1386200410850 b2971481cd01f53638d43b3fb2d4b66e

Noble Life Sciences

ic 8.6/10 Overall Rating No Reviews Yet
ic 14 Orders Completed
Gaithersburg, Maryland, US

About Noble Life Sciences

Founded: 2010 Type: Privately Held Size: 11-50 employees

Noble Life Sciences is a woman owned preclinical contract research organization offering GLP and non-GLP services, in both large and small animals, for the development of drugs, vaccines, and medical devices. Preclinical development services include PK and PD studies; biodistribution studies; immunization and... Show more »

Noble Life Sciences is a woman owned preclinical contract research organization offering GLP and non-GLP services, in both large and small animals, for the development of drugs, vaccines, and medical devices. Preclinical development services include PK and PD studies; biodistribution studies; immunization and immunogenicity testing; early safety assessments; reproductive and developmental toxicity testing; surgical services; medical device protocol development and testing; analytical and imaging services; and preclinical formulation development. Our services also include the derivation and maintenance of animal breeding colonies, animal housing and husbandry, the development of disease and animal models, and the production of custom antibodies and are backed by AAALAC accreditation, OLAW assurance, a USDA license and over 50 years of experience.

Facility certifications:
- AAALAC Accredited
- OLAW Assurance
- USDA Licensed
- FDA Inspected
-Woman owned small business

Standard shipment requests:
Contact Shipping Coordinator prior to any arranged scheduling

Show less

Certifications & Qualifications

AAALAC BSL-2 FDA Inspected GLP IACUC OLAW USDA

Diversity Certificates

Woman owned small business

Our Services (47)


ic

Medical Device Testing

Price on request

Medical Device testing services in Orthopedics, Spinal Fusion, Cardiovascular, Trauma, Wound Healing, Imaging

Medical Device testing services in Orthopedics, Spinal Fusion, Cardiovascular, Trauma, Wound Healing, Imaging

Show less

ic

In vivo Drug Efficacy Testing

Price on request

Broad range of rodent in vivo efficacy PK/PD models

Broad range of rodent in vivo efficacy PK/PD models

Show less
Rabbit Ferret Mouse Rat

ic

Animal Immunization for Antibody Production

Price on request
Request a quote for more information about this service.
Hamster Rabbit Guinea pig Ferret Sheep Goat Mouse Rat Show 8 more tags Show less

ic

Polyclonal Antibody Production

Price on request

Standard and fast protocols, multiple adjuvant, antigen and immunization options; sample processing, purification and ELISA

Standard and fast protocols, multiple adjuvant, antigen and immunization options; sample processing, purification and ELISA

Show less

ic

Animal Plasma and Serum

Price on request
Request a quote for more information about this service.

ic

Animal Tissue Procurement

Price on request

Animal blood, serum and tissue from various species; aseptic collection

Animal blood, serum and tissue from various species; aseptic collection

Show less

ic

In vivo Immunogenicity Assays

Price on request
Request a quote for more information about this service.
Hamster Rabbit Guinea pig Ferret Sheep Goat Mouse Pig Rat Minipig Show 10 more tags Show less

ic

Drug Release Studies/In Vitro Release Testing (IVRT)

Price on request
Request a quote for more information about this service.

ic

Cell Line Derived Xenograft (CDX) Models

Cell Line Derived Xenograft Models
Price on request

Xenograft tumors are usually established via subcutaneous inoculation of a predetermined number of tumor cells into the flank of nude mice. Xenograft models are commonly used to determine ideal drug dosing, treatment schedules, and routes of drug administration that maximize anti-tumor efficacy and therapeutic window.

Pricing:... Show more »

Xenograft tumors are usually established via subcutaneous inoculation of a predetermined number of tumor cells into the flank of nude mice. Xenograft models are commonly used to determine ideal drug dosing, treatment schedules, and routes of drug administration that maximize anti-tumor efficacy and therapeutic window.

Pricing: per animal
Average turnaround time: 30 days

METHODOLOGY:
- Human cancer cells are injected into 6-week old female NU NU mice.
- Tumor size measurements are initiated 8 days post inoculation and monitored two times per week.
- Tumor measurements are evaluated using calipers; tumor size is calculated as: MIN (L:W)2x MAX(L:W)/2.

OPTIONS:
- Animals: Mice or Rats
- Cell Line: Client-specified strain
- Route of Drug Administration: Intraperitoneal, intramuscular, intratumoral, intravenous, subcutaneous
- Reference Substance & Control: Client-specified reference drug; vehicle
- Length/Endpoint: Death or protocol-specified endpoint
- Assays & Measurements: Tumor growth rate, tumor growth delay, tumor growth inhibition, PK/PD analyses, molecular analyses

(See storefront attachment for more info.)

Show less
Mouse

ic

Monoclonal Antibody (mAb) Production

Price on request

Mouse, Guinea Pig, Ferret, Rat, Rabbit, Sheep and Goat
Standard or FAST Protocol

Mouse, Guinea Pig, Ferret, Rat, Rabbit, Sheep and Goat
Standard or FAST Protocol

Show less
Hamster Rabbit Guinea pig Ferret Sheep Goat Mouse Rat Show 8 more tags Show less

ic

In vivo Toxicity Testing

Price on request

Immunogenicity and repeat dose toxicity, biosdistribution, reproductive and developmental toxicity testing as well as product release testing

GLP

Immunogenicity and repeat dose toxicity, biosdistribution, reproductive and developmental toxicity testing as well as product release testing

GLP

Show less
Hamster Rabbit Guinea pig Ferret Sheep Mouse Pig Rat Show 8 more tags Show less

ic

Bacterial Infection Animal Models

Price on request

Infectious disease models

Complicated skin and soft tissue infections are frequently encountered in clinical practice and are a significant cause of morbidity and mortality in hospitalized patients. The neutropenic mouse thigh model of infection has been used extensively to test and benchmark antimicrobial drugs leading to a... Show more »

Infectious disease models

Complicated skin and soft tissue infections are frequently encountered in clinical practice and are a significant cause of morbidity and mortality in hospitalized patients. The neutropenic mouse thigh model of infection has been used extensively to test and benchmark antimicrobial drugs leading to a significant impact on our current knowledge of antimicrobial pharmacology. This model allows the quantitative comparison of different agents and different dosing regimes and the determination of the time-course of antimicrobial activity under conditions optimal for efficacy, i.e., neutropenia. Because the pharmacology of antimicrobial agents is affected by the presence of neutrophils, animals are commonly rendered neutropenic with cytotoxic agents like cyclophosphamide, the most frequently used immunosuppressive agent in animal infection models.

Turnaround time: Average 30 days

Show less

ic

IBS/IBD Animal Models

Irritable Bowel Syndrome/Disease Animal Models
Price on request
Request a quote for more information about this service.

ic

Assay Development

Price on request
Request a quote for more information about this service.

ic

Infusion Pump Implantation in Animals

Price on request

Implantable continuous infusion osmotic pumps have several applications in preclinical drug development. The pumps enable continuous, controlled dosing and thereby allow the achievement of steady state conditions and accurate compound delivery.

Turnaround time: Average 45 days

Implantable continuous infusion osmotic pumps have several applications in preclinical drug development. The pumps enable continuous, controlled dosing and thereby allow the achievement of steady state conditions and accurate compound delivery.

Turnaround time: Average 45 days

Show less

ic

Influenza Animal Models

Price on request

Vaccine Models including RSV and Influenza
Other Mouse Models for In Vivo Study Challenges
Expert Cotton Rat Model

Turnaround time: Average 30 days

Vaccine Models including RSV and Influenza
Other Mouse Models for In Vivo Study Challenges
Expert Cotton Rat Model

Turnaround time: Average 30 days

Show less
Mouse Rat Influenza Respiratory syncytial virus (RSV)

ic

RSV Animal Models

Respiratory Syncytial Virus Animal Models
Price on request

Vaccine Models including RSV and Influenza
Other Mouse Models for In Vivo Study Challenges
Expert Cotton Rat Model

Turnaround time: Average 30 days

Vaccine Models including RSV and Influenza
Other Mouse Models for In Vivo Study Challenges
Expert Cotton Rat Model

Turnaround time: Average 30 days

Show less

ic

Rodent Breeding

Price on request

Services included customized contract breeding of your genetically altered mouse and rat research models, genotyping, and delivery of the exact quantity, sex, age and genotype of study animal groups to free your vivarium capacity. Client receives rapid feedback, turnaround time, and regular updates on colony development, customized to meet their immediate needs

Services included customized contract breeding of your genetically altered mouse and rat research models, genotyping, and delivery of the exact quantity, sex, age and genotype of study animal groups to free your vivarium capacity. Client receives rapid feedback, turnaround time, and regular updates on colony development, customized to meet their immediate needs

Show less

ic

Human Tumor Xenograft Models

Price on request

In vivo xenograft studies

Mouse models of cancer have consistently been used to determine the in vivo activity of new anti-cancer therapeutics prior to clinical development and testing in humans.

The most common models are xenografts of human tumors and cell lines grown subcutaneously in
immunodeficient mice such as athymic... Show more »

In vivo xenograft studies

Mouse models of cancer have consistently been used to determine the in vivo activity of new anti-cancer therapeutics prior to clinical development and testing in humans.

The most common models are xenografts of human tumors and cell lines grown subcutaneously in
immunodeficient mice such as athymic (nude) or severe combined immune deficient (SCID) mice. These mouse strains exhibit very high take rates for xenografts, making them ideal hosts for in vivo propagation of human tumor cells.

Xenograft tumors are usually established via subcutaneous inoculation of a predetermined number of tumor cells into the flank of nude mice. Xenograft models are commonly used to determine ideal drug dosing, treatment schedules, and routes of drug administration that maximize anti-tumor efficacy and therapeutic window.

Pricing: per animal
Average turnaround time: 30 days

METHODOLOGY:
- Human cancer cells are injected into 6-week old female NU NU mice.
- Tumor size measurements are initiated 8 days post inoculation and monitored two times per week.
- Tumor measurements are evaluated using calipers; tumor size is calculated as: MIN (L:W)2x MAX(L:W)/2.

OPTIONS:
- Animals: Mice or Rats
- Cell Line: Client-specified strain
- Route of Drug Administration: Intraperitoneal, intramuscular, intratumoral, intravenous, subcutaneous
- Reference Substance & Control: Client-specified reference drug; vehicle
- Length/Endpoint: Death or protocol-specified endpoint
- Assays & Measurements: Tumor growth rate, tumor growth delay, tumor growth inhibition, PK/PD analyses, molecular analyses

(See storefront attachment for more info.)

Show less

ic

In vitro Diagnostic Development

Price on request
Request a quote for more information about this service.

ic

Medical Device Development

Price on request
Request a quote for more information about this service.

ic

Gastroenterology Animal Models

Price on request
Request a quote for more information about this service.

ic

Animal Model in vivo Analyses

Price on request
Request a quote for more information about this service.

ic

Safety Pharmacology

Price on request
Request a quote for more information about this service.

ic

Biochemistry & Molecular Biology

Price on request
Request a quote for more information about this service.

ic

Toxicology

Price on request
Request a quote for more information about this service.
Rabbit Guinea pig Ferret Sheep Mouse Pig Rat Show 7 more tags Show less

ic

Oncology Animal Models

Price on request
Request a quote for more information about this service.

ic

Infectious Disease Animal Models

Price on request
Request a quote for more information about this service.

ic

Cells and Tissues

Price on request
Request a quote for more information about this service.

ic

Animal Models and Studies

Price on request
Request a quote for more information about this service.

ic

Formulation Services

Price on request

Formulation & Manufacturing Services

Formulation & Manufacturing Services

Show less

ic

Biology

Price on request
Request a quote for more information about this service.

ic

Therapeutic Monoclonal Antibody (mAb) Development

Price on request
Request a quote for more information about this service.

ic

Animal Model Housing and Maintenance

Price on request
Request a quote for more information about this service.

ic

Project Management

Price on request
Request a quote for more information about this service.

ic

Animal Biospecimens

Price on request
Request a quote for more information about this service.
Rabbit Guinea pig Ferret Sheep Mouse Pig Rat Show 7 more tags Show less

ic

Animal Models of Disease

Price on request
Request a quote for more information about this service.

ic

Animal Physiology Analyses

Price on request
Request a quote for more information about this service.

ic

Medical Devices & Diagnostics

Price on request
Request a quote for more information about this service.

ic

Pharmacology & Toxicology

Price on request
Request a quote for more information about this service.

ic

Xenograft Models

Price on request
Request a quote for more information about this service.

ic

Antibody Services

Price on request
Request a quote for more information about this service.

ic

Biospecimens

Price on request
Request a quote for more information about this service.

ic

Animal Surgery

Price on request
Request a quote for more information about this service.

ic

Animal Husbandry

Price on request
Request a quote for more information about this service.

ic

Pharmacology

Price on request

Pharmacology Services

Pharmacology Services

Show less

ic

Drug Discovery & Development

Price on request

Drug Discovery & Development Services

Drug Discovery & Development Services

Show less

Not finding what you're looking for?

Get info on this provider's capabilities without requesting a quote.
Missing Avatar

Srujana Cherukuri

Chief Executive Officer
FileType/PDF Created with Sketch.

Cotton Rat Model of RSV Infection 01-30-14RDC.pdf

FileType/PDF Created with Sketch.

Human Xenograft Models 03-25-14.pdf

FileType/PDF Created with Sketch.

MRSA Sepsis Model 05-14 dc.pdf

FileType/Other Created with Sketch.

Noble Capabilities Presentation March 9 2015.ppt

Noble Life Sciences has not received any reviews.

Noble Life Sciences has not received any endorsements.