Indiana University School of Medicine Proteomics Core Facility provides protein and proteomic analysis services for protein identification, characterization, and quantification. The Core encourages collaborations that apply the tools of proteomics to cutting-edge biomedical research.
Established in 2001, the Core has become a center not only for services but also for collaborative research and development of new technological platforms for proteomic research. The Core is available to Indiana Universities and the wider research community.
Over the years, our facility has worked with many pharmaceutical and biotech companies, and developed a number of SOPs for biomarker discovery, mass spec-based protein assays, and biomarker candidate validation.
Our major platforms are label-free protein quantification for biomarker discovery and multiple-reaction-monitoring (MRM) for protein assays and biomarker validation.
Our goal is to deliver value to our investigators and our community as a world-class proteomics core lab providing services to meet the critical needs of biomedical researchers in life science industries and academia.
Bone biology: single protein assay for P1NP or P3NP, human, rat, dog
Cardiovascular diseases: multiplexed assay for 12 different apolipoproteins: ApoA1, ApoA2, ApoA4, ApoB100, ApoC1, ApoC2, ApoC3, ApoE, ApoF, ApoM, PON1, PON3
Neuroscience: multiple forms of Abeta peptides: Abeta1-37, Abeta1-39, Abeta1-40, Abeta1-42
Inflammation: single protein assay for orosomucoid
Toxicity (cardiac): multiplexed assay for FABP3, MYL3, and troponin 1
Alcoholism: multiplexed assay for ADH gamma 1 and gamma 2
Obesity/Diabetes: single assay for active and inactive Ghrelin
Others: vitamin D2/D3 LC/MS/MS-based assays
LC-MS/MS analysis for protein identification for simple protein mixture (e.g., TAP or IP sample) $120/sample
LC-MS/MS analysis for protein identification for complex protein mixture (e.g., subcellular fraction sample) $180/sample
Advanced data analysis (post-translational modification studies, differentiating isoforms, bioinformatics, and biostatistics, etc.)
MudPIT protein profiling $2,500/sample
SRM/MRM for targeted proteomic analysis / assay development (biomarker verification/validation)
Post-translational modification analysis (up to 3 sites) $1,200/sample
LC/MS-based label-free quantitative protein profiling (including statistical analysis) (for biomarker discovery) $800/sample
ICAT/iTRAQ quantitative proteomic analysis
Proteomics Core has not received any reviews.
Proteomics Core has not received any endorsements.