Pharmaron (Stock Code: 300759.SZ/3759.HK) is a leading fully-integrated pharmaceutical R&D service platform supporting the life science industry. Founded in 2004, Pharmaron has invested in its people and facilities and established its comprehensive service offerings throughout the pharmaceutical R&D life cycle. With operations in China, US and UK staffed by over 7,500 employees, Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan and China. For more information: www.pharmaron.comKey highlights of Pharmaron’s diverse R&D service capabilities: • Synthetic, medicinal and analytical chemistry • in vitro and in vivo Biology • ADME/DMPK • Pharmacology • Drug safety assessment • Radiochemistry and isotopically labelled metabolism • Chemical & pharmaceutical development • Clinical development, including applications of 14C microtracer AMS technology
Drug safety issue is a major reason for drug attrition. Pharmaron offers a comprehensive panel of in vitro safety screening services to help identify drug safety issues at the early stage of drug discovery. A team of well-trained scientists with the state-of-the-art technologies allow for high quality data to be generated rapidly and cost-effectively. We offer both standardized and customized services. Our in vitro safety screening services can be contracted individually or combined with Chemistry, in vitro ADME and Biology as part of a fully integrated program.
Non-high content safety screening
High content safety screening
Ion Channel safety screening
Gene sequence or analysis (DNA / RNA)
Gene expression, mutation, regulation
Protein expression and modification
Immune cell activation analysis on PBMC or lymph tissue
Pharmaron offers comprehensive in vivo pharmacokinetic (PK), toxicokinetics, GLP bioanalytical (for detail for GLP and GCP bioanalytical services, please see Safety Assessment / GLP/GCP Bioanalytical Services), discovery bioanalytical, and formulation services to our partners. All in-life work of PK/TK studies are conducted in AAALAC-approved animal facilities and follow IACUC-approved study protocols. We offer high quality (FDA/OECD/EPA accepted) and fast turnaround GLP and non-GLP bioanalytical services to support drug discovery, pre-clinical and clinical development for small molecules, peptides, nucleosides/nucleotides and biologics. Our formulation services are offered either as part of the PK study or as a standalone service.
In vitro Biology
Pharmaron Biology provides a spectrum of high quality services to support various stages of drug discovery and development. With state-of-the art facilities and instrumentation, proprietary data management systems – CEDAR™, we offer services in assay development, compound screening, PD/biomarkers, bioreagents and structural biology, and in vitro toxicity.
We have a team of experienced scientists that are familiar with drug discovery processes, and understand how and where biology services can help our clients succeed in target validation, hit identification, hit to lead, lead optimization, and selection of preclinical candidates. These services are provided either as standalone services, or as a part of integrated projects that also include components such as medicinal chemistry, DMPK, in vivo pharmacology and toxicology.
Pharmaron has established a state-of-the-art compound management system with the following features:
Industry-leading software (Mosaic)
Barcode scanning at all levels
Tight climate control
Secured compound storage
Dedicated UPS in labs
Drug Metabolism and Pharmacokinetics
Rodent and large animal PK studies in Beijing
Drug Metabolism and Pharmacokinetics
in vitro ADME assays in Beijing
Synthesis of 3H and 14C labeled compounds and radiolabeled metabolism studies
With strong training in biochemistry, molecular and cellular biology, our teams are highly experienced, and focused on customer assay development, compound evaluation using cell-free biochemical assays, cell culture models, and biomarker discovery.
"Great experience. They meet or beat the timelines and the compound purity is great."
"Did great job"
"Pharmaron did very good job in delivery of high-quality on time. When I have some question for the data, they replied in a timely fashion, and perform trouble shooting and assay optimization accordingly."
"Excellent service, very high quality, great employees"
"My experience was excellent. Pharmaron showed great flexibility and speed. The data quality was excellent. I would continue to work with Pharmaron any time and would recommend to colleagues without hesitation. Thanks for all the support you provide to our projects! I also appreciate your friendliness and professionalism. Best regards, Maria"
Pharmaron, Inc. has not received any endorsements.