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Rapid Novor Inc

25 Orders Completed
Waterloo, Ontario, CA

About Rapid Novor Inc

Rapid Novor Inc. is the world's leader in antibody protein sequencing. Specializing in the field of mass spectrometry-based proteomics, the team has developed the technology to directly sequence antibody proteins without needing to access the cell line. As a University of Waterloo spin-off, the company... Show more »

Rapid Novor Inc. is the world's leader in antibody protein sequencing. Specializing in the field of mass spectrometry-based proteomics, the team has developed the technology to directly sequence antibody proteins without needing to access the cell line. As a University of Waterloo spin-off, the company is building its technologies based on the twenty years of scientific research from Dr. Bin Ma, co-founder and chief scientist. The company's REmAb™ service has allowed for the accurate sequencing of any given antibody proteins on a routine basis. The company's WILD™ service is the first commercially available service that can accurately distinguish Isoleucine and Leucine using mass spectrometry.

Pricing REmAb™ with WILD™ REmAb™ Expedite
Price per mAb US$12,999 (US$4,999 ***) Add US$2,000
Ile/Leu calls Determined by w-ion
Turnaround 2 weeks 1 week
Report HC and LC full sequences HC and LC full sequences

*** For a LIMITED TIME only, introductory discount to new customers in the first order.

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Our Services (10)


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De Novo Antibody Sequencing

Starting at $4,999.00 per sample
Pricing REmAb™ with WILD™ REmAb™ Expedite
Price per mAb US$12,999 (US$4,999 ***) Add US$2,000
Ile/Leu calls Determined by w-ion
Turnaround 2 weeks 1 week
Report HC and LC full sequences HC and LC full sequences

*** For a LIMITED TIME... Show more »

Pricing REmAb™ with WILD™ REmAb™ Expedite
Price per mAb US$12,999 (US$4,999 ***) Add US$2,000
Ile/Leu calls Determined by w-ion
Turnaround 2 weeks 1 week
Report HC and LC full sequences HC and LC full sequences

*** For a LIMITED TIME only, introductory discount to new customers in the first order.

You provide: Monoclonal antibody sample (>0.2mg, >95% purity, >0.5mg/mL concentration, without excessive BSA or other proteins)
We deliver: Full sequence of heavy and light chains; Full sequence coverage by LC-MS/MS; Comprehensive report.

Money-back guarantee – We guarantee at least 5X coverage of the CDRs, 3X coverage for 95% of the sequence, and 1X coverage for the full length. If the target coverage is not met, you will be fully refunded.

Service Overview

Rapid Novor offers antibody de novo sequencing service. We directly sequence the antibody protein using multiple enzyme digestion and high resolution LC-MS/MS. Our service guarantees full length sequencing of the heavy and light chains.

Our sequencing process does not require hybridoma, mRNA, or other sequence information. It provides a direct and independent insight into your antibody sample.

Accurate – We guarantee at least 5X coverage of CDRs in the variable regions. Every amino acid in the CDRs is confidently supported by fragment ions in at least five MS2 scans. For isomeric Leu and Ile, we strive to make correct inference from enzyme specificity and statistics in antibody database.

Comprehensive – As an option, we offer comprehensive characterization of the antibody protein. Our service includes the analyses of PTMs, glycosylation, disulphide bridges, contaminants, and other aspects customized to your needs.

Efficient – We use minimal amount of antibody sample (0.1 mg) and deliver results within 2 weeks with consistent quality.

Method

Our team specializes in protein mass spectrometry and informatics. We develop proprietary workflow and software for antibody de novo sequencing. Our standard procedure consists of the following steps.

  1. Digest the antibody protein into overlapping peptides with multiple enzymes.
  2. Analyze the digestions with LC-MS/MS using a Thermo Orbitrap mass spectrometer.
  3. Characterize overlapping peptides with de novo peptide sequencing.
  4. Automated antibody sequence assembly from characterized peptides.
  5. Result examination and annotation by our scientists.
Show less
Q Exactive Orbitrap LC-MS/MS system Human Hamster Rabbit Sheep Goat Mouse Rat Camelids novor Mass Spectrometry de novo de novo sequencing REmAb™ WILD™ protein sequencing Antibodies Monoclonal antibodies Show 18 more tags Show less

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Antibody Protein Sequencing

Starting at $4,999.00 per sample
Pricing REmAb™ with WILD™ REmAb™ Expedite
Price per mAb US$12,999 (US$4,999 ***) Add US$2,000
Ile/Leu calls Determined by w-ion
Turnaround 2 weeks 1 week
Report Heavy and light chain full sequences Heavy and light chain full sequences... Show more »
Pricing REmAb™ with WILD™ REmAb™ Expedite
Price per mAb US$12,999 (US$4,999 ***) Add US$2,000
Ile/Leu calls Determined by w-ion
Turnaround 2 weeks 1 week
Report Heavy and light chain full sequences Heavy and light chain full sequences

*** For a LIMITED TIME only, introductory discount to new customers in the first order.

You provide: Monoclonal antibody sample (>0.2mg, >95% purity, >0.5mg/mL concentration, without excessive BSA or other proteins)
We deliver: Full sequence of heavy and light chains; Full sequence coverage by LC-MS/MS; Comprehensive report.

Money-back guarantee – We guarantee at least 5X coverage of the CDRs, 3X coverage for 95% of the sequence, and 1X coverage for the full length. If the target coverage is not met, you will be fully refunded.

Service Overview

Rapid Novor offers antibody de novo sequencing service. We directly sequence the antibody protein using multiple enzyme digestion and high resolution LC-MS/MS. Our service guarantees full length sequencing of the heavy and light chains.

Our sequencing process does not require hybridoma, mRNA, or other sequence information. It provides a direct and independent insight into your antibody sample.

Accurate – We guarantee at least 5X coverage of CDRs in the variable regions. Every amino acid in the CDRs is confidently supported by fragment ions in at least five MS2 scans. For isomeric Leu and Ile, we strive to make correct inference from enzyme specificity and statistics in antibody database.

Comprehensive – As an option, we offer comprehensive characterization of the antibody protein. Our service includes the analyses of PTMs, glycosylation, disulphide bridges, contaminants, and other aspects customized to your needs.

Efficient – We use minimal amount of antibody sample (0.2 mg) and deliver results within 15 business days with consistent quality.

Method

Our team specializes in protein mass spectrometry and informatics. We develop proprietary workflow and software for antibody de novo sequencing. Our standard procedure consists of the following steps.

  1. Digest the antibody protein into overlapping peptides with multiple enzymes.
  2. Analyze the digestions with LC-MS/MS using a Thermo Orbitrap mass spectrometer.
  3. Characterize overlapping peptides with de novo peptide sequencing.
  4. Automated antibody sequence assembly from characterized peptides.
  5. Result examination and annotation by our scientists.
Show less
Thermo Fisher Q-Exactive Thermo Fisher Lumos novor LC-MS/MS de novo sequencing

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Antibody Sequencing

Starting at $4,999.00 per sample
Pricing REmAb™ with WILD™ REmAb™ Expedite
Price per mAb US$12,999 (US$4,999 ***) Add US$2,000
Ile/Leu calls Determined by w-ion
Turnaround 2 weeks 1 week
Report Heavy and light chain full sequences Heavy and light chain full sequences... Show more »
Pricing REmAb™ with WILD™ REmAb™ Expedite
Price per mAb US$12,999 (US$4,999 ***) Add US$2,000
Ile/Leu calls Determined by w-ion
Turnaround 2 weeks 1 week
Report Heavy and light chain full sequences Heavy and light chain full sequences

*** For a LIMITED TIME only, introductory discount to new customers in the first order.

You provide: Monoclonal antibody sample (>0.2mg, >95% purity, >0.5mg/mL concentration, without excessive BSA or other proteins)
We deliver: Full sequence of heavy and light chains; Full sequence coverage by LC-MS/MS; Comprehensive report.

Money-back guarantee – We guarantee at least 5X coverage of the CDRs, 3X coverage for 95% of the sequence, and 1X coverage for the full length. If the target coverage is not met, you will be fully refunded.

Service Overview

Rapid Novor offers antibody de novo sequencing service. We directly sequence the antibody protein using multiple enzyme digestion and high resolution LC-MS/MS. Our service guarantees full length sequencing of the heavy and light chains.

Our sequencing process does not require hybridoma, mRNA, or other sequence information. It provides a direct and independent insight into your antibody sample.

Accurate – We guarantee at least 5X coverage of CDRs in the variable regions. Every amino acid in the CDRs is confidently supported by fragment ions in at least five MS2 scans. For isomeric Leu and Ile, we strive to make correct inference from enzyme specificity and statistics in antibody database.

Comprehensive – As an option, we offer comprehensive characterization of the antibody protein. Our service includes the analyses of PTMs, glycosylation, disulphide bridges, contaminants, and other aspects customized to your needs.

Efficient – We use minimal amount of antibody sample (0.2 mg) and deliver results within 15 business days with consistent quality.

Method

Our team specializes in protein mass spectrometry and informatics. We develop proprietary workflow and software for antibody de novo sequencing. Our standard procedure consists of the following steps.

  1. Digest the antibody protein into overlapping peptides with multiple enzymes.
  2. Analyze the digestions with LC-MS/MS using a Thermo Orbitrap mass spectrometer.
  3. Characterize overlapping peptides with de novo peptide sequencing.
  4. Automated antibody sequence assembly from characterized peptides.
  5. Result examination and annotation by our scientists.
Show less
Q Exactive Orbitrap LC-MS/MS system de novo proteomics novor Mass Spectrometry

ic

Protein Sequencing

Starting at $6,999.00 per sample
Request a quote for more information about this service.
Mass Spectrometry de novo sequencing

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Recombinant Antibody Production

Starting at $20,000.00 per sample

You provide: Monoclonal antibody sample (>0.2mg, >95% purity, >0.5mg/mL concentration, without excessive BSA or other proteins)
We deliver: 3 mg purified antibody in IgG format; QC data; Full sequence of heavy and light chains; Comprehensive sequencing report.

Money-back guarantee – We guarantee that the antibody... Show more »

You provide: Monoclonal antibody sample (>0.2mg, >95% purity, >0.5mg/mL concentration, without excessive BSA or other proteins)
We deliver: 3 mg purified antibody in IgG format; QC data; Full sequence of heavy and light chains; Comprehensive sequencing report.

Money-back guarantee – We guarantee that the antibody we produced binds to the same antigen with similar affinity as the antibody sample provided.

Service Overview

Rapid Novor offers the "Sequencing + Expression" service to deliver antibodies that works. We directly sequence the antibody protein and then make a recombinant version of it. Our service guarantees that the antibody we produced binds to the same antigen with similar affinity as the antibody sample provided.

Method

The standard "Sequencing + Expression" service consists of the following steps:

  1. Sequence the antibody protein using our proprietary antibody protein sequencing service.
  2. Gene synthesis
  3. Cloning into pUV vectors
  4. Transient transfection of HEK293 cells
  5. Affinity purification
  6. Quality control to ensure purity (>98%), low endotoxin (<1EU/mg) and no albumin contamination
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novor de novo sequencing Affinity chromatography Recombinant Mass Spectrometry

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Antibody Characterization

Price on request

You provide: Monoclonal antibody sample (>0.2mg, >95% purity, >0.5mg/mL concentration, without excessive BSA or other proteins)
We deliver: Full sequence of heavy and light chains; Full sequence coverage by LC-MS/MS; Comprehensive report; PTM and Glycosylation report (optional) and Raw LC-MS/MS data.

**Money-back... Show more »

You provide: Monoclonal antibody sample (>0.2mg, >95% purity, >0.5mg/mL concentration, without excessive BSA or other proteins)
We deliver: Full sequence of heavy and light chains; Full sequence coverage by LC-MS/MS; Comprehensive report; PTM and Glycosylation report (optional) and Raw LC-MS/MS data.

Money-back guarantee – We guarantee at least 5X coverage of the CDRs, 3X coverage for 95% of the sequence, and 1X coverage for the full length. If the target coverage is not met, you will be fully refunded.

Promotion - We will sequence the first antibody protein for new customers at half of our regular price!

Service Overview

Rapid Novor offers antibody de novo sequencing service. We directly sequence the antibody protein using multiple enzyme digestion and high resolution LC-MS/MS. Our service guarantees full length sequencing of the heavy and light chains.

Our sequencing process does not require hybridoma, mRNA, or other sequence information. It provides a direct and independent insight into your antibody sample.

Accurate – We guarantee at least 5X coverage of CDRs in the variable regions. Every amino acid in the CDRs is confidently supported by fragment ions in at least five MS2 scans. For isomeric Leu and Ile, we strive to make correct inference from enzyme specificity and statistics in antibody database.

Comprehensive – As an option, we offer comprehensive characterization of the antibody protein. Our service includes the analyses of PTMs, glycosylation, disulphide bridges, contaminants, and other aspects customized to your needs.

Efficient – We use minimal amount of antibody sample (0.2 mg) and deliver results within 15 business days with consistent quality.

Method

Our team specializes in protein mass spectrometry and informatics. We develop proprietary workflow and software for antibody de novo sequencing. Our standard procedure consists of the following steps.

  1. Digest the antibody protein into overlapping peptides with multiple enzymes.
  2. Analyze the digestions with LC-MS/MS using a Thermo Orbitrap mass spectrometer.
  3. Characterize overlapping peptides with de novo peptide sequencing.
  4. Automated antibody sequence assembly from characterized peptides.
  5. Result examination and annotation by our scientists.
Show less
Q Exactive Orbitrap LC-MS/MS system de novo proteomics novor HPLC Mass Spectrometry Show 6 more tags Show less

ic

Antibody Services

Price on request
Request a quote for more information about this service.

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Protein Services

Price on request
Request a quote for more information about this service.

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Protein Characterization

Price on request

Protein Characterization Services

Protein Characterization Services

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Monoclonal Antibody (mAb) Production

Price on request
Request a quote for more information about this service.

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