B4esru4htqcn8yyahxwi screen shot 2017 01 25 at 4.11.41 pm

Nexomics Biosciences

Nexomics proudly offers gene-to-structure services to the biopharmaceutical and biological research community. With a strong focus on discovery and analytical R&D services, our core capabilities include target selection and construct design using bioinformatics tools, cloning of genes into protein production vectors, recombinant protein expression, laboratory-scale fermentation, protein purification, crystallization screening, NMR structural studies, X-ray crystallographic structural studies, and functional assay development.

Selected Publications

Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN, Carter J, Dalby AB, Eaton BE, Fitzwater T, Flather D, Forbes A, Foreman T, Fowler C, Gawande B, Goss M, Gunn M, Gupta S, Halladay D, Heil J, Heilig J, Hicke B, Husar G, Janjic N, Jarvis T, Jennings S, Katilius E, Keeney TR, Kim N, Koch TH, Kraemer S, Kroiss L, Le N, Levine D, Lindsey W, Lollo B, Mayfield W, Mehan... Show more »

Nexomics proudly offers gene-to-structure services to the biopharmaceutical and biological research community. With a strong focus on discovery and analytical R&D services, our core capabilities include target selection and construct design using bioinformatics tools, cloning of genes into protein production vectors, recombinant protein expression, laboratory-scale fermentation, protein purification, crystallization screening, NMR structural studies, X-ray crystallographic structural studies, and functional assay development.

Selected Publications

Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN, Carter J, Dalby AB, Eaton BE, Fitzwater T, Flather D, Forbes A, Foreman T, Fowler C, Gawande B, Goss M, Gunn M, Gupta S, Halladay D, Heil J, Heilig J, Hicke B, Husar G, Janjic N, Jarvis T, Jennings S, Katilius E, Keeney TR, Kim N, Koch TH, Kraemer S, Kroiss L, Le N, Levine D, Lindsey W, Lollo B, Mayfield W, Mehan M, Mehler R, Nelson SK, Nelson M, Nieuwlandt D, Nikrad M, Ochsner U, Ostroff RM, Otis M, Parker T, Pietrasiewicz S, Resnicow DI, Rohloff J, Sanders G, Sattin S, Schneider D, Singer B, Stanton M, Sterkel A, Stewart A, Stratford S, Vaught JD, Vrkljan M, Walker JJ, Watrobka M, Waugh S, Weiss A, Wilcox SK, Wolfson A, Wolk SK, Zhang C, Zichi D. Aptamer-based multiplexed proteomic technology for biomarker discovery. PLoS One. 2010 Dec 7;5(12):e15004. doi: 10.1371/journal.pone.0015004.

« Show less

Nexomics Biosciences has not listed any services.

Ask A Question Find what you're looking for? If not, you can ask this lab a question:
Protein Expression
Price on request

Nexomics offers protein expression services at various scales (small, midi, and large scales, up to 30 L Bioreactor scale).

We support a wide range of expression systems and media types (LB / TB with Animal-Free Soytone, MJ9).

We have unique expertise in preparing stable isotope-enriched media (15N, 15N13C, 15N13C2D-ILV, 19F) for protein specific isotope labeling.

Nexomics offers protein expression services at various scales (small, midi, and large scales, up to 30 L Bioreactor scale).

We support a wide range of expression systems and media types (LB / TB with Animal-Free Soytone, MJ9).

We have unique expertise in preparing stable isotope-enriched media (15N, 15N13C, 15N13C2D-ILV, 19F) for protein specific isotope labeling.

« Show less
Yeast
E. coli
Bacteria
cell paste
cell lysate
SARTORIUS Braun Biotech Biostat 30 L Fermenter
New Brunswick Scientific Incubator Shakers
Fed-Batch Fermentation
Fermentation
lyophilized cell
bacterial based recombinant protein production
Protein Purification
Price on request

Nexomics uses ÄKTA Protein Purification Systems to obtain the highest purity protein samples.

Large scale protein purification (up to grams range) using affinity or ion exchange chromatography (up to 500 ml column volume).

Molecular weight is confirmed by MALDI-TOF Mass Spectrometry.

Nexomics uses ÄKTA Protein Purification Systems to obtain the highest purity protein samples.

Large scale protein purification (up to grams range) using affinity or ion exchange chromatography (up to 500 ml column volume).

Molecular weight is confirmed by MALDI-TOF Mass Spectrometry.

« Show less
GE Unicorn
gram
microgram
Biology
Drug discovery
Affinity chromotography
Biologics
Human protein microarray
protein
Antibody Production
His-tag
Chromatographic tests
ÄKTA Protein Purification Systems
solution
powder
non-tag
antibody
antigen
bacterial based recombinant protein production
NMR
Nuclear magnetic resonance spectroscopy
Price on request

Nexomics has deep experience with NMR structural biology techniques. We offer a full range of services from data collection, data processing, data analysis and structure determination.

Backbone Resonance Assignments
Sidechain Resonance Assignments
Protein-Protein and Protein-Ligand Interactions
Protein Structure... Show more »

Nexomics has deep experience with NMR structural biology techniques. We offer a full range of services from data collection, data processing, data analysis and structure determination.

Backbone Resonance Assignments
Sidechain Resonance Assignments
Protein-Protein and Protein-Ligand Interactions
Protein Structure Determination
Small Molecule Screening
Dynamics
19F NMR
Structure mapping by NMR
Quality control and Quantitative analysis

« Show less
NMR
800 MHz Bruker
600 MHz (1.7 mm cryoprobe) Bruker, with sample changer
600 MHz (cryoprobe) Bruker
500 MHz Varian
19F and 1H, 2H, 13C, 15N-TR NMR Probes
Backbone assignments
Side-chain assignment
Protein-Protein, Protein-Nucleic Acid complex analysis
Dynamics, disorder, stability
Biosimilarity analysis
X-ray Crystallography
Price on request

Nexomics has extensive experience solving protein crystal structures, including protein-protein, and protein-nucleic acid complexes, using X-ray crystallography.

Crystallization Screening
Crystallization Optimization
Diffraction Data Collection
Protein Structure Determination

Nexomics has extensive experience solving protein crystal structures, including protein-protein, and protein-nucleic acid complexes, using X-ray crystallography.

Crystallization Screening
Crystallization Optimization
Diffraction Data Collection
Protein Structure Determination

« Show less
HTP screening (1536 conditions)
Standard kit-based screening
Crystal Optimization
X-ray crystallography
Data Collection
Homology Modeling
Price on request

Homology models are useful for pathway modeling, predictive protein-protein / protein-ligand interactive simulations and in general as a guide in the protein structure determination process. Nexomics Biosciences offers homology modeling using our proprietary modeling and structure validation software.

Homology models are useful for pathway modeling, predictive protein-protein / protein-ligand interactive simulations and in general as a guide in the protein structure determination process. Nexomics Biosciences offers homology modeling using our proprietary modeling and structure validation software.

« Show less
Bioinformatics
protein modelling
structural bioinformatics
Protein Biophysical Characterization
Price on request

Nexomics utilizes a number of experimental biophysical techniques to ensure quality control as well as for further understanding of the biological system under study.

Nexomics utilizes a number of experimental biophysical techniques to ensure quality control as well as for further understanding of the biological system under study.

« Show less
Primer Design
Price on request

Designing the correct primer sequence can have a large impact on the success of a PCR reaction.

Through our automated proprietary primer design software we can design and deliver the optimal set of primers to ensure success.

Designing the correct primer sequence can have a large impact on the success of a PCR reaction.

Through our automated proprietary primer design software we can design and deliver the optimal set of primers to ensure success.

« Show less
Gene Synthesis
Price on request

Gene Synthesis is a powerful new technology for delivering difficult-to-isolate genes.

Gene synthesis is particularly useful when applying domain parsing techniques, mutagenesis techniques, or when working with difficult-to-isolate eukaryotic cDNA pools.

Gene Synthesis is a powerful new technology for delivering difficult-to-isolate genes.

Gene synthesis is particularly useful when applying domain parsing techniques, mutagenesis techniques, or when working with difficult-to-isolate eukaryotic cDNA pools.

« Show less
MALDI TOF MS
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
Price on request

MALDI-TOF mass spectroscopy is used as a quality control check for all protein production projects. The technology can also be used to measure regions of disorder within a protein.

MALDI-TOF mass spectroscopy is used as a quality control check for all protein production projects. The technology can also be used to measure regions of disorder within a protein.

« Show less
MALDI-TOF
MALDI-TOF Mass Spec
Mass Spectrometry
Light Scattering Services
Price on request

Light scattering data are useful for confirming oligomerization states of protein (e.g., monomer, dimer, etc.). And for determining shape-independent molecular weights.

Lights scattering studies are also valuable for construct optimization to enhance crystallization propensities of proteins.

Light scattering data are useful for confirming oligomerization states of protein (e.g., monomer, dimer, etc.). And for determining shape-independent molecular weights.

Lights scattering studies are also valuable for construct optimization to enhance crystallization propensities of proteins.

« Show less
Biolayer Interferometry
Price on request

BLI optical analytical technique to evaluate and characterize bimolecular interactions.
It can be used in assay development and to determine protein interaction affinities.

BLI optical analytical technique to evaluate and characterize bimolecular interactions.
It can be used in assay development and to determine protein interaction affinities.

« Show less
Static Light Scattering
Price on request
Request a quote for more information about this service.
Radiolabeling
Price on request

Protein specific stable isotope labeling Services

Nexomics has extensive experience incorporating stable isotopes (e.g. 15N, 13C, 2H, 19F) into native protein to facilitate NMR and mass spectrometry studies.

Protein specific stable isotope labeling Services

Nexomics has extensive experience incorporating stable isotopes (e.g. 15N, 13C, 2H, 19F) into native protein to facilitate NMR and mass spectrometry studies.

« Show less
Protein Services
Price on request
Request a quote for more information about this service.
Imaging & Spectroscopy
Price on request
Request a quote for more information about this service.
Structural Biology
Price on request
Request a quote for more information about this service.
PCR
Price on request
Request a quote for more information about this service.
Protein Purification and Quantification
Price on request
Request a quote for more information about this service.
MALDI Mass Spectrometry Methods
Price on request
Request a quote for more information about this service.
Nucleic Acid Services
Price on request
Request a quote for more information about this service.
DNA Services
Price on request
Request a quote for more information about this service.
Interferometry
Price on request
Request a quote for more information about this service.
Biology
Price on request
Request a quote for more information about this service.
DNA Synthesis and Probe Development
Price on request
Request a quote for more information about this service.
Biochemistry & Molecular Biology
Price on request
Request a quote for more information about this service.
Scattering Techniques
Price on request
Request a quote for more information about this service.
Spectroscopy
Price on request
Request a quote for more information about this service.
Chemistry and Materials
Price on request
Request a quote for more information about this service.
Computational Modeling
Price on request
Request a quote for more information about this service.
Protein Characterization Services
Price on request
Request a quote for more information about this service.
Mass Spectrometry
Price on request
Request a quote for more information about this service.
FPLC
Fast Performance liquid chromatography
Price on request
Request a quote for more information about this service.
Analytical Chemistry Services
Price on request

Analytical Chemistry Services

Analytical Chemistry Services

« Show less
Purification Services
Price on request

Purification Services

Purification Services

« Show less
Chromatography
Price on request

Chromatography Services

Chromatography Services

« Show less
Liquid Chromatography
Price on request

Liquid Chromatography Services

Liquid Chromatography Services

« Show less
2018-07-18 00:59:01 +0800

Net Promoter Score of 10 received for Protein Services.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-06-04 23:50:16 +0800

Net Promoter Score of 10 received for Protein Purification.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-03-24 01:38:18 +0800

Net Promoter Score of 10 received for Protein Expression.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2018-02-02 13:04:14 +0800

Net Promoter Score of 7 received for Protein Expression.

Additional Ratings: satisfaction with deliverable: 7, satisfaction with timeliness: 10.
2017-12-20 11:13:16 +0800

Net Promoter Score of 8 received for Protein Expression.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 8.
2017-12-13 06:26:59 +0800

Net Promoter Score of 8 received for Protein Purification.

Additional Ratings: satisfaction with deliverable: 7, satisfaction with timeliness: 8.

Be the first to endorse Nexomics Biosciences

Endorse this lab