1339457798000

Organic Synthesis Core Facility (OSCF)

New York, New York, US

The GMP compliant Organic Synthesis Core Facility (OSCF) mission is to provide chemical synthesis work.

Organic Synthesis Core Facility (OSCF) has not listed any services.

Compound Purification
Price on request

Activity-based purification of active intermediates from extracts, and scale up purification of active intermediates.

Activity-based purification of active intermediates from extracts, and scale up purification of active intermediates.

« Show less
Structure Determination
Price on request
Request a quote for more information about this service.
Chemical Synthesis
Price on request

The synthesis of modified and unmodified compounds in amounts that permit their availability for in vitro and in vivo assays and for secondary assays.

Some of the modifications that could be introduced will address such properties of molecules to render them more versatile. More precisely, we could introduce alterations that... Show more »

The synthesis of modified and unmodified compounds in amounts that permit their availability for in vitro and in vivo assays and for secondary assays.

Some of the modifications that could be introduced will address such properties of molecules to render them more versatile. More precisely, we could introduce alterations that improve solubility, affinity, and specificity.

Large-scale chemical synthesis of compounds with demonstrated activity in primary bioassays in order to provide sufficient quantities for continued testing.

Fluorescent Labeling
The synthesis of assay development tools and reagents:
-Fluorescently labeled compounds
-Affinity labeled intermediates
-Cross linker-tethered molecules

« Show less
gram
milligram
Radiolabeling/Radiosynthesis
Price on request
Request a quote for more information about this service.
DNA Synthesis and Probe Development
Price on request

Synthesis of modified nucleosides, nucleotides, as well as modified oligonucleotides (modified siRNAs, miRNAs, and damaged synthetic DNA).

Synthesis of modified nucleosides, nucleotides, as well as modified oligonucleotides (modified siRNAs, miRNAs, and damaged synthetic DNA).

« Show less
Molecular Dynamics Simulations
Price on request

Molecular modeling, homology modeling, and “in-silico” screening of virtual chemical libraries. This is backed by follow up organic synthesis of hits.

Molecular modeling, homology modeling, and “in-silico” screening of virtual chemical libraries. This is backed by follow up organic synthesis of hits.

« Show less
QSAR Studies
Quantitative Structure-Activity Relationship Studies
Price on request

Perform structure-activity relationship (SAR) studies on validated pharmacophores to optimize targeting, specificity, bioavailability, while minimizing toxicity.

Perform structure-activity relationship (SAR) studies on validated pharmacophores to optimize targeting, specificity, bioavailability, while minimizing toxicity.

« Show less
Radiotracers and Radiopharmaceuticals
Price on request

Precursors for radio-labeling experiments, as well as radio-labeled (11C, 3H, 125I, 32P …etc.) compounds for preclinical and clinical pharmacological evaluations.

Precursors for radio-labeling experiments, as well as radio-labeled (11C, 3H, 125I, 32P …etc.) compounds for preclinical and clinical pharmacological evaluations.

« Show less
MicroRNA (miRNA) Synthesis
Price on request

Synthesis of modified nucleosides, nucleotides, as well as modified oligonucleotides (modified siRNAs, miRNAs, and damaged synthetic DNA).

Synthesis of modified nucleosides, nucleotides, as well as modified oligonucleotides (modified siRNAs, miRNAs, and damaged synthetic DNA).

« Show less
Biology
Price on request
Request a quote for more information about this service.
Biochemistry & Molecular Biology
Price on request
Request a quote for more information about this service.
Nucleic Acid Services
Price on request
Request a quote for more information about this service.
DNA Services
Price on request
Request a quote for more information about this service.
RNA Services
Price on request
Request a quote for more information about this service.
Chemistry and Materials
Price on request
Request a quote for more information about this service.
Radiochemistry
Price on request
Request a quote for more information about this service.
Synthetic Chemistry
Price on request
Request a quote for more information about this service.
Computational Chemistry
Price on request
Request a quote for more information about this service.
Analytical Chemistry Services
Price on request
Request a quote for more information about this service.
Separation/Purification Services
Price on request
Request a quote for more information about this service.
Computational Modeling
Price on request
Request a quote for more information about this service.

Organic Synthesis Core Facility (OSCF) has not received any ratings.

Be the first to endorse Organic Synthesis Core Facility (OSCF)

Endorse this lab