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Protavio Ltd - The art in multiplex assays

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Attica, GR

About Protavio Ltd - The art in multiplex assays

Founded: 2012 Type: Privately Held Size: 1-10 employees

**Protavio offers services  specific to COVID-19 research. Submit a quote request containing the word ‘COVID-19’ to receive more details.**

Protavio is a drug and biomarker discovery solutions provider for the pharmaceuticals, diagnostics and life sciences sectors. Using advanced in-vitro and in-silico approaches and proprietary technology, we deliver fast and experimentally proven services for compound evaluation (target identification, efficacy, toxicity, mode-of-action, drug repositioning) and biomarker discovery and performance analysis. Our expertise on the development of multiplex assays can be leveraged throughout the development pipeline of therapeutics and vaccines from the analysis of clinical samples or serological responses to the development of in-vitro and companion diagnostics. Our happy customers, our strong publication record, and our two international awards guarantee a unique high quality service.

Our Services (13)


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Cell-Based Compound Screening

Price on request

New generation HTS is performed with custom assays using automated procedures. We offer an A-to-Z service including:
i) 50+ disease models (primary and cell lines) in 96 well plates,
ii) compound treatment using custom or commercial libraries,
iii) sample preparation,
iv) Assays using Luminex multiplex technologies + High Content Screening + Transcriptomics
v) Computational Data analysis

Applications:
Compound Mode-of-Action
Efficacy
Toxicity
Drug Repositioning
Competition Drugs

Capacity: Our facility can process 1000s samples per day using the largest multiple panels in the market.

Recognition: Our computational analysis has been published in top journals and ranges from data visualization all the way to identification of drug mode of action, drug repositioning, pathway construction, prediction of efficacy etc. See examples here: www.protavio.com

Toxicology Luminex FLEXMAP 3D Biology Drug Discovery alphaLISA Luminex® Human Rat Mouse Oncology Cardiovascular Hepatology signal transduction pathway analysis Fibrotic Disease Nephrology and Urology Metabolism and Endocrinology Show 16 more tags Show less

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Immunoassays

Price on request

Service Description:
Protavio has extensive experience in the provision of multiplex immunoassays using the xMAP Luminex technology. We run your samples in our GMP-compliant state-of-the art facilities using top-end equipment and fully-trained scientific personnel. You can select from our existing disease and species panels or request customised assay development.

Analytes/Targets: For our existing in-house panels visit: https://www.protavio.com/order-now or check our white paper on "Biomarker Panels".
Instrumentation: FlexMAP 3D & Luminex 200
Turnaround time: 4-8 weeks depending on project requirements.
Deliverables: Results report containing measurements of relative quantitation (MFI) or absolute values (when standards are available).

Prices depend on the project needs and the target analyte panel required, feel free to request for a quote.

Immuno-Oncology Metabolism and Endocrinology Neurodegenerative diseases Chronic obstructive pulmonary disease (COPD) Asthma Fibrotic Disease Luminex FLEXMAP 3D Luminex® Biology Drug Discovery antibodies Blood Serum Biofluids Human Mouse Rat Oncology Immunology Respiratory Nephrology and Urology Cardiovascular signal transduction pathway analysis Show 23 more tags Show less

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Luminex Assay Development

Price on request

ISO13485 compliant production. Protavio is a Luminex Partner and has extensive experience in the development of multiplex assays using the xMAP technology.
Service Description:
Instrumentation: FlexMAP 3D & Luminex 200
Turnaround time: 4-8 weeks depending on project requirements.
Deliverables: Assay Reagents and Standards for 10x 96-well plates for customised assays. Full report on Assay Information and performance is included.

For more information on sample requirements and our assay development process visit: https://www.protavio.com/custom-plex

Prices are per analyte/target to be quantified for 10x 96-well plates (approximately 800 samples). For smaller projects/sample sizes, contact us at [email protected].

Asthma Pulmonary fibrosis Neurodegenerative diseases Immuno-Oncology Autoimmune disease Luminex FLEXMAP 3D Luminex® Biology Drug Discovery Immunoassays antibodies Blood Serum Frozen Tissue FFPE tissue Biofluids Mouse Rat Oncology Metabolism and Endocrinology Immunology Nephrology and Urology Cardiovascular Show 23 more tags Show less

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Biomarker Discovery

Price on request

Protavio offers biomarker discovery services using both dedicated target panels and custom panels tailored to your needs.
Targets/Analytes: Select from our existing panels or create your own using our custom services: www.protavio.com/order-now

Instrumentation: FlexMAP 3D & Luminex 200
Sample requirements: Blood, serum, urine, cell supernatants, cell lystaes, cerebrospinal fluid, BALF, solid tissues, tissue sections.
Turnaround time: 4-8 weeks depending on project needs.
Deliverables: - Full results report containing method specifications, relative (MFI) or absolute (pg/mL) measurements
- Analysis of biomarker performance (ROC, PCA, clustering, machine learning).

Different prices apply depending on the target panel and number of samples. Find more on our pricing by asking for a quote.

Luminex® Neurodegenerative diseases Acute Kidney Injury Fibrotic Disease Asthma Immuno-Oncology Autoimmune disease Luminex FLEXMAP 3D Biology Drug Discovery antibodies Blood Serum Biofluids Human tissue FFPE tissue Human Rat Mouse Oncology Immunology signal transduction pathway analysis Metabolism and Endocrinology Cardiovascular Nephrology and Urology Hepatology CNS/Neurology Show 27 more tags Show less

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Biomarker Analysis

Price on request

This service will help you draw meaningful conclusions on a biomarker's ability to become a diagnostic tool (distinguish between healthy and disease states), a predictive tool (the probable effect of treatment on the disease), or prognostic biomarker (how a disease may develop regardless of treatment). Biomarker performance can be assessed individually (one biomarker at a time) or as a panel (optimal 3 plex).

Methods: Our bioinformatics team will use several methods including ROC analysis, PCA, clustering, and advanced machine learning techniques to select the best biomarkers.

Deliverables: Scientific report containing results from performance analysis, various visualisation formats of data (box plots, heat maps, etc), selection of best performing biomarkers and literature search of tope performing biomarkers.

Prices are approximate and depend on size of study.

Acute Kidney Injury Asthma Fibrotic Disease Chronic obstructive pulmonary disease (COPD) Immuno-Oncology Bioinformatics Computational systems biology Systems biology Human Mouse Rat Oncology Respiratory Metabolism and Endocrinology Cardiovascular Nephrology and Urology Immunology signal transduction pathway analysis Show 18 more tags Show less

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Drug Discovery

Price on request

New generation HTS is performed with custom assays using automated procedures. We offer an A-to-Z service including:
i) 50+ disease models (primary and cell lines) in 96 well plates,
ii) compound treatment using custom or commercial libraries,
iii) sample preparation,
iv) Assays using Luminex multiplex technologies + High Content Screening + Transcriptomics
v) Computational Data analysis

Applications:
Compound Mode-of-Action
Efficacy
Toxicity
Drug Repositioning
Competition Drugs

Capacity: Our facility can process 1000s samples per day using the largest multiple panels in the market.

Recognition: Our computational analysis has been published in top journals and ranges from data visualization all the way to identification of drug mode of action, drug repositioning, pathway construction, prediction of efficacy etc.

See more at: https://www.protavio.com/compound-evaluation


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Computational Modeling

Price on request

Computational & Statistical Analysis Services


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Bioinformatics

Price on request
Request a quote for more information about this service.

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Project Management

Price on request

Project Management & Consulting Services


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Hit Identification

Price on request
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Pharmacology & Toxicology

Price on request
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In vitro Cardiotoxicity Screening

Price on request
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Data Services

Price on request
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