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Prodrome Sciences Inc.

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Carlsbad, California, US

About Prodrome Sciences Inc.

A disease prodrome is the dysfunctional biochemical state that appears in your body before you get a disease. Contained within each disease prodrome is the causation of that disease. At Prodrome Sciences Inc., we focus on understanding everything there is to know about disease prodromes – how to detect them,... Show more »

A disease prodrome is the dysfunctional biochemical state that appears in your body before you get a disease. Contained within each disease prodrome is the causation of that disease. At Prodrome Sciences Inc., we focus on understanding everything there is to know about disease prodromes – how to detect them, what causes them, and how to return them back to a healthy state. Prodrome Sciences develops ways to identify prodromes using our advanced diagnostic technology. This detection platform is applied in our disease prodrome diagnostic tests and in our natural human molecule therapeutic programs to restore a prodrome state to a healthy, low-risk state.

Key Publications

  • Breitling R, Ritchie S, Goodenowe D, Stewart ML, Barrett MP. Ab initio prediction of metabolic networks using Fourier transform mass spectrometry data. Metabolomics. 2006;2(3):155-164.
  • Zulak KG, Cornish A, Daskalchuk TE, Deyholos MK, Goodenowe DB, Gordon PM, Klassen D, Pelcher LE, Sensen CW, Facchini PJ. Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism. Planta. 2007 Apr;225(5):1085-106.
  • Reduced levels of hydroxylated, polyunsaturated ultra-long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection (BMC Medicine 2010, 8:13).
  • Metabolic system alterations in pancreatic cancer patient serum: potential for early detection (BMC Cancer 2013, 13:416).
  • Yamazaki M, Mochida K, Asano T, Nakabayashi R, Chiba M, Udomson N, Yamazaki Y, Goodenowe DB, Sankawa U, Yoshida T, Toyoda A, Totoki Y, Sakaki Y, Góngora-Castillo E, Buell CR, Sakurai T, Saito K. Coupling deep transcriptome analysis with untargeted metabolic profiling in Ophiorrhiza pumila to further the understanding of the biosynthesis of the anti-cancer alkaloid camptothecin and anthraquinones. Plant Cell Physiol. 2013 May;54(5):686-96.
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Our Services (4)


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Metabolite Profiling

Price on request

Non-targeted, discovery metabolomics for pharma, biotech, food industry, and academia. We can analyze plasma, serum, tissues, cells, organelles, cell culture material, fecal samples, plant material, bacterial and yeast cultures, environmental samples, food samples (food ingredients, functional foods, nutraceuticals, etc.) on our... Show more »

Non-targeted, discovery metabolomics for pharma, biotech, food industry, and academia. We can analyze plasma, serum, tissues, cells, organelles, cell culture material, fecal samples, plant material, bacterial and yeast cultures, environmental samples, food samples (food ingredients, functional foods, nutraceuticals, etc.) on our accurate mass high resolution mass spectrometry platform. Six different analytical modes will analyze for Ionic bases, ionic acids/glucuronides, polar bases/neutrals, polar acids/neutrals, non-polar bases/neutrals, non-polar acids/neutrals. Typically, we can identify more than 10000 unique metabolites, based in the accurate mass, from human serum sample. This platform has been used to develop biomarker platforms/screening tests for various cancers and neurological diseases, to identify changes to metabolic pathways due to genetic manipulations, to study bioactive plants and to identify metabolic alterations resulting from gut microbial changes etc.

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Metabolomics

Price on request

Non-targeted, discovery metabolomics for pharma, biotech, food industry, and academia

Prodrome Sciences’ customizable, non-targeted, comprehensive metabolomic platform is now available for contract research services. Our patented complex sample analysis technology was invented in 1999, patented in 2000, and commercialized in... Show more »

Non-targeted, discovery metabolomics for pharma, biotech, food industry, and academia

Prodrome Sciences’ customizable, non-targeted, comprehensive metabolomic platform is now available for contract research services. Our patented complex sample analysis technology was invented in 1999, patented in 2000, and commercialized in 2001. Since 2001, tens of thousands of biospecimens encompassing hundreds of independent experimental designs have been performed. The data generated using the technology has resulted in numerous patents, peer-reviewed publications, and regulatory-approved diagnostics products.

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Omics

Price on request

Omics Services

Omics Services

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Biology

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Biology Services

Biology Services

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Erika Shklanka

VP, Operations

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