PEPperPRINT GmbH
10.0/10 Overall Rating
100% Positive
10 Orders Completed
Heidelberg, DE
PEPperPRINT is a young and innovative biotech company based in Heidelberg, Germany, and a spin-off of the German Cancer Research Center. We provide the new peptide microarray platform PEPperCHIP® for: - Antigen and Epitope Discovery - Epitope Mapping - Epitope Substitution Scans - Immune Monitoring of Anti-Drug Antibodies - Vaccine and Adjuvant Development - Complicance Marker Discovery and Development - Serum Biomarker Discovery - Peptide Target Binder Discovery and Development With our proprietary peptide laser printing technology, the high-density PEPperCHIP® Microarrays set a new standard in terms of peptide diversity, signal quality and content flexibility.
Antibodies are among the most important life science tools for therapeutics, basic research and diagnostic tests. However, mono- and polyclonal antibodies are often poorly characterized in terms of epitope and antigen knowledge, specificity and cross-reactivity.
To address these topics, PEPperPRINT developed a number of disruptive solutions for the in-depth analysis of epitopes, antibodies and antibody cross-reactions with all kinds of samples, antibody isotypes and species in the most flexible, comprehensive and economic manner. These solutions cover a range of applications for e.g.
Specifications of PEPperMAP® Linear Epitope Mapping (975€)
The PEPperMAP® Linear Epitope Mapping is the standard epitope mapping format based on a single peptide length and the maximum peptide overlap for high resolution epitope data. The PEPperMAP® Linear Epitope Mapping is the recommended solution for monoclonal antibodies and serum samples.
Specifications of PEPperMAP® Conformational Epitope Mapping (1995€)
High resolution PEPperMAP® Conformational Epitope Mapping is based on an antigen translated into 7, 10 and 13 aa cyclic constrained peptides with max. peptide overlaps of 6, 9 and 12 aa. Different peptide lengths are applied to mimic different loop sized and hence epitope conformations.
From single antigens translated into overlapping peptides to whole virus proteomes – PEPperCHIP® Custom Peptide Microarrays can be fully tailored in a uniquely cost-effective manner.
Peptide Synthesis: On-chip using Fmoc chemistry and rountine double coupling steps
Microarray Format: Standard slide format (3'' x 1'', 75.4 mm x 25.0 mm x 1.0 mm)
Number of Peptides: From 130 to 5,500 different peptides printed in duplicate
Assays per Microarray: From single arrays to 16 arrays per chip depending on the number of peptides
Array Content: Fully flexible with custom protein-derived overlapping peptides, peptide collections, substitution scans etc.
Available Amino Acids: L- and D-amino acids, citrulline and other amino acids on request
Peptide Length: Rountine synthesis of up to 15mer peptides, longer peptides on request
Control Peptides: Standard HA (YPYDVPDYAG) and Flag (DYKDDDDKAS) tags, other controls on request
PEPperCHIP® Custom Peptide Microarray (895€)
PEPperCHIP® Custom Cyclic Peptide Microarray (995€)
Optional add-on services or products:
Beside custom PEPperCHIP® Peptide Microarrays, we also provide PEPperCHIP® Standard Peptide Microarrays with off-the-shelf content for infectious disease, allergen, cancer and autoimmune research.
PEPperCHIP® Standard Peptide Microarrays cover selected epitopes, antigens or whole viral proteomes translated into overlapping peptides, or random peptide libraries for signature discovery.
PEPperCHIP® Peptide Microarrays for Autoimmune Research
PEPperCHIP® Peptide Microarrays for Cancer Research
PEPperCHIP® Peptide Microarrays for Allergen Research
PEPperCHIP® Peptide Microarrays for Infectious Disease Research
PEPperCHIP® Peptide Microarrays for Signature Discovery
Antibodies are among the most important life science tools for therapeutics, basic research and diagnostic tests. However, mono- and polyclonal antibodies are often poorly characterized in terms of epitope and antigen knowledge, specificity and cross-reactivity.
In order to address these topics, PEPperPRINT developed a number of disruptive solutions for the in-depth analysis of epitopes, antibodies and antibody cross-reactions with all kinds of samples, antibody isotypes and species in the most flexible, comprehensive and economic manner. These solutions cover a range of applications for e.g.
Specifications of PEPperMAP® Linear Epitope Mapping (975€)
The PEPperMAP® Linear Epitope Mapping is the standard epitope mapping format based on a single peptide length and the maximum peptide overlap for high resolution epitope data. The PEPperMAP® Linear Epitope Mapping is the recommended solution for monoclonal antibodies and serum samples.
Specifications of PEPperMAP® Conformational Epitope Mapping (1995€)
High resolution PEPperMAP® Conformational Epitope Mapping is based on an antigen translated into 7, 10 and 13 aa cyclic constrained peptides with max. peptide overlaps of 6, 9 and 12 aa. Different peptide lengths are applied to mimic different loop sized and hence epitope conformations.
Specifications of PEPperMAP® Antibody Cross-Reactivity Analysis (2695€)
Epitome-wide profiling of antibody cross-reactions including a bioinformatic analysis of common motifs and antibody specificity
Specifications of PEPperMAP® Epitope Substitution Scan (1395€)
Epitope Single Substitution Scans cover the stepwise substitution of all amino acid positions of a given epitope or peptide with all 20 main amino acids and optionally additional non-natural amino acids.
PEPperPRINT provides synthetic peptides for various applications like ELISA tests, competition assays, antibody generation, immunizations, the characterization of protein interaction sites, spotting and affinity purification.
Custom Peptide Synthesis - Specifications:
The identification of early biomarkers for severe diseases by noninvasive methods is very important but demanding. In this regard high-content peptide microarrays provide a very efficient tool for antibody biomarker discovery from sera. The flexibility of the PEPperCHIP® platform allows the step-wise screening from e.g. 35,000 peptides for hit discovery down to handful peptides for hit validation.
Specifications
Array content: PEPperCHIP®Custom /Standard Peptide Microarray or PEPperCHIP® Discovery Microarray with random, pre-selected or overlapping peptides
Input Data & Sample Material
Analysis
PEPperCHIP® analysis is straightforward and can be performed in your own lab or covered by our PEPperMAP® Service.
The identification of early biomarkers for severe diseases by noninvasive methods is very important but demanding. In this regard high-content peptide microarrays provide a very efficient tool for antibody biomarker discovery from sera. The flexibility of the PEPperCHIP® platform allows the step-wise screening from e.g. 35.000 peptides for hit discovery down to handful peptides for hit validation.
Specifications
Array content: PEPperCHIP®Custom /Standard Peptide Microarray or PEPperCHIP® Discovery Microarray with random, pre-selected or overlapping peptides
Input Data & Sample Material
Analysis
PEPperCHIP® analysis is straightforward and can be performed in your own lab or covered by our PEPperMAP® Service.
"It was really great experience working with PepperPrint through the Science Exchange. Timely and clear communications, reasonable time-lines, high quality data."
PEPperPRINT GmbH has not received any endorsements.