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PureHoney Technologies

11 Orders Completed
Billerica, Massachusetts, US

About PureHoney Technologies

PureHoney Technologies is a contract research organization that helps pharmaceutical and biotech discovery teams accelerate drug discovery research by enabling intractable targets. Founded by the original developers of the RapidFire MS instrumentation, PureHoney Tech uses the high-throughput mass spectrometry... Show more »

PureHoney Technologies is a contract research organization that helps pharmaceutical and biotech discovery teams accelerate drug discovery research by enabling intractable targets. Founded by the original developers of the RapidFire MS instrumentation, PureHoney Tech uses the high-throughput mass spectrometry platform to perform analyses of challenging analytes across a broad range of therapeutic areas.

PureHoney Tech applies mass spectrometry-based screening to a wide range of targets, including those with substrates such as lipids, fatty acids, phospholipids, steroids, prostaglandins, and other compounds not generally amenable to conventional screening techniques. They offer a broad range of early stage services including: enzymology and characterization of targets, custom HTS assay development, hit identification, fragment-based screening, hit validation, SAR screening and in vitro ADME sample screening.

PureHoney Technologies headquarters and screening laboratories are located in Acton, Massachusetts.

Select Publications

  • Kheng B Lim, Can C Ozbal, Daniel B Kassel, High-Throughput Mass Spectrometric Cytochrome P450 Inhibition Screening. Methods in molecular biology (Clifton, N.J.) 987:25-50, March 2013. 
  • Peter T Rye, Lauren E Frick, Can C Ozbal, William A Lamarr, Advances in Label-Free Screening Approaches for Studying Sirtuin-Mediated Deacetylation. Journal of Biomolecular Screening 16(10):1217-26, September 2011.
  • Peter T Rye, Lauren E Frick, Can C Ozbal, William A Lamarr, Advances in Label-Free Screening Approaches for Studying Histone Acetyltransferases. Journal of Biomolecular Screening 16(10):1186-95, September 2011.
  • Andrew D Wagner, Janet M Kolb, Can C Ozbal, John J Herbst, Timothy V Olah, Harold N Weller, Tatyana A Zvyaga, Wilson Z Shou, Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P‐glycoprotein (P‐gp) inhibition screen. Rapid Communications in Mass Spectrometry 25(9):1231-40, May 2011.
  • Kheng B Lim, Can C Ozbal, Daniel B Kassel, Development of a High-Throughput Online Solid-Phase Extraction/Tandem Mass Spectrometry Method for Cytochrome P450 Inhibition Screening. Journal of Biomolecular Screening 15(4):447-52, March 2010.
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Certifications & Qualifications

Agilent Service Provider

Diversity Certificates

Small business

Our Services (27)


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Cell-Based Compound Screening

Price on request

Simply send us your quenched assay plates and we’ll do the rest. We can help develop new assays or use your existing assay to screen your compound libraries quickly, efficiently and inexpensively. The expert scientists at PureHoney Tech will provide you with high-quality, label-free data in a fraction of the time required for most... Show more »

Simply send us your quenched assay plates and we’ll do the rest. We can help develop new assays or use your existing assay to screen your compound libraries quickly, efficiently and inexpensively. The expert scientists at PureHoney Tech will provide you with high-quality, label-free data in a fraction of the time required for most other label-free technologies, getting your project moving through the drug discovery pipeline.

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Fragment Screening

Price on request
  • Singleton or compressed library screening
  • Fragment-based screening
  • Singleton or compressed library screening
  • Fragment-based screening
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Mass Spectrometry Method Development

Price on request

Method development services for biochemical assays and mass spectrometric analysis.

Method development services for biochemical assays and mass spectrometric analysis.

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Assay Development

Price on request

Our scientists have analyzed millions of wells spanning a variety of challenging targets across a broad array of therapeutic areas. We are specialists in label free assay development and screening using native substrates on mass spectrometers. With more than 30 years combined experience, we can help get your investigations done... Show more »

Our scientists have analyzed millions of wells spanning a variety of challenging targets across a broad array of therapeutic areas. We are specialists in label free assay development and screening using native substrates on mass spectrometers. With more than 30 years combined experience, we can help get your investigations done fast and rich with accurate data.

You receive personalized attention and counsel working directly with one of our Ph.D.’s to develop a customized assay solution for your specified target. Mass spectrometry-based screening can be applied to a wide range of targets, including those intractable targets with substrates such as lipids, fatty acids, phospholipids, steroids, prostaglandins, and other compounds not generally amenable to conventional screening techniques.

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RapidFire Mass Spectrometry

Price on request

Our drug discovery research services are conducted using the Agilent RapidFire platform. The ability of mass spectrometry to selectively and accurately quantify native analytes directly, without the requirement of antibodies or optically active labels, allows PureHoney Tech to develop new assays for the most challenging of... Show more »

Our drug discovery research services are conducted using the Agilent RapidFire platform. The ability of mass spectrometry to selectively and accurately quantify native analytes directly, without the requirement of antibodies or optically active labels, allows PureHoney Tech to develop new assays for the most challenging of targets. The throughput and capacity of the RapidFire system enables our scientists to provide you dependable mass spectrometry based data with unparalleled turnaround times.

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HPLC-MS

High Performance Liquid Chromatography Coupled Mass Spectrometry
Price on request
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Specialty Mass Spectrometry Methods

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Liquid Chromatography Coupled Mass Spectrometry Methods

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Drug Discovery

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Project Management

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Spectroscopy

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Pharmacology & Toxicology

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Assay Plates

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Contract Research

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High Throughput Screening (HTS)

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In vitro ADME/DMPK Studies

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Mass Spectrometry

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Imaging & Spectroscopy

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Business Development, Marketing & Operations

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Business Development, Marketing & Operations Services

Business Development, Marketing & Operations Services

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Business Operations and Logistics Support

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Business Operations and Logistics Support Services

Business Operations and Logistics Support Services

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Biology

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Biology Services

Biology Services

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Pharmacology

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Pharmacology Services

Pharmacology Services

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ADME/DMPK Studies

Drug Metabolism and Pharmacokinetics
Price on request

ADME/DMPK Studies Services

ADME/DMPK Studies Services

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Needs follow up

Price on request

Needs follow up Services

Needs follow up Services

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Potentially delete

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Potentially delete Services

Potentially delete Services

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Hit Identification

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Drug Discovery & Development

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Can Ozbal

President & CEO

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