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RASA Life Science Informatics

Pune, IN

We are CRISIL rated organization located in Pune which deals in providing the high quality R&D, services and training in the area of life science informatics like bioinformatics, Cheminformatics and BIO-IT. We offer computational and IT solutions to biotechnology, pharmaceutical, chemical and life science institutes and industries. RASA also provides the corporate training to the companies like Wipro and conducts the National level practical oriented workshops in Cheminformatics and bioinformatics comprising the various participants ranging from students, scientists to industrial persons

RASA is a scientific data analytics and Knowledge bases discovery service company with deep focus on Chemical and Life sciences. At RASA we are poised to create revolution in chemical and life sciences domain by giving biologist and chemist from research and industries to enhance their work by using our services and products in... Show more »

We are CRISIL rated organization located in Pune which deals in providing the high quality R&D, services and training in the area of life science informatics like bioinformatics, Cheminformatics and BIO-IT. We offer computational and IT solutions to biotechnology, pharmaceutical, chemical and life science institutes and industries. RASA also provides the corporate training to the companies like Wipro and conducts the National level practical oriented workshops in Cheminformatics and bioinformatics comprising the various participants ranging from students, scientists to industrial persons

RASA is a scientific data analytics and Knowledge bases discovery service company with deep focus on Chemical and Life sciences. At RASA we are poised to create revolution in chemical and life sciences domain by giving biologist and chemist from research and industries to enhance their work by using our services and products in the area of Bioinformatics and Cheminformatics.

As expert technologist we offer faster, better and cost effective cutting edge technology solutions to chemical and life science research and industry.

With our combined experience in Bioinformatics, Cheminformatics and IT with strong advisory board, RASA is set to provide premium services in technology solutions, customized product development and training in the area of life science. We provide our customers with a seamless model of wide expertise and comprehensive platforms.

We are the first Life Sciences technology company from India to provide corporate training to Wipro Limited in area of cheminoformatics.

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DNA Sequencing Data Analysis
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Computational Drug Discovery
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RASA provides a wide array of methods for conventional drug discovery to match the complex and urgent needs of industry. RASA offers high quality non-turnkey approach which emphasizes the importance of expert knowledge of the target field and structural domain. RASA offers services in designing and optimizing virtual library,... Show more »

RASA provides a wide array of methods for conventional drug discovery to match the complex and urgent needs of industry. RASA offers high quality non-turnkey approach which emphasizes the importance of expert knowledge of the target field and structural domain. RASA offers services in designing and optimizing virtual library, scaffold hopping, predicting bioactivity, toxicity and ADME properties, protein-protein, protein-ligand and ligand-ligand interactions.

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Software Development
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To manage the enormous data generated in the life science labs is an uphill task for majority of life science and clinical research institutes and companies. In order to manage this data there has been development of several tools and databases. These tools are very difficult to understand, customize and develop as per the... Show more »

To manage the enormous data generated in the life science labs is an uphill task for majority of life science and clinical research institutes and companies. In order to manage this data there has been development of several tools and databases. These tools are very difficult to understand, customize and develop as per the requirement.

Our Team comprises of experts in the areas of Chemoinformatics, Bioinformatics, Computational Chemistry, Database and Software developments. RASA specializes in designing customized databases according to the customer needs along with the web interface designing. RASA can provide integration of client database to the public available databases. RASA facilitates in solving clients problem by designing customized software solutions in area of life science. List of our Bio-IT services:

  • Database development
  • Customized algorithms and tools development
  • Add-on and customized applications
  • Identification Services
  • Utilities development
  • Web based solutions
  • Desktop solutions
  • Workflow development and integration (KNIME)
  • Technical Support (providing technical support for scientific support as vender.)

Full range of software custom programming:

  • We are experts in programming languages like PHP, MySQL, Perl, Java, R and Python for robust and budget controlled client-server solutions (for any platforms).
  • To deliver results quickly – we consult with you within a given timeframe, gathering information, capturing requirements and providing solutions
  • We focus on the quality of our analysis and reporting as well as on the speed with which we deliver our results. We are very adaptive to our customer needs.
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SNP Genotyping Data Analysis
Single nucelotide polymorphism genotyping data analysis
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NGS Data Analysis
Next generation sequencing data analysis
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This technology revolves around genomics data and is well-known as massively parallel sequencing. NGS technology has lead to exponential increase in the Genomic data which need further processing and analysis.NGS data analysis includes genome assembly, alignment and variation detection .NGS has a broad range of genetic analysis... Show more »

This technology revolves around genomics data and is well-known as massively parallel sequencing. NGS technology has lead to exponential increase in the Genomic data which need further processing and analysis.NGS data analysis includes genome assembly, alignment and variation detection .NGS has a broad range of genetic analysis applications including comparative genomics, high-throughput polymorphism detection, analysis of coding and non-coding RNAs and identifying mutant genes in disease pathways.

We at RASA provide NGS data analysis and NGS product development services. List of our NGS data analysis services:

  • Genome annotation, Gene Prediction
  • Differential Expression Analyses -RNAseq
  • Structural Genomic Variations – SNPs, indels, CNVs detection
  • ChIP – Seq analyses and other Protein – DNA/RNA interactions
  • Metagenomics data analysis
  • Novel Isoform (Alternative Splicing) Identification
  • Small & miRNA Sequencing Analysis
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In silico ADME Modeling
In silico absorption, distribution, metabolism, and excretion
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The "ADME" acronym is commonly used in the pharmaceutical industry to indicate all the phenomena associated with Absorption, Distribution, Metabolism, Elimination. ADME information is critical in all phases of a fully integrated drug development program. A full consideration of all facets of the molecular structure and... Show more »

The "ADME" acronym is commonly used in the pharmaceutical industry to indicate all the phenomena associated with Absorption, Distribution, Metabolism, Elimination. ADME information is critical in all phases of a fully integrated drug development program. A full consideration of all facets of the molecular structure and the impact of that structure on the ADME profile will enable chemists to design out negative ADME attributes (e.g. chemically reactive moieties, avidly metabolized sites) and incorporate "ADME-friendly" attributes (e.g. optimal log P, good membrane permeability).

Hence the prediction of ADME is very critical and helpful in the drug development process. ADME prediction provides the scientist with the following benefits:

  1. Focus research efforts on molecules that meet property requirements
  2. Investigate the influence of changing inter-related properties to gain a deeper understanding of your compounds
  3. Reduce the need for expensive, labor-intensive assays

RASA ADME prediction algorithm calculates :

  1. Intrinsic aqueous solubility of organic compounds predicted in logS (Aqueous Solubility), moles/L and grams/L units at 25 degree Celsius and pH 7
  2. logP (Partition Coefficient) of organic compounds predicted at 25 degree Celsius and pH 7
  3. logD (Distribution Coefficient)of organic compounds predicted at 25 degree Celsius and pH 7
  4. pKa - Ionization Constant of organic compounds predicted at 25 degree Celsius and pH 7

Deliverables

A report highlighting important finding of ADME predictive study, detailed result in Excel format. Output will also be provided in an SDF format comprising structure of input molecules and predictive results.

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Protein Modeling
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Equipment
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Computer Science, Software Development, and IT Services
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Biology
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Biochemistry & Molecular Biology
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Nucleic Acid Services
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Nucleic Acid Analysis
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Nucleic Acid Data Analysis
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Sequencing Data Analysis
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Pharmacology & Toxicology
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ADME/DMPK Studies
Drug Metabolism and Pharmacokinetics
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Drug Discovery & Development
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Drug Discovery
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Computational Modeling
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