Otava Research Institute, cooperating with leading Ukrainian research institutions, carries out research work in the format of outsourcing. The research team includes chemists, biologists, physicists whose combined efforts contribute to the complex contract research projects for customers from Western Europe, North America and Japan. We work as a preferred partner to many of the world’s top 10 pharma firms, and hundreds of other companies, providing support with creative solutions for complex technical compound issues. Our scientific knowledge, combined with our research and manufacturing capability, enables us to support chemical processing and production without ever compromising on quality.
Otava RDC develops molecular probes to discover and validate therapeutic drug targets, enzyme inhibitors, biological receptor antagonists and agonists, performs pharmacophore modeling, molecular docking, molecular dynamics simulations, SAR studies.
Targeted-focused libraries comprise compounds with in silico predicted affinity to different molecular targets (G-protein coupled receptors, protein kinases, proteases, ion channels, epigenetic targets, nuclear receptors and others). In order to design targeted libraries Otava RDC applies various computational structure-based and ligand-based methods.
OtavaRD offers custom synthesis of organic molecules for pharmaceutical and biotech projects:
Template selection, sequence alignment and model generation.
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