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Protein Expression & Purification and Macromolecular Crystallography Core Facilities

ic 8.6/10 Overall Rating 92% Positive
ic 22 Orders Completed
Chapel Hill, North Carolina, US

About Protein Expression & Purification and Macromolecular Crystallography Core Facilities

The Protein Expression & Purification (PEP) core specializes in the production of pure, functional proteins for structural, biophysical, and biochemical studies. The ability to produce and purify milligram amount of protein enables a broad array of applications and research that extend into virtually every... Show more ยป

The Protein Expression & Purification (PEP) core specializes in the production of pure, functional proteins for structural, biophysical, and biochemical studies. The ability to produce and purify milligram amount of protein enables a broad array of applications and research that extend into virtually every area of biophysical and biomedical research.

The Macromolecular Crystallography (MX) core offers services in crystal structure determination and analysis. It is closely entwined the the PEP core which is primed to produce your proteins at sufficient quantities and levels of purity for crystallographic aims.

The Protein Expression & Purification (PEP) and Macromolecular Crystallography (MX) core facilities are part of the UNC Center for Structural Biology where we are poised to offer other essential services as part of a development package, including peptide synthesis, testing and validation in biomolecular interaction assays, mass spectrometry, and more.

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Our Services (16)


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Crystal Structure Determination

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X-ray Crystallography

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Antigen Expression and Purification

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Bacterial Protein Expression

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Baculovirus/Insect Cell Protein Expression

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Recombinant Protein Expression

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Mammalian system based (293/CHO) recombinant protein production

Mammalian system based (293/CHO) recombinant protein production

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Biology

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Protein Production

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Protein Services

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Biochemistry & Molecular Biology

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Bioconjugation/Chemical Crosslinking

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Antibody Services

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Protein Purification

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Structural Biology

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Structural Biology Services

Structural Biology Services

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Protein Expression in Mammalian Cells

Mammalian cell based recombinant protein production
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Antibody Purification

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  • Positive review for Recombinant Protein Expression:

    October 2017

    "good service"

  • Positive review for Recombinant Protein Expression:

    February 2016

    "Working with Protein Expression And Purification Core Facility is a real pleasure in terms of scientific excellence and human and social relationship. Thank you Mike and all the group for your great work. We will get back to you soon for another project. I strongly recommend this lab for Protein Expression and Purification. All the best Sonia"

  • Positive review for Recombinant Protein Expression:

    April 2015

    "W e are very much satisfied, it is with great pleasure to work again and again with Michael Miley at Protein Expression and Purification Core Facility. Very professional work, and fruitful experience. I highly recommend this wonderful team for any work with Protein Expression and Purification."

  • Positive review for Protein Expression in Mammalian Cells:

    April 2014

    "Thank you Michael for the great work on this project, it is a pleasure to continue working with you again, we particularly appreciate your prompt reply and your precious advices and recommendations regarding this project. Your contributions make a real difference."

Protein Expression & Purification and Macromolecular Crystallography Core Facilities has not received any endorsements.