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Revolve Biotechnologies, Inc.

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Baltimore, Maryland, US

About Revolve Biotechnologies, Inc.

Revolve Biotechnologies is a life science company focused on engineering better biomolecules using novel directed evolution technologies.

Revolve offers custom DNA variant libraries and antibody discovery services. Our technology provides rapid access to comprehensive and expansive user-defined diversity,... Show more »

Revolve Biotechnologies is a life science company focused on engineering better biomolecules using novel directed evolution technologies.

Revolve offers custom DNA variant libraries and antibody discovery services. Our technology provides rapid access to comprehensive and expansive user-defined diversity, boosting the success rate of biopharmaceutical and enzyme optimization, protein variant discovery, and mutational mapping. Further applications include antibody/ADC/bispecific engineering, affinity maturation, and epitope mapping. The benefits of our novel patent-pending mutagenesis technology means a rapid delivery time at a highly cost-effective price.

The company’s IP portfolio was developed at and licensed from Johns Hopkins University. In addition to its internal protein pipeline, Revolve is currently offering a service for construction of custom DNA variant libraries with industry-leading performance and delivery time.

Selected Publications

  • Firnberg E, Labonte JW, Gray JJ, Ostermeier MA. A comprehensive, high-resolution map of a gene's fitness landscape, Molecular Biology and Evolution (2014)
  • Firnberg E, Ostermeier MA. PFunkel: efficient, expansive, user-defined mutagenesis, PLoS ONE (2012).
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Our Services (32)


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Ribosome Display

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Phage Display Library Construction and Screening

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Site-Directed Mutagenesis

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Antibody Discovery

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Drug Discovery & Development

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Site Saturation Mutagenesis

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Therapeutic Monoclonal Antibody (mAb) Development

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Antibody Services

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DNA Amplification

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ScFv Expression

Single Chain Variable Fragment Expression
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In vitro Monoclonal Antibody (mAb) Production

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Monoclonal Antibody (mAb) Production from Plasmids

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Monoclonal Antibody (mAb) Production from Synthetic Peptides

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Antibody Humanization

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Custom Monoclonal Antibody (mAb) Production

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Protein Engineering/Directed Evolution

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DNA Library Services

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Nucleic Acid Services

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Recombinant Antibody Production

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Phospho-Specific Antibody Production

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PCR

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Protein Purification

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Antibody Affinity Maturation

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Random Mutagenesis

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DNA Library Screening

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Monoclonal Antibody (mAb) Production

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Bioconjugation/Chemical Crosslinking

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DNA Services

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Protein Services

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Mutagenesis

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Protein Production

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Protein Expression Services

Protein Expression Services

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Alanine Scanning Mutagenesis

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