Research Blood Components provides human blood and blood products to the biotechnology and pharmaceutical industries, and to academic biomedical researchers throughout the United States. We do not collect blood for clinical use. Our only purpose is to meet the unique needs of the research community. We can provide custom ordered blood products for use in your research. Arrangement can be made for customized collections based on your requirements for donor populations, anticoagulants and collection amounts.
Research Blood Components follows American Association of Blood Banks guidelines for drawing donors. Our regular population consists of healthy males and females between the ages of 18 and 65. All donors complete a uniform blood donor history questionnaire. An IRB approved consent form is obtained from each donor giving us permission to collect their blood and use or sell it at our discretion, for research purposes.
Confidentiality and donor identification is assured, and you will receive only a Research Blood Components assigned tracking number for each individual blood collection service.
Research Blood Components tests each donor's blood for standard blood-borne pathogens prior to the initial donation, and at the time of each subsequent donation. Testing is performed by a laboratory licensed to screen blood donors for ABO/Rh, antibody screen, syphilis serology, anti-HIV I/II, anti-HTLV I/II, hepatitis B surface antigen, HCV antibody, and hepatitis B core antibody. Donors can be tested more frequently, if desired, for an additional charge. Despite negative results, all blood products should be considered potentially infectious and handled in a manner consistent with guidelines to prevent transmission of blood-borne pathogens.
Erythrocytes (red blood cells) are prepared by collecting a unit of whole blood in the anticoagulant of your choice followed by centrifugation to remove most of the plasma, platelets and white blood cells. The resulting red blood cells average 225 milliliters per unit.
Fresh whole blood contains erythrocytes (red blood cells), leukocytes (white blood cells), thrombocytes (platelets) and plasma. Units of whole blood (approximately 450 milliliters) can be collected in CPDA-1, CPD, ACD and sodium heparin anticoagulants. Smaller amounts of whole blood can be collected in a variety of anticoagulants using 10 milliliter Vacutainer tubes.
Platelet concentrates are prepared from units of whole blood. The blood is drawn, maintained and processed at room temperature. The final platelet concentrate contains approximately 25 - 50 billion platelets in 40 - 60 milliliters of plasma.
Buffy coats are prepared by centrifugation of a unit of whole blood. The interface between the plasma and the red blood cells is harvested. The unpurified buffy coat yields approximately 0.5 - 1 billion peripheral blood mononuclear cells and a similar number of neutrophils (polymorphonuclear leukocytes). The buffy coat, as collected, is contaminated with platelets, plasma and red blood cells. Mononuclear cells can be separated by further processing the buffy coat with density gradient centrifugation using ficoll-hypaque.
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