Science Exchange

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Olympic Protein Technologies

Seattle, WA, US

Olympic Protein Technologies is a contract research organization focused on providing high quality protein science services for clients and partners. The quality of proteins are vital to the success of experiments that form the foundation of the discovery and development of therapeutics. Our staff has a wealth of collective experience in top-tier biotechnology companies successfully designing, producing and characterizing protein therapeutic candidates as well as critically important antigens and reagents. This experience includes solving problems associated with the expression/purification of challenging proteins. The aim of our team is to leverage this knowledge to provide the best experience and outcomes for our partners and clients by providing quality science delivered with full engagement and the highest standards, integrity, and data security.

We currently offer construct design, expression, protein... Show more »

Olympic Protein Technologies is a contract research organization focused on providing high quality protein science services for clients and partners. The quality of proteins are vital to the success of experiments that form the foundation of the discovery and development of therapeutics. Our staff has a wealth of collective experience in top-tier biotechnology companies successfully designing, producing and characterizing protein therapeutic candidates as well as critically important antigens and reagents. This experience includes solving problems associated with the expression/purification of challenging proteins. The aim of our team is to leverage this knowledge to provide the best experience and outcomes for our partners and clients by providing quality science delivered with full engagement and the highest standards, integrity, and data security.

We currently offer construct design, expression, protein production & characterization, biomolecular interaction analysis, and protein engineering services. We also leverage our network of protein science contacts to provide access to other types of analyses, such as advanced biophysical technologies, for your project. As we grow we will build on our existing capabilities while broadening our offerings to include other protein science services. We are located in Seattle Washington USA.

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Olympic Protein Technologies has not listed any services.

Surface Plasmon Resonance (SPR)
Price on request

Consultation, quantitative binding and kinetic constant determinations, high throughput screens, epitope binning, and assays for discovery work and regulatory submissions for a range of molecular types (small molecules and large molecules including ligands, receptors, mAbs, ADCs, bispecifics, and peptides)

*Affinity... Show more »

Consultation, quantitative binding and kinetic constant determinations, high throughput screens, epitope binning, and assays for discovery work and regulatory submissions for a range of molecular types (small molecules and large molecules including ligands, receptors, mAbs, ADCs, bispecifics, and peptides)

Affinity Determination by Biacore SPR
2-4 weeks
Determination of affinity and kinetic parameters for protein-protein and protein-ligand interactions

Custom Biacore Reagent Generation
Inquire
Custom reagents for SPR and assay studies

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Biacore
Molecular Cloning
Price on request

DNA Construction and Cloning
Encoding Native or Engineered Proteins and Antibodies

New Design
3 weeks
Design and synthesis of new DNA encoding protein of interest in an expression vector

Construction of Expression Vector
2 weeks
Subcloning of existing protein-encoding DNA into an expression vector

DNA Construction and Cloning
Encoding Native or Engineered Proteins and Antibodies

New Design
3 weeks
Design and synthesis of new DNA encoding protein of interest in an expression vector

Construction of Expression Vector
2 weeks
Subcloning of existing protein-encoding DNA into an expression vector

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Cloning
Hybridoma sequencing
Price on request

Hybridoma Antibody Variable Domain Sequencing
2-3 weeks
Determine nucleotide sequences of variable domains from antibody heavy and light chains derived from hybridomas

Hybridoma Antibody Variable Domain Sequencing
2-3 weeks
Determine nucleotide sequences of variable domains from antibody heavy and light chains derived from hybridomas

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Mouse
Transient Protein Expression
Price on request

Test for Transient Expression in Mammalian Cells
2 weeks
Small scale test for expression of new construct in mammalian cell system

Scale Up Transient Expression in Mammalian Cells
2 weeks
Constructs that pass the expression test are scaled up in ranges spanning culture volumes of 100 ml to 8 liters.

Test for Transient Expression in Mammalian Cells
2 weeks
Small scale test for expression of new construct in mammalian cell system

Scale Up Transient Expression in Mammalian Cells
2 weeks
Constructs that pass the expression test are scaled up in ranges spanning culture volumes of 100 ml to 8 liters.

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mammalian
HEK293
Bacterial Protein Expression
Price on request

Test for Expression in Bacterial Cells
1 week
Small scale test for expression of new construct in bacterial cell system

Scale Up Expression in Bacterial Cells
1 week
Constructs that pass the expression test are scaled up in ranges spanning culture volumes of 100 ml to several liters

Test for Expression in Bacterial Cells
1 week
Small scale test for expression of new construct in bacterial cell system

Scale Up Expression in Bacterial Cells
1 week
Constructs that pass the expression test are scaled up in ranges spanning culture volumes of 100 ml to several liters

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Escherichia coli
Protein Purification
Price on request

Purification from Mammalian Cells
2 Weeks
Purification and characterization of protein expressed from mammalian cells

Purification from Bacterial Cells
2 weeks
Purification and characterization of protein expressed from bacterial cells

Antibody Panels
Inquire
Expression and purification of panels of antibodies -... Show more »

Purification from Mammalian Cells
2 Weeks
Purification and characterization of protein expressed from mammalian cells

Purification from Bacterial Cells
2 weeks
Purification and characterization of protein expressed from bacterial cells

Antibody Panels
Inquire
Expression and purification of panels of antibodies - various scales available

Protein Refolding
3 weeks
Refolding of proteins from E coli inclusion bodies

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AKTA FPLC
Antibody and Protein labeling
Price on request

Inquire
Modifications include biotinylations and the conjugation of fluorescent dyes and other tags

Inquire
Modifications include biotinylations and the conjugation of fluorescent dyes and other tags

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Fluorescent labeling
Biotinylation
Assay Development
Price on request

Various formats available

Various formats available

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ELISA
Biacore
Protein Engineering
Price on request

Structure-Based Analysis
Inquire
Analysis incorporating structural and bioinformatic aspects for translating design goal elements to a list of testable protein variants

Single or Multiple Point Mutants and Screening
Inquire
Focused exploration of protein variants

Library Design and Screening
Inquire
Broad exploration of protein variants

Structure-Based Analysis
Inquire
Analysis incorporating structural and bioinformatic aspects for translating design goal elements to a list of testable protein variants

Single or Multiple Point Mutants and Screening
Inquire
Focused exploration of protein variants

Library Design and Screening
Inquire
Broad exploration of protein variants

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