antibody development as a service. These options allow flexibility and control to the sponsor for developing early stage through late stage HCP detection reagents.

Rabbit Chicken Goat

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Custom Monoclonal Antibody (mAb) Production

Price on request

Rockland's monoclonal antibody development services allow generation of high quality and target specific antibodies. As a complete service, Rockland can design, synthesize, and conjugate peptides for use as immunogen for your monoclonal development program. Let Rockland’s expertise aid you in both the design and synthesis of antigenic peptides. 

Mice Hamster Rat

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Custom Polyclonal Antibody Production

Price on request

Rockland Immunochemicals has offered polyclonal antibody manufacturing services for more than four decades. Our expertise includes using a variety of different hosts for the development of polyclonal antibodies, including the most commonly used New Zealand white rabbits. Goats, sheep, guinea pigs, chickens, rats, mice and donkeys are also often selected.

Rabbit Goat Chicken Alpaca Llama

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Monoclonal Antibody (mAb) Production

Price on request

Rockland's monoclonal antibody development services allow generation of high quality and target specific antibodies. As a complete service, Rockland can design, synthesize, and conjugate peptides for use as immunogen for your monoclonal development program. Let Rockland’s expertise aid you in both the design and synthesis of antigenic peptides. 

Mouse Rat Hamster

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Antibody Purification

Price on request

Rockland offers a variety of purification services for the purification of native and recombinant proteins, as well as for antibodies (including fragments and modified proteins).

Native and recombinant protein purification can be carried out on materials that you supply or are generated by Rockland through our contract services. These proteins can also be further modified by chemical or enzymatic treatments (crosslinking, digestions, etc) and further purified if warranted.


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Cell and Tissue Culture

Price on request

With over 30 years of experience in culturing various cell lines for antibody and protein production, Rockland can produce cell culture material from both adherent and suspension lines. When performing cell culture work, cells are routinely produced in T-Flasks, roller bottles, and stir tanks. On the other hand, hollow fiber and CELLine flasks are used to enhance small-scale bio-production for antibody and protein generation. Other high capacity methods are also available if you're in need of large scale production requirements.


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Cryostorage and Cryoprocessing

Price on request

Cell storage for small and large cell banks can be provided on an annual basis.  Consider Rockland's robust cell storage facilities as a primary or secondary storage location for your most respected cell lines.  We urge you to protect your valuable research cell line by storage in multiple storage locations.


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Testing of Cell Lines

Price on request

Rockland can perform cell analysis, lysate production, mycoplasma, and sterility for Rockland- or client-produced cell lines.


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Cryopreservation

Price on request

Our team researches and creates both master and working cell banks specific to each client's individual requirements. Research cell banking is an inexpensive short term storage solution as a set number of vials (10 or 25) are produced, tested for viability, stored, and monitored in liquid nitrogen for 6 months. On the other hand, our master cell banking services uses a set number of vials from 10–200 and are produced, tested for viability, stored, and monitored in liquid nitrogen for two years. Cell line stability services can also be provided upon request.


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Cell Viability Assays

Price on request

Rockland can perform cell viability and cell proliferation studies for Rockland- or client-produced cell lines. Each assay provides a unique snapshot of cell health. When combined, these assays can form the basis for cell viability and overall health.


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Assay Development

Price on request

Rockland's full-service immunoassay development service bridges the path from discovery to product. Rockland's scientific expertise provides highly customized solutions to meet your basic, applied and clinical research demands in the development of unique in vitro assays.

To enable innovative biomarker development for drug discovery and diagnostic applications, we offer highly customized solutions. From the generation of highly specific antibodies to the development of unique in vitro assay systems, Rockland is your partner by providing scientific expertise for your biomarker evaluation and bioassay development needs. Our services include: Assay Development, Assay Qualification, Assay Validation, and Lot Release Testing and other related supporting services such as accelerated stability studies, antigen production and antibody development.


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Flow Cytometry

Price on request

The accuracy of Flow Cytometry analysis greatly depends on the use of suitable antibodies and optimized staining methods. Antibody titration and reactivity against the target antigen should be carefully determined and appropriate isotype controls should always be included in experimental designs. Rockland provides scientists with antibodies and supporting reagents tested and qualified for FC analysis including primary antibodies that recognize intracellular or cell surface cellular targets, secondary antibodies and isotype control proteins.


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Immunohistochemistry (IHC)

Price on request

Rockland's IHC Studies provide confidential high-quality target localization data through its extensive services. Researchers are presented with the option of outsourcing their entire IHC studies, bypassing the difficulties of sourcing and characterizing the appropriate target-specific antibodies or difficult-to-find validated tissues and the complex immunostain interpretation thereof. Commonly requested standardized IHC services are offered as Service Packets; however, Rockland’s custom design of your required study plan will address your particular biological questions. All studies are conducted under R&D conditions, are confidential and the results are proprietary to the customer.


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Biochemistry & Molecular Biology

Price on request

Molecular biology products and services represent an invaluable tool for the discovery and development of tools and products in the life sciences and medical field. Rockland’s growing suite of molecular biology custom products and services will help accelerate your studies whether working on basic research or performing advanced translational studies. By directly interacting with our molecular biology scientists at every step of the process, you gain flexibility and reliability during the experimental design and execution of your project.


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Protein Purification

Price on request

Native and recombinant proteins can be purified from various sources. Recombinant gene constructions can be generated and produced in the expression system of your choice.


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Nucleic Acid Services

Price on request

Purification and Isolation of Nucleic Acids 

Genomic DNA or mRNA is isolated from either frozen tissue or tissue culture cell preparations.

Genomic DNA isolation   
mRNA Isolation
cDNA Synthesis


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Biomarker Analysis

Price on request
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Western Blot

Price on request
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Bioconjugation/Chemical Crosslinking

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ELISA

Enzyme-linked immunosorbent assay
Price on request
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Custom Protein Production

Price on request
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Protein Quantification

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Cell Viability & Proliferation Assays

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Biology

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Antibody Services

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Protein Production

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Cell Lines

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Cell-Based Assays

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Biomarkers

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Protein Services

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RNA Services

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Cells and Tissues

Price on request
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Immunostaining

Price on request
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Protein Expression Visualization

Price on request
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Cytometry

Price on request
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Recombinant Protein Expression

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Flow Cytometry Data Analysis

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RNA Extraction and Purification

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Fluorescence Activated Cell Sorting (FACS)

Fluorescence Activated Cell Sorting
Price on request
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Immunocytochemistry

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DC

David Chimento

VP Client Solutions
BH

Brad Hobson

Sales Associate
DK

Dan Kenney

Director of Business Development
RM

Rockland Marketing

Marketing Manager
  • Positive review for Western Blot:

    February 2017

    "Rockland was great to work with - on-time delivery of deliverables and great communication throughout the process."

Rockland Immunochemicals, Inc. has not received any endorsements.