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RD-Biotech SAS

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Besançon, FR

About RD-Biotech SAS

Expert in Antibodies, recombinant Proteins, DNA plasmid and cell engineering since 2002, RD-Biotech is a French Contract Research & Manufacturing Company that offers custom solutions in Bio manufacturing, development and bioanalytical services, as part of Research and Development programs or Pre-clinical studies.


Complying with ISO 9001:2015 Quality Standards, RD-Biotech is the privileged partner of industrial laboratories such as pharmaceutical, in vitro diagnostic, and academic laboratories for their projects in fundamental research or generation of therapeutic tools.


Our competences:
-    Manufacturing in R&D, Preclinical and High Quality Grades of DNA plasmids and monoclonal antibodies.
-    Recombinant protein expression in cell free, CHO, HEK and E.Coli systems, including vector design and construction.
-    Monoclonal antibody generation: Hybridoma and Phage display platforms
-    Platform of antibody engineering: sequencing, chimerization, humanization and reformatting (scFv, Fab, bispecific…)
-    Analytical services: for lead screening, for antibody validation and characterization: ELISA, FACS, Octet, PCR ...and bioassay platform.
-    A range of ELISA kits: FastELISA kits for IgG quantification (mouse, human, rat), Ig isotyping and contaminant detection (protein A, bovine IgG): the most convenient method to quantify IgG with results in only 30 minutes!
-    A range of murine anti-rabies monoclonal antibodies for the quantification of rabies virus by ELISA: Monoclonal antibody 1112-1 (Capture antibody) and Monoclonal antibody D1-25 (Detection antibody, biotinylated). Catalog and bulk format.

Based on a high level of expertise and skills, RD-Biotech implements the most relevant strategies for each project according to the client’s specifications.
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Our Services (39)


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Antibody Cloning

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Protein Expression Screening and Optimization

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Site-Directed Mutagenesis

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Bacterial Protein Expression

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Protein Expression in Mammalian Cells

Mammalian cell based recombinant protein production
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Recombinant DNA Technology

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Recombinant Antigen Development

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Recombinant Antibody Production

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Antibody Engineering

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Antibody Purification

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Antibody Development

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Antibody/Antigen Detection Based Testing

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Antibody Production

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Plasmid DNA Preparation

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In vitro Monoclonal Antibody (mAb) Production

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For several years, RD-Biotech has developed a strong expertise in the in vitro production of monoclonal antibodies. Production in ascites, although still allowed in France, is recognised as painful for the animals and we have replaced it with an entirely in vitro cell culture method.
RD-Biotech offers this alternative technology at an equivalent cost to the old ascitic method but with higher reproducibility and quality.

customers can send their clones to RD-Biotech (by flask or cryovials) for production. You do not have to specify the nature of the clone, which guarantees confidentiality.


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Recombinant Protein Expression

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Hybridoma Development

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Immunoassay Development

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Cell Line Generation

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Plasmid Construction

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Mammalian Cell Culture

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Antibody Services

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Biology

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Plasmids and Vectors

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Cells and Tissues

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Immunoassays

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Bioanalysis

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Nucleic Acid Services

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Polyclonal Antibody Production

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DNA Library Screening

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Protein Production

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Pharmacology & Toxicology

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Biochemistry & Molecular Biology

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Protein Services

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Monoclonal Antibody (mAb) Production

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DNA Extraction and Purification

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Antibody Modification

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In vitro Immunogenicity Assays

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DNA Services

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