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OmicScouts GmbH

11 Orders Completed
Freising, DE

About OmicScouts GmbH

OmicScouts is a chemical proteomics company focused on supporting drug and biomarker discovery with its unique expertise and innovative technologies.

Founded by leading proteomics researchers, the company has a track record in delivering significant collaborations with top pharmaceutical and biotechnology companies.

We provide and develop proteome-wide assays that work with native proteins in a physiological setting and enable the identification of small molecule drug targets, target engagement markers, molecular mechanisms of action and drug response biomarkers.

OmicScouts supports your drug and biomarker discovery projects with end-to-end solutions tailored to project specific needs.

Our Services (39)


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Proteomics

Price on request

OmicScouts' technologies enable informed decisions at different stages of the drug discovery process. Generally, our technologies support both traditional, target-based drug discovery and phenotypic, chemical genetics-based drug discovery.

  • The chemical proteomics TargetScout™ technology and proteome-wide CETSA® MS reveal and verify specific cellular targets, determine target-specific dissociation constants in a physiological setting, and provide selectivity information and on-/off-target liabilities
  • ProteomeScout™ provides a quantitative in-depth view of the proteome and supports the identification and selection of potential drug targets, PD and drug response biomarkers
  • Proteome-wide, quantitative profiling of post-translational modifications such as phosphorylation, ubiquitinylation or acetylation using the SignallingScout™ technology reveals target engagement information and on-/off-pathway liabilities


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Biomarker Discovery

Price on request

OmicScouts' technologies enable both unbiased biomarker discovery approaches and targeted biomarker discovery/development applications, thereby supporting the translation of basic science into applied clinical research.

  • The ProteomeScout™ technology enables unbiased identification of biologically and clinically relevant biomarkers by combining expert knowledge in sample preparation with shot-gun proteomics (LC-MS/MS) tailored to the project-specific requirements
  • In concert with complementary molecular profiling technologies, such as genomics, our quantitative proteomics technologies enable the identification of disease mechanisms, therapy response markers, companion diagnostics tools as well as potential biomarkers for prognosis and/or diagnosis
  • To facilitate the transition from discovery to application, the BiomarkerScout™ technology provides a targeted mass spectrometry approach towards biomarker discovery and, furthermore, allows the development of flexible, rapid and sensitive assays for biomarker verification
  • Targeted assays can be setup within weeks to months for all kinds of protein classes such as drug metabolism enzymes, cytokines, peptide hormones, oncogenes, kinases, immuno-oncology-related proteins, pathways and signalling sign-posts


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Systems Pharmacology

Price on request

OmicScouts' technologies provide access to various kinds of system level information in 100s of samples from different conditions, tissues and/or organisms.

  • ProteomeScout™ provides a quantitative in-depth view of the proteome. Data from 100s of samples can be used to identify systematic changes on the protein level and gain insight into disease mechanisms
  • The SignallingScout™ technology is applied for proteome-wide, quantitative profiling of post-translational modifications such as phosphorylation, ubiquitinylation, or acetylation and provides an additional layer of information to further characterize a biological system
  • Data from different proteomics experiments, as well as data from other high-throughput experiments such as Whole-Genome Sequencing or RNA-Seq, can be integrated using sophisticated in silico methods, for example machine learning approaches or network analyses


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Immuno-oncology Assays

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Precision proteomics at the interface of immunology and oncology

  • Targeted analysis of immuno-oncology biomarkers to gain a better understanding of the interplay between the immune system and tumors, to assess therapeutic efficacy and provide a basis for patient stratification (BiomarkerScout™)
  • System-wide analysis of tumor genomes and proteomes to identify unique immuno-oncology targets for antibody-based therapeutics (KinomeScout™, ProteomeScout™, proteogenomics solutions)
  • Comprehensive study of cell surface proteins, secreted and glycosylated proteins to identify potential immuno-oncology targets, novel potential targets for antibody drug conjugate (ADC) cancer therapy or markers for patient stratification (ProteomeScout™, secretome and glycoproteome analysis)


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Phosphoproteomics

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Drug Target Identification

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Drug Mechanism of Action Studies

Mechanism of Action Studies
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Multiomics

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Histone Deacetylase (HDAC) Assays

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Lead Identification and Validation

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Lead Identification and Validation Services


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Medicinal Chemistry

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Medicinal Chemistry Services


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Drug Discovery

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Drug Discovery Services


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Drug Discovery & Development

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Drug Discovery & Development Services


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Omics

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Omics Services


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Hydrolase Assays

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Hydrolase Assays Services


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Enzyme Assays

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Enzyme Assays Services


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Biochemical Assays

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Biochemical Assays Services


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Biochemistry & Molecular Biology

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Biochemistry & Molecular Biology Services


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Biology

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Biology Services


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Biomarkers

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Biomarkers Services


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Bioanalysis

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Bioanalysis Services


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Pharmacology & Toxicology

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Pharmacology & Toxicology Services


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Immunoassays

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Immunoassays Services


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Bioanalytical Assays

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Bioanalytical Assays Services


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Mass Spectrometry-Based Proteomics

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SILAC

Stable Isotope Labeling by Amino Acids in Cell Culture
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Quantitative Proteomics

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Protein Identification

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Protein Services

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Protein Services


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Protein Characterization

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Protein Characterization Services


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Peptide Mass Fingerprinting

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Protein Sequencing

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Protein Sequencing Services


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Compound Profiling

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Cytokine Analysis

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Pharmacology

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Pharmacology Services


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Isotope Coded Affinity Tagging (ICAT)

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Proteomics Data Analysis

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Label Free Quantitative Proteomics

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Kinase Assays

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