1343083028000

Reveal Biosciences

San Diego, California, US

Reveal Biosciences is a San Diego-based contract research organization (CRO) that specializes in Advanced Tissue Technologies. We are proud of our team of experienced scientists who are dedicated to providing high quality research solutions to our diverse range of clients. We have the flexibility to think outside the box and work with your specific needs. Contact us to find out how you can contain costs, meet timelines and achieve your preclinical research goals.

Reveal Biosciences has not listed any services.

Tumor Profiling
Price on request

From H&E stained tissue sections, we provide quantitation of percentage of tumor, stroma, necrosis, and inflammatory cells, as well as viable cell nuclei, using our ImageDx™ artificial intelligence platform. ImageDx uses sophisticated proprietary machine learning technology for reliable generation of quantitative data for your science.

From H&E stained tissue sections, we provide quantitation of percentage of tumor, stroma, necrosis, and inflammatory cells, as well as viable cell nuclei, using our ImageDx™ artificial intelligence platform. ImageDx uses sophisticated proprietary machine learning technology for reliable generation of quantitative data for your science.

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Human
Mouse
Rodents
Cancer
Oncology
FFPE tissue
Biology
Drug Discovery
Leica BOND-III
Colorectal cancer
Diseased human tissue
Breast cancer
Hematoxylin
Eosin
Lung Cancer
Ovarian Cancer
Pancreatic cancer
Machine learning
Fresh Tumors
FFPE
whole slide imaging
tissue section imaging
Multiplex Immunohistochemistry (mIHC)
Price on request

Our multiplex IHC service includes staining of paraffin (FFPE) or frozen tissue sections. Assay development and optimization using colorimetric, fluorescent and multiplex approaches are available. Optimization of your choice of antibody and detection system is also available on request.
Our state-of-the-art Leica Bond... Show more »

Our multiplex IHC service includes staining of paraffin (FFPE) or frozen tissue sections. Assay development and optimization using colorimetric, fluorescent and multiplex approaches are available. Optimization of your choice of antibody and detection system is also available on request.
Our state-of-the-art Leica Bond immunostainer produces consistent quality high throughput immunohistochemistry (IHC). We have developed and validated a wide range of automated IHC protocols for rodent and human tissue. Ask us about our validated protocols.

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Oncology
multiplex
FFPE tissue
Biology
Drug Discovery
immunohistochemistry
Triple-stain Immunohistochemistry
Dual-stain Immunohistochemistry
monoclonal antibodies
antibodies
PD-L1
FFPE
Toxicology
cd8
CD3
CD4
CD31
CD68
FOXP3
PD1
Ki67
pan-cytokeratin
Tissue Cross Reactivity Studies
Price on request

We test and optimize the experimental antibody in a single tissue, then test for cross-reactivity in a set number of other tissues, depending on the customer's needs.

We test and optimize the experimental antibody in a single tissue, then test for cross-reactivity in a set number of other tissues, depending on the customer's needs.

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RNAscope Assay
Price on request

We offer high quality singleplex and multiplex in situ hybridization (ISH) to localize mRNA in your tissue samples, using the two leading ISH technologies RNascope (ACD) and ViewRNA (Thermo Fisher Scientific). Custom probes can be provided on request, please contact us to discuss your needs.
Tissue preparation including wax... Show more »

We offer high quality singleplex and multiplex in situ hybridization (ISH) to localize mRNA in your tissue samples, using the two leading ISH technologies RNascope (ACD) and ViewRNA (Thermo Fisher Scientific). Custom probes can be provided on request, please contact us to discuss your needs.
Tissue preparation including wax processing, embedding and RNAse-free sectioning (microtomy), or frozen section preparation (cryotomy) are also available on request.
In addition, we offer digital slide scanning and image analysis, resulting in quantitative ISH data.

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Biology
Drug Discovery
FISH
mRNA
Fluorescence in situ Hybridization
Biomarker Assay Development
Price on request

Antibody selection and procurement services along with a full range of biomarker assay optimization levels for preclinical and clinical applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background. ... Show more »

Antibody selection and procurement services along with a full range of biomarker assay optimization levels for preclinical and clinical applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background. Immunohistochemistry and immunofluorescence available. Single-plex and multi-plex staining. Download "Reveal Biosciences Validated Biomarkers Feb 2018.pdf" in the resources for a list of our validated protocols.

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multiplex
immunohistochemistry
IHC
Dual-stain Immunohistochemistry
monoclonal antibodies
antibodies
Singlex
Antibody Testing
Price on request

Full range of antibody testing levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

Full range of antibody testing levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

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Immunofluorescence
immunohistochemistry
histology
IHC
AlexaFluor
Confocal Microscopy
Price on request

An optical imaging technique enabling the reconstruction of three-dimensional structures from the obtained images.

An optical imaging technique enabling the reconstruction of three-dimensional structures from the obtained images.

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Cancer
Biology
Drug Discovery
Leica BOND-III
Imaging & Spectroscopy
Price on request
Request a quote for more information about this service.
Cancer
Biology
Drug Discovery
Antibody Validation
Price on request

Full range of antibody optimization levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background. See our white paper "Reveal Biosciences Antibody Validation" in the resources for more details.

Full range of antibody optimization levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background. See our white paper "Reveal Biosciences Antibody Validation" in the resources for more details.

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Immunofluorescence
immunohistochemistry
histology
IHC
Antibody Optimization
Price on request

Full range of antibody optimization levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

Full range of antibody optimization levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

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Immunofluorescence
immunohistochemistry
histology
IHC
Antibody Screening
Price on request

Full range of antibody optimization levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

Full range of antibody optimization levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

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Drug Discovery
Immunofluorescence
immunohistochemistry
histology
Antibody Characterization
Price on request

Full range of antibody characterization levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

Full range of antibody characterization levels for preclinical and clinical histopathological applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

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Immunofluorescence
immunohistochemistry
histology
IHC
Quantitative Histology
Price on request

Full service histology lab offering histological staining, immunohistochemistry, immunofluorescence, in situ hybridization with whole slide imaging and quantitative analysis

Full service histology lab offering histological staining, immunohistochemistry, immunofluorescence, in situ hybridization with whole slide imaging and quantitative analysis

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Human
Bovine
Mouse
Pig
Rat
Xenografts
Cancer
Oncology
Humanized mouse
FFPE tissue
Biology
Drug Discovery
CNS/Neurology
Leica BOND-III
Immunofluorescence
immunohistochemistry
monoclonal antibodies
antibodies
Dolphin
Non-Alcoholic Steatohepatitis (NASH)
FFPE
Machine learning
PD-L1
FFPE
Transgenic mouse
cd8
3DHISTECH Pannoramic 250 Flash III
CD3
CD4
CD31
CD68
FOXP3
PD1
Ki67
pan-cytokeratin
Digital Pathology Software
Price on request

Our proprietary ImageDx software quickly and accurately analyzes images cell-by-cell for positivity and intensity to turn your tissue images into hard quantitative data. Request a quote today for more information.

Our proprietary ImageDx software quickly and accurately analyzes images cell-by-cell for positivity and intensity to turn your tissue images into hard quantitative data. Request a quote today for more information.

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Cancer
Biology
Drug Discovery
Machine learning
Deep Learning
Artificial Intelligence
Quantitative Image Analysis
Price on request

Our proprietary ImageDx software quickly and accurately analyzes images cell-by-cell for positivity and intensity to turn your tissue images into hard quantitative data. Request a quote today for more information.

Our proprietary ImageDx software quickly and accurately analyzes images cell-by-cell for positivity and intensity to turn your tissue images into hard quantitative data. Request a quote today for more information.

« Show less
Oncology
Biology
Drug Discovery
CNS/Neurology
Machine learning
Deep Learning
Artificial Intelligence
Biomarker Analysis
Price on request

Antibody selection and procurement services along with a full range of optimization levels for preclinical and clinical applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background. Immunohistochemistry... Show more »

Antibody selection and procurement services along with a full range of optimization levels for preclinical and clinical applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background. Immunohistochemistry and immunofluorescence available. Single-plex and multi-plex staining. Download "Reveal Biosciences Validated Biomarkers Feb 2018.pdf" in the resources for a list of our validated protocols.

« Show less
Cancer
multiplex
FFPE tissue
Biology
Drug Discovery
Leica BOND-III
Immunofluorescence
immunohistochemistry
Dual-stain Immunohistochemistry
monoclonal antibodies
antibodies
FFPE
Singlex
PD-L1
FFPE
cd8
3DHISTECH Pannoramic 250 Flash III
CD3
CD4
CD31
CD68
FOXP3
PD1
Ki67
pan-cytokeratin
Bright-Field Microscopy
Price on request
  • High resolution whole slide imaging in bright field and fluorescence​
  • Award-winning image quality
  • 20x (0.8 NA) and 40x (0.95 NA) magnification options; z-stacks available
  • Fast turn-around high throughput whole slide scanning
  • Comprehensive image QC process
    Our imaging suite includes whole slide scanning in both... Show more »
  • High resolution whole slide imaging in bright field and fluorescence​
  • Award-winning image quality
  • 20x (0.8 NA) and 40x (0.95 NA) magnification options; z-stacks available
  • Fast turn-around high throughput whole slide scanning
  • Comprehensive image QC process
    Our imaging suite includes whole slide scanning in both bright field and fluorescence using a range of slide scanning and imaging instruments from leading manufacturers including 3DHISTECH. Our comprehensive Quality Management Program includes a deep learning-based image quality application to automatically assess focus and image quality at scale.

Whole slide imaging for small or large-scale studies, including clinical trials.

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Cancer
Biology
Drug Discovery
Leica BOND-III
whole slide imaging
tissue section imaging
3DHISTECH Pannoramic 250 Flash III
3DHISTECH Pannoramic SCAN II
Histology Control Slides
Price on request

High quality control slides for histological staining.

High quality control slides for histological staining.

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Cancer
Biology
Drug Discovery
Leica BOND-III
histology
microscopy
Coverslipping
Price on request

Thin glass covering used to protect and preserve samples on slides. Service included in all histological staining, immunohistochemisty, immunofluorescence and in situ hybridization.

Thin glass covering used to protect and preserve samples on slides. Service included in all histological staining, immunohistochemisty, immunofluorescence and in situ hybridization.

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Cancer
Biology
Drug Discovery
Leica BOND-III
Cryoembedding
Price on request

Cryoprotecting and embedding of tissues for frozen sections with an astute level of control and predictability.

Cryoprotecting and embedding of tissues for frozen sections with an astute level of control and predictability.

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Cancer
Biology
Drug Discovery
Leica BOND-III
cryoprotection
cryoembedding
Cryosectioning
Price on request

OCT embedded frozen tissues are sectioned by our experienced histologists for histological staining or unstained slides

OCT embedded frozen tissues are sectioned by our experienced histologists for histological staining or unstained slides

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Cancer
Biology
Drug Discovery
Leica BOND-III
histology
OCT
cryosectioning
frozen sectioning
Microm HM 505 E Cryostat
cryotomy
Whole Slide Imaging/Digital Slide Scanning
Price on request

We offer bright field or fluorescent digital whole slide scanning using a 3D Histech Pannoramic SCAN scanner. High resolution images are provided with accompanying free software that allows image manipulation including zoom, rotation and channel selection.

We offer bright field or fluorescent digital whole slide scanning using a 3D Histech Pannoramic SCAN scanner. High resolution images are provided with accompanying free software that allows image manipulation including zoom, rotation and channel selection.

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Human
Mouse
Rat
Cancer
Oncology
FFPE tissue
Biology
Drug Discovery
Acute Lymphocytic Leukemia (ALL)
Leica BOND-III
microscopy
Diseased human tissue
Normal Human tissue
Fluorescence
FFPE
whole slide imaging
tissue section imaging
3DHISTECH Pannoramic SCAN II
Fluorescence-Based Microscopy
Price on request

High resolution whole slide imaging in fluorescence​
Award-winning image quality
20x (0.8 NA) and 40x (0.95 NA) fluorescence magnification options
Up to 9-channel fluorescent channel scanning
Z stack up to 30 layers
Multi-layer scanning for perfect co-localization in FISH studies
Fast turn-around high throughput whole slide scanning
Comprehensive image QC process

High resolution whole slide imaging in fluorescence​
Award-winning image quality
20x (0.8 NA) and 40x (0.95 NA) fluorescence magnification options
Up to 9-channel fluorescent channel scanning
Z stack up to 30 layers
Multi-layer scanning for perfect co-localization in FISH studies
Fast turn-around high throughput whole slide scanning
Comprehensive image QC process

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Cancer
Biology
Drug Discovery
Leica BOND-III
Immunofluorescence
FISH
IF
Fluorescence in situ Hybridization
3DHISTECH Pannoramic SCAN II
Formalin Fixation
Price on request

Tissue fixation in 10% Neutral Buffered Formalin (NBF) that ensures excellent preservation of tissue and cellular morphology for histological sections prior to processing and embedding.

Tissue fixation in 10% Neutral Buffered Formalin (NBF) that ensures excellent preservation of tissue and cellular morphology for histological sections prior to processing and embedding.

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Cancer
Oncology
Biology
Drug Discovery
Leica BOND-III
Fresh Tissue
Fresh Tumors
Tissue Decalcification
Price on request

Formic Acid Tissue Decalcification
A weak acid used to decalcify samples for processing. Formic Acid is commonly used as it is a more gentle acid, and less likely to interfere with nuclear staining.

EDTA Tissue Decalcification
Ethylenediaminetetracetic acid (EDTA) decalcifying process; typically used for research... Show more »

Formic Acid Tissue Decalcification
A weak acid used to decalcify samples for processing. Formic Acid is commonly used as it is a more gentle acid, and less likely to interfere with nuclear staining.

EDTA Tissue Decalcification
Ethylenediaminetetracetic acid (EDTA) decalcifying process; typically used for research applications with very high quality morphology or particular molecular elements preservation requirements (IHC, FISH).

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Cancer
Biology
Drug Discovery
Leica BOND-III
H&E Staining
Hematoxylin and eosin staining
Price on request

Hematoxylin and eosin staining on both frozen and FFPE tissue sections.

Hematoxylin and eosin staining on both frozen and FFPE tissue sections.

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Human
Mouse
Rodents
Oncology
FFPE tissue
Biology
Drug Discovery
Leica BOND-III
Non-Alcoholic Steatohepatitis (NASH)
Hematoxylin
Eosin
FFPE
Toxicology
Histology and Pathology Services
Price on request

Slide preparation in either paraffin (FFPE) or Optimal Cutting Temperature (OCT, frozen sections). RNAse-free sections can be prepared on request. Histology services include:
-Tissue trimming
-Paraffin processing and embedding
-Microtomy and RNAse-free microtomy
-Cryotomy
-Decalcification of bone
-Hematoxylin & Eosin... Show more »

Slide preparation in either paraffin (FFPE) or Optimal Cutting Temperature (OCT, frozen sections). RNAse-free sections can be prepared on request. Histology services include:
-Tissue trimming
-Paraffin processing and embedding
-Microtomy and RNAse-free microtomy
-Cryotomy
-Decalcification of bone
-Hematoxylin & Eosin (H&E) stain
-Wide range of special stains
-Pathology review by a Board Certified DVM or MD pathologist

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Human
Mouse
Trichrome stain
Rodents
Cancer
Oncology
FFPE tissue
Biology
Drug Discovery
Leica BOND-III
Immunofluorescence
immunohistochemistry
histology
IHC
Diseased human tissue
Hematoxylin
Eosin
tumor
Machine learning
PD-L1
FFPE
cryoembedding
cryosectioning
tissue section imaging
cd8
CD3
CD4
CD31
CD68
FOXP3
PD1
Ki67
pan-cytokeratin
Digital Pathology Image Analysis
Price on request

Our proprietary ImageDx software quickly and accurately analyzes images cell-by-cell for positivity and intensity to turn your tissue images into hard quantitative data. Custom quantification available to meet your study goals.

Our proprietary ImageDx software quickly and accurately analyzes images cell-by-cell for positivity and intensity to turn your tissue images into hard quantitative data. Custom quantification available to meet your study goals.

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Human
Mouse
Rat
Dog
Machine learning
Deep Learning
Artificial Intelligence
Histopathological Examination
Price on request

Pathology review by a Board Certified pathologist

Pathology review by a Board Certified pathologist

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Immunocytochemistry
Price on request

We offer immunohistochemistry and immunofluorescent staining services in fixed cells. Request a quote today for more information.

We offer immunohistochemistry and immunofluorescent staining services in fixed cells. Request a quote today for more information.

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Cancer
Biology
Drug Discovery
Leica BOND-III
3DHISTECH Pannoramic SCAN II
Immunofluorescence
Price on request

We offer high quality singleplex or multiplex immunofluorescent (IF) staining of your OCT or FFPE samples (tissue or fixed cells). Optimization of your antibody of interest is available on request. Contact us for more information on our IF services.

We offer high quality singleplex or multiplex immunofluorescent (IF) staining of your OCT or FFPE samples (tissue or fixed cells). Optimization of your antibody of interest is available on request. Contact us for more information on our IF services.

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Human
Mouse
Rodents
Cancer
Oncology
multiplex
FFPE tissue
Biology
Drug Discovery
CNS/Neurology
Leica BOND-III
Immunofluorescence
microscopy
monoclonal antibodies
antibodies
Singlex
OCT
PD-L1
FFPE
AlexaFluor
cd8
3DHISTECH Pannoramic 250 Flash III
3DHISTECH Pannoramic SCAN II
CD3
CD4
CD31
CD68
FOXP3
PD1
Ki67
pan-cytokeratin
Alexa Fluor 488
Alexa Fluor 546
Alexa Fluor 647
Immunohistochemistry (IHC)
Price on request

Our IHC service includes staining of paraffin (FFPE) or frozen tissue sections. Assay development and optimization using colorimetric, fluorescent and multiplex approaches are available. Optimization of your choice of antibody and detection system is also available on request.
Our state-of-the-art Leica Bond immunostainer... Show more »

Our IHC service includes staining of paraffin (FFPE) or frozen tissue sections. Assay development and optimization using colorimetric, fluorescent and multiplex approaches are available. Optimization of your choice of antibody and detection system is also available on request.
Our state-of-the-art Leica Bond immunostainer produces consistent quality high throughput immunohistochemistry (IHC). We have developed and validated a wide range of automated IHC protocols for rodent and human tissue. Ask us about our validated protocols.

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Cancer
Oncology
Biology
Drug Discovery
CNS/Neurology
Leica BOND-III
immunohistochemistry
IHC
Cytokines
PD-L1
cd8
3DHISTECH Pannoramic 250 Flash III
CD3
CD4
CD31
CD68
FOXP3
PD1
Ki67
pan-cytokeratin
Immuno-Oncology
In situ Hybridization (ISH)
In Situ Hybridization
Price on request

We offer high quality singleplex and multiplex in situ hybridization (ISH) to localize mRNA in your tissue samples, using the two leading ISH technologies ViewRNA (Thermo Fisher Scientific) and RNascope (ACD). Custom probes can be provided on request, please contact us to discuss your needs.
Tissue preparation including wax... Show more »

We offer high quality singleplex and multiplex in situ hybridization (ISH) to localize mRNA in your tissue samples, using the two leading ISH technologies ViewRNA (Thermo Fisher Scientific) and RNascope (ACD). Custom probes can be provided on request, please contact us to discuss your needs.
Tissue preparation including wax processing, embedding and RNAse-free sectioning (microtomy), or frozen section preparation (cryotomy) are also available on request.
In addition, we offer digital slide scanning and image analysis, resulting in quantitative ISH data.

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Cancer
Oncology
Biology
Drug Discovery
CNS/Neurology
Leica BOND-III
FISH
mRNA
3DHISTECH Pannoramic 250 Flash III
in situ hybridization
ish
Mallory's Trichrome Staining
Price on request

Mallory's triple stain is composed of aniline blue, acid fuchsin, and orange G solution and is commonly used for distinguishing cellular from extracellular components.

Mallory's triple stain is composed of aniline blue, acid fuchsin, and orange G solution and is commonly used for distinguishing cellular from extracellular components.

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Trichrome stain
Biology
Drug Discovery
Leica BOND-III
histology
Masson's Trichrome Staining
Price on request

This three-color staining protocol is used to distinguish cells from surrounding connective tissue; red reveals keratin and muscle fibers, blue- collagen and bone, dark pink- cytoplasm, and brown- cell nuclei. This staining is ideal for tissue fibrosis visualization.

This three-color staining protocol is used to distinguish cells from surrounding connective tissue; red reveals keratin and muscle fibers, blue- collagen and bone, dark pink- cytoplasm, and brown- cell nuclei. This staining is ideal for tissue fibrosis visualization.

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Human
Mouse
Trichrome stain
Rodents
Biology
Drug Discovery
Leica BOND-III
Diseased human tissue
Non-Alcoholic Steatohepatitis (NASH)
liver
Toxicology
human
Microscopy Image Analysis
Price on request

Our proprietary ImageDx software quickly and accurately analyzes images for marker positivity and intensity to turn your tissue images into hard quantitative data. Request a quote today for more information.

Our proprietary ImageDx software quickly and accurately analyzes images for marker positivity and intensity to turn your tissue images into hard quantitative data. Request a quote today for more information.

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Cancer
Oncology
Biology
Drug Discovery
CNS/Neurology
Machine learning
Cell Morphometry
Price on request

Morphometric analysis of a tissue slide; provides values referring to the metric dimensions of cells.

Morphometric analysis of a tissue slide; provides values referring to the metric dimensions of cells.

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Cancer
Biology
Drug Discovery
Leica BOND-III
Paraffin Embedding
Price on request

We offer paraffin-embedding of fixed and processed tissue samples and cells. Contact us for more information.

We offer paraffin-embedding of fixed and processed tissue samples and cells. Contact us for more information.

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FFPE tissue
FFPE
Periodic Acid-Schiff (PAS) Staining
Price on request

A staining method used for demonstration of polysaccharides and mucosubstances in tissues.

A staining method used for demonstration of polysaccharides and mucosubstances in tissues.

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Oncology
FFPE tissue
CNS/Neurology
Leica BOND-III
Frozen Tissue
Periodic Acid Schiff
FFPE
Paraffin Sectioning
Price on request

Human or animal paraffin embedded tissue sectioned using a microtome (microtomy) and prepared for staining and/or analysis.

Human or animal paraffin embedded tissue sectioned using a microtome (microtomy) and prepared for staining and/or analysis.

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Cancer
Oncology
Biology
Drug Discovery
Leica BOND-III
Microm HM 340 E Microtome
Veterinary Pathology
Price on request

Pathology review by a Board Certified DVM pathologist

Pathology review by a Board Certified DVM pathologist

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Mouse
Rat
Dog
Leica BOND-III
histology
Special Slide Staining
Price on request

Various alternative staining techniques to detect, visualize, and evaluate particular tissue structures, elements or substances. We have more than 100 stains, including Masson’s Trichrome, Picrosirius Red, Oil Red O, Periodic Acid Schiff (PAS), Luxol Fast Blue (LFB), Nissl.

Various alternative staining techniques to detect, visualize, and evaluate particular tissue structures, elements or substances. We have more than 100 stains, including Masson’s Trichrome, Picrosirius Red, Oil Red O, Periodic Acid Schiff (PAS), Luxol Fast Blue (LFB), Nissl.

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Human
Mouse
Rodents
Oncology
FFPE tissue
Leica BOND-III
histology
Oil Red O
Periodic Acid Schiff
FFPE
Masson's Trichrome
Niss1
Picrosirius Red
TUNEL
Luxol Fast Blue
Prussian Blue
Fluorojade
TUNEL Assay
Terminal deoxynucleotidyl transferase dUTP nick end labeling assay
Price on request

Automated TUNEL assay available for the detection of apoptotic cells in tissue sections. This assay can be performed on FFPE or frozen tissue sections from a range of species. Tissue preparation including wax processing, embedding and sectioning (microtomy), or frozen section preparation (cryotomy) also available on request. ... Show more »

Automated TUNEL assay available for the detection of apoptotic cells in tissue sections. This assay can be performed on FFPE or frozen tissue sections from a range of species. Tissue preparation including wax processing, embedding and sectioning (microtomy), or frozen section preparation (cryotomy) also available on request. Additionally, digital slide scanning and TUNEL quantification are available if needed.

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Leica BOND-III
Tissue Microarrays
Price on request

A cost-effective approach to immunohistochemistry (IHC) on a range of high quality TMAs from multiple tissue types, delivering IHC data from a large number of patient samples. A cost-effective approach to immunohistochemistry (IHC) on a range of high quality TMAs from multiple tissue types, delivering IHC data from a large number... Show more »

A cost-effective approach to immunohistochemistry (IHC) on a range of high quality TMAs from multiple tissue types, delivering IHC data from a large number of patient samples. A cost-effective approach to immunohistochemistry (IHC) on a range of high quality TMAs from multiple tissue types, delivering IHC data from a large number of patient samples. Cancers of the bladder, breast, colon, endometrium, esophagus, kidney, liver, lung, brain, ovary, testis, pancreas, prostate, rectum, skin, stomach, thyroid and lymphoma available.

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Human
Mouse
Rat
Melanoma
Leica BOND-III
Colorectal cancer
microarrays
Diseased human tissue
Normal Human tissue
Prostate Cancer
Breast cancer
Lung Cancer
Ovarian Cancer
Gastric Cancer
Pancreatic cancer
Liver cancer
Bladder cancer
Lymphoma
Tissue Preparation
Price on request

Tissue trimming, tissue sectioning, tissue fixation, paraffin processing, embedding and staining for immunohistochemical (IHC), immunofluorescence (IF), or in situ hybridization (ISH) analysis.

Tissue trimming, tissue sectioning, tissue fixation, paraffin processing, embedding and staining for immunohistochemical (IHC), immunofluorescence (IF), or in situ hybridization (ISH) analysis.

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FFPE tissue
Leica BOND-III
FFPE
tissue section imaging
Microm HM 505 E Cryostat
Microm HM 340 E Microtome
Toluidine Blue Staining
Price on request

A basic thiazine metachromatic dye that selectively stains acidic tissue components; often used for staining tissues rich in DNA and RNA.

A basic thiazine metachromatic dye that selectively stains acidic tissue components; often used for staining tissues rich in DNA and RNA.

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Leica BOND-III
Two-Photon Excitation Microscopy
Price on request

A fluorescence imaging technique that allows imaging of living tissue up to a very high depth of about one millimeter. The use of infrared light minimizes scattering in the tissue; two-photon excitation can be a superior alternative to confocal microscopy due to its deeper tissue penetration, efficient light detection, and reduced phototoxicity.

A fluorescence imaging technique that allows imaging of living tissue up to a very high depth of about one millimeter. The use of infrared light minimizes scattering in the tissue; two-photon excitation can be a superior alternative to confocal microscopy due to its deeper tissue penetration, efficient light detection, and reduced phototoxicity.

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Leica BOND-III
microscopy
Fluorescence
3DHISTECH Pannoramic SCAN II
Widefield Fluorescence Microscopy
Price on request

Imaging and scanning of histopathological slides using widefield fluorescence microscopy.

Imaging and scanning of histopathological slides using widefield fluorescence microscopy.

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Cancer
FFPE tissue
Biology
Drug Discovery
Leica BOND-III
histology
microscopy
Fluorescence
FFPE
3DHISTECH Pannoramic SCAN II
Computational Modeling
Price on request

Our computational pathology team offers a range of quantitative options from traditional cell-by-cell machine learning-based analysis to artificial intelligence (AI) and deep learning-based applications. Accurate, reproducible, scalable data.

Our computational pathology team offers a range of quantitative options from traditional cell-by-cell machine learning-based analysis to artificial intelligence (AI) and deep learning-based applications. Accurate, reproducible, scalable data.

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Biology
Drug Discovery
Machine learning
Deep Learning
Artificial Intelligence
Biospecimens
Price on request

High quality formalin-fixed paraffin embedded (FFPE) tissue microarrays cut fresh to order. Cancers of the bladder, breast, colon, endometrium, esophagus, kidney, liver, lung, brain, ovary, testis, pancreas, prostate, rectum, skin, stomach, thyroid and lymphoma, multi-tumor and normal tissue TMAs available.

High quality formalin-fixed paraffin embedded (FFPE) tissue microarrays cut fresh to order. Cancers of the bladder, breast, colon, endometrium, esophagus, kidney, liver, lung, brain, ovary, testis, pancreas, prostate, rectum, skin, stomach, thyroid and lymphoma, multi-tumor and normal tissue TMAs available.

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Human
Mouse
Cancer
Melanoma
Biology
Drug Discovery
Colorectal cancer
microarrays
Diseased human tissue
Normal Human tissue
Prostate Cancer
Breast cancer
Respiratory
Nephrology and Urology
Lung Cancer
Ovarian Cancer
Gastric Cancer
FFPE
Pancreatic cancer
Liver cancer
Bladder cancer
Lymphoma
human
Esophageal cancer
Hepatology
Tissue Fixation
Price on request

Our experienced scientists will ensure your tissue is fully fixed prior to processing.

Our experienced scientists will ensure your tissue is fully fixed prior to processing.

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Oncology
Fresh Tissue
Fresh Tumors
Biomarkers
Price on request

Hundreds of biomarkers optimized for single and multi-plex immunohistochemistry and immunofluorescence or we can optimize your marker of interest. Download "Reveal Biosciences Validated Biomarkers Feb 2018.pdf" in the resources for a list of our validated protocols.

Hundreds of biomarkers optimized for single and multi-plex immunohistochemistry and immunofluorescence or we can optimize your marker of interest. Download "Reveal Biosciences Validated Biomarkers Feb 2018.pdf" in the resources for a list of our validated protocols.

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Cancer
Biology
Drug Discovery
Immunofluorescence
immunohistochemistry
IHC
PD-L1
cd8
CD3
CD4
CD31
CD68
FOXP3
PD1
Ki67
pan-cytokeratin
Clinical Research
Price on request

Our full service histology laboratory offers fast turnaround, high quality reproducible results and a multi-step QC process.

Our full service histology laboratory offers fast turnaround, high quality reproducible results and a multi-step QC process.

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Cancer
Biology
Drug Discovery
Clinical Laboratory Services
Price on request

Our full service histology laboratory offers fast turnaround, high quality reproducible results and a multi-step QC process.

Our full service histology laboratory offers fast turnaround, high quality reproducible results and a multi-step QC process.

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Cancer
Biology
Drug Discovery
Tissue Embedding
Price on request

Our experienced scientists will orient and embed your tissue in paraffin or OCT compound (optimal cutting temperature compound) according to your specifications

Our experienced scientists will orient and embed your tissue in paraffin or OCT compound (optimal cutting temperature compound) according to your specifications

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Human
Mouse
Rodents
Oncology
FFPE tissue
CNS/Neurology
OCT
FFPE
Antibody Services
Price on request

Antibody selection and procurement services along with a full range of optimization levels for preclinical and clinical applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

Antibody selection and procurement services along with a full range of optimization levels for preclinical and clinical applications. Primary antibodies are tested on positive control tissue to determine optimal concentration and antigen retrieval conditions with a strong positive signal and low background.

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Human
Rabbit
Mouse
Rat
Cancer
Biology
Drug Discovery
Leica BOND-III
Common Histochemical Stains
Price on request

Our histology lab offers H&E staining, Masson's Trichrome, PAS, Oil Red O, Nissl, Picrosirius red, TUNEL, Luxol Fast blue, Prussian blue, and Fluorojade. Ask us about other special stains.

Our histology lab offers H&E staining, Masson's Trichrome, PAS, Oil Red O, Nissl, Picrosirius red, TUNEL, Luxol Fast blue, Prussian blue, and Fluorojade. Ask us about other special stains.

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Human
Rabbit
Mouse
Rat
Trichrome stain
Iron hemotoxylin stain
Dog
Cancer
Biology
Drug Discovery
Dolphin
Hematoxylin
Eosin
Oil Red O
Masson's Trichrome
PAS
Niss1
Picrosirius Red
TUNEL
Luxol Fast Blue
Prussian Blue
Flurojade
Clinical and Anatomic Pathology
Price on request

Pathological evaluation by board certified pathologist

Pathological evaluation by board certified pathologist

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Cancer
Biology
Drug Discovery
Immunostaining
Price on request

We offer immunostaining of your OCT and FFPE samples. Assay development and optimization using colorimetric, fluorescent and multiplex approaches are available.
Our state-of-the-art Leica Bond immunostainer produces consistent quality high throughput immunohistochemistry (IHC). We have developed and validated a wide range of... Show more »

We offer immunostaining of your OCT and FFPE samples. Assay development and optimization using colorimetric, fluorescent and multiplex approaches are available.
Our state-of-the-art Leica Bond immunostainer produces consistent quality high throughput immunohistochemistry (IHC). We have developed and validated a wide range of automated IHC protocols for rodent and human tissue. Ask us about our validated protocols.

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Cancer
Biology
Drug Discovery
immunohistochemistry
IHC
Protein Expression Visualization
Price on request

Visualization and quantitation of protein biomarkers in human or animal tissue using immunohistochemistry (IHC) or immunofluorescence (IF). Hundreds of protein biomarkers protocols available. Download "Reveal Biosciences Validated Biomarkers Feb 2018.pdf" in the resources for a list of our validated protocols.

Visualization and quantitation of protein biomarkers in human or animal tissue using immunohistochemistry (IHC) or immunofluorescence (IF). Hundreds of protein biomarkers protocols available. Download "Reveal Biosciences Validated Biomarkers Feb 2018.pdf" in the resources for a list of our validated protocols.

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Cancer
Oncology
Biology
Drug Discovery
Leica BOND-III
immunohistochemistry
IHC
cd8
Image Analysis
Price on request

Our proprietary ImageDx software quickly and accurately analyzes images cell-by-cell for marker positivity and intensity to turn your tissue images into hard quantitative data. Request a quote today for more information.

Our proprietary ImageDx software quickly and accurately analyzes images cell-by-cell for marker positivity and intensity to turn your tissue images into hard quantitative data. Request a quote today for more information.

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Cancer
Biology
Drug Discovery
Machine learning
Deep Learning
Artificial Intelligence
Data Services
Price on request

Our computational pathology team offers a range of quantitative options from traditional cell-by-cell machine learning-based analysis to artificial intelligence (AI) and deep learning-based applications. Accurate, reproducible, scalable data.

Our computational pathology team offers a range of quantitative options from traditional cell-by-cell machine learning-based analysis to artificial intelligence (AI) and deep learning-based applications. Accurate, reproducible, scalable data.

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Cancer
Biology
Drug Discovery
Machine learning
Deep Learning
Artificial Intelligence
Microscopy
Price on request

We offer bright field or fluorescent digital whole slide scanning using a 3D Histech Pannoramic SCAN scanner. High resolution images are provided with accompanying free software that allows image manipulation including zoom, rotation and channel selection.

We offer bright field or fluorescent digital whole slide scanning using a 3D Histech Pannoramic SCAN scanner. High resolution images are provided with accompanying free software that allows image manipulation including zoom, rotation and channel selection.

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Biology
Drug Discovery
microscopy
whole slide imaging
Histological Staining
Price on request

Our full service histology lab offers histochemical stains, immuhistochemistry and immunofluorescent staining.

Our full service histology lab offers histochemical stains, immuhistochemistry and immunofluorescent staining.

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Cancer
Oncology
Biology
Drug Discovery
Immunofluorescence
immunohistochemistry
IHC
Hematoxylin
Eosin
FFPE
FFPE
Cell-Based Assays
Price on request

Processing and embedding of cell pellets. Histological staining, immunohistochemistry, immunofluorescence, in situ hybridization along with whole slide imaging and quantitative image analysis.

Processing and embedding of cell pellets. Histological staining, immunohistochemistry, immunofluorescence, in situ hybridization along with whole slide imaging and quantitative image analysis.

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Cancer
Biology
Drug Discovery
3DHISTECH Pannoramic 250 Flash III
Tissue Processing
Price on request

Fixed or frozen tissue processed for FFPE or OCT blocks. Experienced scientists ensure tissue is properly fixed prior to processing and embedding.

Fixed or frozen tissue processed for FFPE or OCT blocks. Experienced scientists ensure tissue is properly fixed prior to processing and embedding.

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Microm HM 505 E Cryostat
Microm HM 340 E Microtome
Cells and Tissues
Price on request

Procurement of cells and tissue samples to accompany your IHC, IF or ISH study. Reveal offers high quality formalin-fixed paraffin embedded (FFPE) tissue microarrays cut fresh to order.

Procurement of cells and tissue samples to accompany your IHC, IF or ISH study. Reveal offers high quality formalin-fixed paraffin embedded (FFPE) tissue microarrays cut fresh to order.

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Cancer
Melanoma
Biology
Drug Discovery
Colorectal cancer
microarrays
Diseased human tissue
Normal Human tissue
Prostate Cancer
Breast cancer
Lung Cancer
Ovarian Cancer
Gastric Cancer
Pancreatic cancer
Liver cancer
Bladder cancer
Lymphoma
Bioanalysis
Price on request

Quantitative histology services including H&E, special stains, immunohistochemistry, immunofluorescence, and in situ hybridization with whole slide imaging and quantitative analysis

Quantitative histology services including H&E, special stains, immunohistochemistry, immunofluorescence, and in situ hybridization with whole slide imaging and quantitative analysis

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Cancer
Biology
Drug Discovery
Leica BOND-III
3DHISTECH Pannoramic 250 Flash III
Tissue Sectioning
Price on request

High quality sectioning of FFPE or frozen tissue by experienced histologists. Includes slide mounting.

High quality sectioning of FFPE or frozen tissue by experienced histologists. Includes slide mounting.

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FFPE tissue
PDX
FFPE
cryosectioning
frozen sectioning
Microm HM 505 E Cryostat
Microm HM 340 E Microtome
Transmitted Light Microscopy
Price on request
Request a quote for more information about this service.
Drug Discovery & Development
Price on request

Drug Discovery & Development Services

Drug Discovery & Development Services

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Computational Pathology
Price on request

Our computational pathology team offers a range of quantitative options from traditional cell-by-cell machine learning-based analysis to AI and deep learning-based applications. Accurate, reproducible, scalable data.

Our computational pathology team offers a range of quantitative options from traditional cell-by-cell machine learning-based analysis to AI and deep learning-based applications. Accurate, reproducible, scalable data.

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Biology
Drug Discovery
Machine learning
Deep Learning
Artificial Intelligence
Fluorescence in situ Hybridization (FISH)
Price on request

We offer high quality singleplex and multiplex fluorescence in situ hybridization (FISH) to localize mRNA in your tissue samples, using the two leading technologies ViewRNA (Thermo Fisher Scientific) and RNascope (ACD). Custom probes can be provided on request, please contact us to discuss your needs.
Tissue preparation... Show more »

We offer high quality singleplex and multiplex fluorescence in situ hybridization (FISH) to localize mRNA in your tissue samples, using the two leading technologies ViewRNA (Thermo Fisher Scientific) and RNascope (ACD). Custom probes can be provided on request, please contact us to discuss your needs.
Tissue preparation including wax processing, embedding and RNAse-free sectioning (microtomy), or frozen section preparation (cryotomy) are also available on request.
In addition, we offer digital slide scanning and image analysis, resulting in quantitative FISH data.

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FISH
mRNA
Fluorescence
Fluorescence in situ Hybridization
RNA Services
Price on request

We offer high quality singleplex and multiplex fluorescence in situ hybridization (FISH) to localize mRNA in your tissue samples, using the two leading technologies ViewRNA (Thermo Fisher Scientific) and RNascope (ACD). Custom probes can be provided on request, please contact us to discuss your needs.
Tissue preparation... Show more »

We offer high quality singleplex and multiplex fluorescence in situ hybridization (FISH) to localize mRNA in your tissue samples, using the two leading technologies ViewRNA (Thermo Fisher Scientific) and RNascope (ACD). Custom probes can be provided on request, please contact us to discuss your needs.
Tissue preparation including wax processing, embedding and RNAse-free sectioning (microtomy), or frozen section preparation (cryotomy) are also available on request.
In addition, we offer digital slide scanning and image analysis, resulting in quantitative FISH data.

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Pharmacology
Price on request

Pharmacology Services

Pharmacology Services

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Tumor Marker Testing
Price on request

Tumor Marker Testing Services

Tumor Marker Testing Services

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Antibody/Antigen Detection Based Testing
Price on request

Antibody/Antigen Detection Based Testing Services

Antibody/Antigen Detection Based Testing Services

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Clinical Chemistry
Price on request

Clinical Chemistry Services

Clinical Chemistry Services

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2018-09-13 06:06:22 +1200

Net Promoter Score of 8 received for Immunohistochemistry (IHC).

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 5.
2018-04-11 11:49:16 +1200

Net Promoter Score of 10 received for Immunohistochemistry (IHC).

Additional Ratings: satisfaction with deliverable: 9,
March 24, 2018

Positive review received for In situ Hybridization (ISH):

"I worked with Reveal Biosciences twice and I will work with them again and again. Their services exceeded my expectations. My service requests are always followed by many questions, they always answered them promptly ( within 1-2 hrs), clearly and with professionalism. The service turn-out time is really fast and service cost is reasonable. Thank you Reveal Biosciences for facilitating my research ! Mariam Ba"

2018-03-22 10:07:18 +1300

Net Promoter Score of 10 received for In situ Hybridization (ISH).

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-02-07 06:53:19 +1300

Net Promoter Score of 9 received for Tissue Microarrays.

Additional Ratings: satisfaction with deliverable: 9, satisfaction with timeliness: 7.
2018-01-11 11:18:45 +1300

Net Promoter Score of 7 received for In situ Hybridization (ISH).

Additional Ratings: satisfaction with deliverable: 7, satisfaction with timeliness: 7.
2017-10-31 00:17:08 +1300

Net Promoter Score of 10 received for Immunohistochemistry (IHC).

Additional Ratings: satisfaction with timeliness: 5.
2017-10-17 13:08:05 +1300

Net Promoter Score of 8 received for Immunofluorescence.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 4.
2017-08-29 06:44:26 +1200

Net Promoter Score of 5 received for Formalin Fixation.

Additional Ratings: satisfaction with deliverable: 5, satisfaction with timeliness: 4.
2017-05-16 10:53:15 +1200

Net Promoter Score of 10 received for Immunohistochemistry (IHC).

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 10.
March 2, 2017

Positive review received for Immunohistochemistry (IHC):

"Reveal Biosciences performed a very thorough antibody validation for IHC. Even though, we did not find an optimal antibody for our purpose (in spite of an existing antibody validation paper out there), Reveal and Caroline worked very hard to test additional antibodies and were very flexible as the scope of work changed along the way. They were accommodating and professional all the way to completion of the project. We will definitely return back to do additional work with Reveal."

August 1, 2013

Positive review received for Immunofluorescence:

"We have worked with Claire on several occasions and have always been really impressed by her high quality work and excellent service."

July 11, 2013

Positive review received for Immunohistochemistry (IHC):

"Excellent - would highly recommend."

April 26, 2013

Positive review received for Immunohistochemistry (IHC):

"Excellent. Provided very high quality immunohistochemistry images. Communication and service level were excellent."

September 5, 2012

Positive review received for Immunohistochemistry (IHC):

"Excellent service and quick communications, just a pleasure to work with!"

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