The Protein Expression & Purification (PEP) core specializes in the production of pure, functional proteins for structural, biophysical, and biochemical studies. The ability to produce and purify milligram amount of protein enables a broad array of applications and research that extend into virtually every area of biophysical and biomedical research.
The Macromolecular Crystallography (MX) core offers services in crystal structure determination and analysis. It is closely entwined the the PEP core which is primed to produce your proteins at sufficient quantities and levels of purity for crystallographic aims.
The Protein Expression & Purification (PEP) and Macromolecular Crystallography (MX) core facilities are part of the UNC Center for Structural Biology where we are poised to offer other essential services as part of a development package, including peptide synthesis, testing and validation in biomolecular interaction assays, mass spectrometry, and more.
Mammalian system based (293/CHO) recombinant protein production
"The Protein Expression & Purification and Macromolecular Crystallography Core Facilities at UNC has done an awesome job for us. High quality proteins were produced in a timely manner. Communications were smooth and professional. Highly recommended!"
"We had a great experience working with the PEP core. John offered very valuable advice, was great at keeping us updated on the progress of the project, and produced a high quality product. Would highly recommend."
"Working with Protein Expression And Purification Core Facility is a real pleasure in terms of scientific excellence and human and social relationship. Thank you Mike and all the group for your great work. We will get back to you soon for another project. I strongly recommend this lab for Protein Expression and Purification. All the best Sonia"
"W e are very much satisfied, it is with great pleasure to work again and again with Michael Miley at Protein Expression and Purification Core Facility. Very professional work, and fruitful experience. I highly recommend this wonderful team for any work with Protein Expression and Purification."
"Thank you Michael for the great work on this project, it is a pleasure to continue working with you again, we particularly appreciate your prompt reply and your precious advices and recommendations regarding this project. Your contributions make a real difference."
Protein Expression & Purification and Macromolecular Crystallography Core Facilities has not received any endorsements.