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omics2view.consulting GbR

Kiel, DE

omics2view.consulting GbR was founded in 09/2015 and is based in Kiel, Northern Germany. We are an expert company providing bioinformatic and biostatistical analysis of large high-throughput sequencing data as a scientific service.

As a spin-off from academia, we are utterly convinced that the analysis of data should be as individual as the ideas behind the scientific projects they originate from. Only then the results – when carefully arranged to meet the needs of the audience – can tell compelling stories.

This is why omics2view.consulting GbR is among the first companies to offer fully customized data analysis services with publication-ready statistics, tables, and figures tailored to the requirements of our clients.

Recent Publications

  • Mensch B, Neulinger SC, Graiff A, Pansch A, Künzel S, Fischer MA, Schmitz RA. 2016. Restructuring of epibacterial communities on Fucus vesiculosus forma mytili in... Show more »

omics2view.consulting GbR was founded in 09/2015 and is based in Kiel, Northern Germany. We are an expert company providing bioinformatic and biostatistical analysis of large high-throughput sequencing data as a scientific service.

As a spin-off from academia, we are utterly convinced that the analysis of data should be as individual as the ideas behind the scientific projects they originate from. Only then the results – when carefully arranged to meet the needs of the audience – can tell compelling stories.

This is why omics2view.consulting GbR is among the first companies to offer fully customized data analysis services with publication-ready statistics, tables, and figures tailored to the requirements of our clients.

Recent Publications

  • Mensch B, Neulinger SC, Graiff A, Pansch A, Künzel S, Fischer MA, Schmitz RA. 2016. Restructuring of epibacterial communities on Fucus vesiculosus forma mytili in response to elevated pCO2 and increased temperature levels. Front Microbiol 7.
  • Meyer J, Löscher CR, Neulinger SC, Reichel A, Loginova AN, Borchard C, Schmitz RA, Hauss H, Kiko R, Riebesell U. 2016. Changing nutrient stoichiometry affects phytoplankton production, DOP accumulation and dinitrogen fixation – a mesocosm experiment in the eastern tropical North Atlantic. Biogeosciences 13:781-794.
  • Löscher CR, Bange HW, Schmitz RA, Callbeck CM, Engel A, Hauss H, Kanzow T, Kiko R, Lavik G, Loginova AN, Melzner F, Neulinger SC, Pahlow M, Riebesell U, Schunck H, Thomsen S, Wagner H. 2015. Water column biogeochemistry of oxygen minimum zones in the eastern tropical North Atlantic and eastern tropical South Pacific Oceans. Biogeosci Discuss 12:4495-4556.
  • Löscher CR, Fischer MA, Neulinger SC, Fiedler B, Philippi M, Schütte F, Singh A, Hauss H, Karstensen J, Körtzinger A. 2015. Hidden biosphere in an oxygen-deficient Atlantic open ocean eddy: future implications of ocean deoxygenation on primary production in the eastern tropical North Atlantic. Biogeosciences 12:7467–7482.
  • Weiland-Bräuer N, Neulinger SC, Pinnow N, Künzel S, Baines JF, Schmitz RA. 2015. Composition of bacterial communities associated with Aurelia aurita changes with compartment, life stage and population. Appl Environ Microbiol 81:6038-6052.
  • Heinsen F-A, Knecht H*, Neulinger SC*, Schmitz RA, Knecht C, Kühbacher T, Rosenstiel PC, Schreiber S, Friedrichs AK, Ott SJ. 2015. Dynamic changes of the luminal and mucosa-associated gut microbiota during and after antibiotic therapy with paromomycin. Gut Microbes 6:243-254.
  • Knecht H, Neulinger SC, Heinsen F-A, Knecht C, Schilhabel A, Schmitz RA, Zimmermann A, Martins dos Santos VAP, Ferrer M, Rosenstiel PC, Schreiber S, Friedrichs AK, Ott SJ. 2014. Effects of β-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea. PLoS ONE 9:e89417.
  • Langfeldt D, Neulinger SC, Stiesch M, Stumpp N, Bang C, Schmitz RA, Eberhard J. 2014. Health- and disease-associated species clusters in complex natural biofilms determine the innate immune response in oral epithelial cells during biofilm maturation. FEMS Microbiol Lett 360:137-143.
  • Langfeldt D, Neulinger SC, Heuer W, Staufenbiel I, Künzel S, Baines JF, Eberhard J, Schmitz RA. 2014. Composition of microbial oral biofilms during maturation in young healthy adults. PLoS ONE 9:e87449.
    Stratil SB, Neulinger SC, Knecht H, Friedrichs AK, Wahl M. 2014. Salinity affects compositional traits of epibacterial communities on the brown macroalga Fucus vesiculosus. FEMS Microbiol Ecol 88:272–279.
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Genetic Variant Analysis
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Draw conclusions from identified mutations in your sample

Studying mutations

Accurate identification of single-nucleotide polymorphisms (SNPs), insertions/deletions (Indels) and copy number variants (CNVs) is based on unambiguous mapping data. We deliver you with variant analysis service including high quality mapping from... Show more »

Draw conclusions from identified mutations in your sample

Studying mutations

Accurate identification of single-nucleotide polymorphisms (SNPs), insertions/deletions (Indels) and copy number variants (CNVs) is based on unambiguous mapping data. We deliver you with variant analysis service including high quality mapping from short and long read data and confidently summarizing the detection of Indels, point mutations or CNVs of your sample, reported in variant calling format (VCF). We annotate the findings against databases and further evaluate the pathogenicity of found genetic variants.

Send your data for mapping and variance analysis, we analyse:

  • Targeted (re)-sequencing data
  • Amplicon data
  • Whole-exome data
  • Whole-genome data
  • Whole-transcriptome data
  • Affymetrix SNP Array data

We offer you:

  • Quality check and preprocessing of FASTA/FASTQ files (454/Illumina)
  • Mapping of data against known references with subsequent mapping report
  • Variant calling using multiple callers
  • Summary of results in variant caller files (VCF)
  • Identification of homozygote/heterozygote variants
  • Variant annotation and classification to known references
  • Pathogenicity prediction of genetic variants
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Statistical Analysis
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We offer statistical consulting and analyses for your scientific project. It will significantly improve the quality of your publication, theses or presentation. Among other things, we can help you with:

  • Descriptive statistics
    • Tables
    • Diagrams
  • Exploratory data analysis

We offer statistical consulting and analyses for your scientific project. It will significantly improve the quality of your publication, theses or presentation. Among other things, we can help you with:

  • Descriptive statistics
    • Tables
    • Diagrams
  • Exploratory data analysis
    • Cluster analysis
    • Ordination in reduced space (PCA, PCoA, MDS)
  • Tests
    • parametric
    • non-parametric
  • Multivariate statistics
  • Generalized linear models
  • Linear and non-linear mixed effects models
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Viral Metagenomics
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Viruses are the most abundant biological entities on Earth. They have tremendous effects on ecosystems (as predators of prokaryotes), human health (as causative or indirect disease agents), and economy (affecting beneficial microbes in biotech processes).

Designated tools

Next-generation sequencing has raised virological... Show more »

Viruses are the most abundant biological entities on Earth. They have tremendous effects on ecosystems (as predators of prokaryotes), human health (as causative or indirect disease agents), and economy (affecting beneficial microbes in biotech processes).

Designated tools

Next-generation sequencing has raised virological studies to a new level. Viral metagenomics (viromics) reveals important information on the genetic diversity of a viral community without the need for isolating and cultivating viral species. At omics2view.consulting GbR, we apply designated analysis tools to

  • identify viral genes and contigs (possibly whole genomes) in environmental metagenomes;
  • clean viral metagenomes of contaminating host DNA;
  • retrieve available taxonomic information;
  • match viral metagenomes against host (meta)genomes;
  • discover distribution patterns in relation to environmental and clinical conditions.
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Fungal Community Analysis
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Fungi play a major role in many ecosystems, human health, and biotechnological processes (namely in food industry). Phylogenetic markers, namely Internal transcribed spacers (ITS), are commonly employed for characterization of fungal communities. Next-generation sequencing allows in-depth analysis of fungal community structure. We... Show more »

Fungi play a major role in many ecosystems, human health, and biotechnological processes (namely in food industry). Phylogenetic markers, namely Internal transcribed spacers (ITS), are commonly employed for characterization of fungal communities. Next-generation sequencing allows in-depth analysis of fungal community structure. We deliver comprehensive analyses of the structure of your fungal community in ecological and clinical samples, based on:

  • ITS1 or ITS2 regions
  • 18S rDNA (on request)

We use model-based multivariate statistics to determine the response of fungi to environmental factors. Moreover, we apply network analysis to unravel interactions of community members. This will help you to identify:

  • Shifts in fungal community structure
  • Habitat-specific indicator taxa
  • Association patterns
  • Environmental factors governing fungal distribution

Our experts will be happy to assist you with your project. For academic clients we procure sequencing of amplicon or genomic libraries on Illumina® MiSeq™ and NextSeq™ platforms.

Our experts will be happy to discuss your personal clinical microbiome project.

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Genome annotation
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Following assembly, we identify relevant genomic features of your microbial genome and provide them in formats ready for downstream analysis. Furthermore, we provide you with Circos plots of these genomic features and take care of data submission to Genbank or DDJB.

Following assembly, we identify relevant genomic features of your microbial genome and provide them in formats ready for downstream analysis. Furthermore, we provide you with Circos plots of these genomic features and take care of data submission to Genbank or DDJB.

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Whole genome assembly
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We assemble high-quality draft genomes of your microbes of interest, both de-novo(without reference) or reference-guided. We make use of paired-end as well as mate-pair libraries to get concise assemblies.

We assemble high-quality draft genomes of your microbes of interest, both de-novo(without reference) or reference-guided. We make use of paired-end as well as mate-pair libraries to get concise assemblies.

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Genomics Data Analysis
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The ability to sequence whole microbial genomes has revolutionized biology. Sequencing the genome of a microorganism is important to reveal its physiological potential or conduct comparative phylogenomic studies. We offer analysis of whole genome data resulting from individual microorganism or communities (Shotgun- Metagenomics, Shotgun Metatranscriptomics).

The ability to sequence whole microbial genomes has revolutionized biology. Sequencing the genome of a microorganism is important to reveal its physiological potential or conduct comparative phylogenomic studies. We offer analysis of whole genome data resulting from individual microorganism or communities (Shotgun- Metagenomics, Shotgun Metatranscriptomics).

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Microbiomics Data Analysis
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As experts for microbial profiling and functional analysis, we offer bioinformatic analysis services for microbiome data from:

  • Amplicon sequencing data (e.g., bacterial 16S rDNA/rRNA)
  • Shotgun metagenomics
  • Shotgun metatranscriptomics

Adhering to the current gold standards in microbiome data analysis, yet flexible to... Show more »

As experts for microbial profiling and functional analysis, we offer bioinformatic analysis services for microbiome data from:

  • Amplicon sequencing data (e.g., bacterial 16S rDNA/rRNA)
  • Shotgun metagenomics
  • Shotgun metatranscriptomics

Adhering to the current gold standards in microbiome data analysis, yet flexible to respond to your needs, we accompany your clinical or ecological microbiome projects from study design to publication. For academic clients we procure sequencing of amplicon or shotgun libraries on Illumina® MiSeq™ and NextSeq™ platforms.

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DNA Sequencing
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Data Services
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Clinical Research
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Computational Modeling
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Biology
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Sequencing Data Analysis
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Nucleic Acid Analysis
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Nucleic Acid Data Analysis
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Next Generation Sequencing (NGS)
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Microbiology, Virology, and Parasitology
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Metagenomics
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Clinical Molecular Diagnostics
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Clinical Laboratory Services
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DNA
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Biochemistry & Molecular Biology
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Nucleic Acid Services
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Genetic Marker Screening Services
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Microbiology Assays
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