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NOVOGENE (UK) COMPANY LTD

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Cambridge, GB

About NOVOGENE (UK) COMPANY LTD

Novogene is a leading provider of genomic services and solutions with cutting edge NGS and bioinformatics expertise, and thelargest sequencing capacity in the world. Novogene utilizes scientific excellence, a commitment to customer service and unsurpassed data quality to help our clients realize their research... Show more »

Novogene is a leading provider of genomic services and solutions with cutting edge NGS and bioinformatics expertise, and thelargest sequencing capacity in the world. Novogene utilizes scientific excellence, a commitment to customer service and unsurpassed data quality to help our clients realize their research goals. The company has become a world-leader in NGS services, with 1,800 employees and multiple locations across the globe. Novogene’s depth of experience has resulted in the ownership of 49 NGS-related patents, as well as the publishing of over 1850 customer research papers, often in well-respected publications such as Nature and Science.

Company founder, Dr. Ruiqiang Li , is widely recognized as one of the world’s leading experts in genomics and bioinformatics, owning 12 patents and authoring over 90 peer-reviewed publications that have been cited >15,000 times. Best known for developing the software SOAP ( Short Oligonucleotide Analysis Package) for ultra-fast sequence mapping, variation detection, and de novo genome assembly, Dr. Li has focused Novogene’s services on performing sequencing AND Advisory informatics to fully empower and enable our customers to move forward rapidly and effectively in their scientific Endeavors.

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Our Services (11)


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Whole Genome Sequencing

Price on request

Human whole genome sequencing enables researchers to catalog genetic constitution of individuals and capture all variants present in a single assay. It is utilized to study cancer and a variety of diseases, as well as human population evolution studies and pharmacogenomics. Equipped with powerful Illumina HiSeq X and NovaSeq... Show more »

Human whole genome sequencing enables researchers to catalog genetic constitution of individuals and capture all variants present in a single assay. It is utilized to study cancer and a variety of diseases, as well as human population evolution studies and pharmacogenomics. Equipped with powerful Illumina HiSeq X and NovaSeq 6000 systems, Novogene is capable of sequencing up to 280,000 human genomes per year at the lowest cost per genome. Being one of the first few companies to adopt HiSeq X Ten since early 2014, we have extensive experience providing whole genome sequencing services, having successfully sequenced hundreds of thousands of genomes with high quality results. With the world’s largest sequencing capacity, extensive experience in whole genome sequencing, and advanced bioinformatics capabilities, Novogene is able to expertly meet customer needs for delivering large project results with quick turnaround and the highest quality results.

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Whole Exome Sequencing (WES)

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Exome sequencing provides a cost-effective alternative to whole genome sequencing, as it targets only the protein coding region of the human genome responsible for a majority of known disease-related variants. Whether you are conducting studies in rare mendelian disorders, complex disease, cancer research, or human population... Show more »

Exome sequencing provides a cost-effective alternative to whole genome sequencing, as it targets only the protein coding region of the human genome responsible for a majority of known disease-related variants. Whether you are conducting studies in rare mendelian disorders, complex disease, cancer research, or human population studies, Novogene’s comprehensive human whole exome sequencing service provides a high-quality, affordable, and convenient solution. Novogene’s bioinformatics analysis includes data QC, mapping with reference genome, SNP/InDel, somatic SNP/InDel calling, statistics, and annotation. Novogene utilizes internationally recognized softwares in bioinformatics analysis, e.g. BWA, SAMtools, GATK, etc. In particular, Novogene's bioinformatics pipeline includes annotation with the exome aggregation consortium (ExAC). ExAC dataset spans 60,706 unrelated individuals sequenced as part of various disease-specific and population genetic studies. This population scale database greatly facilitates research of disease pathogenesis.

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De Novo Genome Sequencing

Price on request

Using de novo sequencing to obtain the genomic information of microbes provides a fresh start for exploring the genetic structure and functions, studying the evolutionary origin of microbial populations, as well as developing potential applications of these abundant microbes in medicine, disease, agriculture, and... Show more »

Using de novo sequencing to obtain the genomic information of microbes provides a fresh start for exploring the genetic structure and functions, studying the evolutionary origin of microbial populations, as well as developing potential applications of these abundant microbes in medicine, disease, agriculture, and environment. Novogene is at the forefront of de novo sequencing as it becomes more rapid and affordable. Novogene’s founder, Dr. Ruiqiang Li, is a leading genomics expert and a primary developer of the SOAPdenovo software package for genome assembly. Dr. Li and the Novogene team have contributed to many important publications on novel genome sequences, and we can provide you with the high level of expertise required for your specific project. For the microbial genome, Novogene offers de novo sequencing service using both PacBio and Illumina platforms. We provide multifaceted sequencing services including genome survey, frame map, complete map, and fine map tailored to different research needs. For each project, our scientists will design the best sequencing strategy utilizing an optimal combination of short reads and long-range sequencing information to achieve the most comprehensive de novo assembly results for your genome of interest.

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Amplicon Sequencing

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Amplicon sequencing  is frequently used to identify and differentiate microbial species. Short (<500 bp) hypervariable regions of conserved genes or intergenic regions are amplified by PCR and analyzed using NGS technology, and the resulting sequences are compared against microbial databases.For bacteria and... Show more »

Amplicon sequencing  is frequently used to identify and differentiate microbial species. Short (<500 bp) hypervariable regions of conserved genes or intergenic regions are amplified by PCR and analyzed using NGS technology, and the resulting sequences are compared against microbial databases.For bacteria and archaea, the 16S rRNA gene is the most common target for amplicon sequencing. For fungi, three targets are generally used: the 18S rRNA gene and two internal transcribed spacers (ITS) located between rRNA genes. These regions are usually sufficiently divergent to separate even highly related species, and can sometimes differentiate subspecies.At Novogene, we have sequenced over 170,000 microbial samples for our customers. Our standard bioinformatics analyses include alpha-diversity analysis, OTU analysis, species annotation, beta-diversity analysis, and multi-variate statistical analysis. Applications range from identifying a single species in pure culture to characterizing the microbiota of animals or plants, to comparing species diversity and population structure in various environmental sources or geographic regions. Our specialists can advise you on the appropriate analyses for your project.

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Metagenomics

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In metagenomics, genomes from environmental samples are analyzed without the prior isolation and cultivation of individual species; therefore, it is a powerful technique for studying microbial communities in their natural habitat, with a broad range of applications. At Novogene, our customers can rely on our expertise in NGS to... Show more »

In metagenomics, genomes from environmental samples are analyzed without the prior isolation and cultivation of individual species; therefore, it is a powerful technique for studying microbial communities in their natural habitat, with a broad range of applications. At Novogene, our customers can rely on our expertise in NGS to help them explore the rich genetic repertoire of microbial communities, while also benefiting from our bioinformatics expertise to help identify the species, genes, and pathways represented in their samples. Novogene provides metagenomic sequencing service with Illumina HiSeq platform and assembly-first strategy, and our bioinformatics analyses provide gene predictions, function annotations, and taxonomic annotations. Our standard analysis package includes mPATH, heatmaps, PCA, cluster analysis, and other programs, generating high-quality, publication-ready data.

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RNA Sequencing

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ChIP-Seq

Chromatin Immunoprecipitation Sequencing
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mRNA Sequencing

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Circular RNA Sequencing

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Epigenetic Studies

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Transcriptome Sequencing and Profiling

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