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Newomics Inc.

Emeryville, California, US

Newomics Inc., a biotechnology company in the San Francisco Bay Area, commercializes innovative (New) and integrative (Omics) platforms and solutions for personalized healthcare. Our proprietary technology is based on silicon-microfluidic-chip for liquid chromatography-mass spectrometry (LC-MS), and offers unprecedented robustness, sensitivity, specificity, and throughput for analyzing molecules from minute amounts of biospecimens such as blood and urine. Our core technologies are built upon the multinozzle emitter array (MEA) technology, invented from the Lawrence Berkeley National Laboratory (Berkeley Lab), which has won the 2012 R&D 100 award. Our first product Newomics® M3 emitter is the first commercial multinozzle emitter device for mass spectrometry. Our Newomics® services center on the multiomics analyses of small amounts of biological samples including human blood samples, mammalian cells, host cell... Show more »

Newomics Inc., a biotechnology company in the San Francisco Bay Area, commercializes innovative (New) and integrative (Omics) platforms and solutions for personalized healthcare. Our proprietary technology is based on silicon-microfluidic-chip for liquid chromatography-mass spectrometry (LC-MS), and offers unprecedented robustness, sensitivity, specificity, and throughput for analyzing molecules from minute amounts of biospecimens such as blood and urine. Our core technologies are built upon the multinozzle emitter array (MEA) technology, invented from the Lawrence Berkeley National Laboratory (Berkeley Lab), which has won the 2012 R&D 100 award. Our first product Newomics® M3 emitter is the first commercial multinozzle emitter device for mass spectrometry. Our Newomics® services center on the multiomics analyses of small amounts of biological samples including human blood samples, mammalian cells, host cell proteins, CHO cell culture media, and antibody drugs etc. We have established state-of-the-art 2D LC-MS/MS systems including Thermo QE-plus, Thermo Quantiva, and Waters Q-TOF mass spectrometers, as well as a wide range of bioinformatics tools.

Selected Publications

  • "Proteoform-Specific Protein Binding of Small Molecules in Complex Matrices," (2017) ACS Chemical Biology, 12(2), 389-397.
  • "Biomonitoring of Perfluorinated Compounds in a Drop of Blood," (2015) Environmental Science & Technology, 49(11), 6808-6814.
  • "Top-Down Proteomics of a Drop of Blood for Diabetes Monitoring," (2014) Journal of Proteome Research, 13(3), 1560-1569.
  • "Multinozzle Emitter Array Chips for Small-Volume Proteomics," (2013) Analytical Chemistry, 85(2), 816-819.
  • "Multinozzle Emitter Arrays for Nanoelectrospray Mass Spectrometry," (2011) Analytical Chemistry, 83(15), 6082-6089.
  • "Microfabricated Monolithic Multinozzle Emitters for Nanoelectrospray Mass Spectrometry," (2007) Analytical Chemistry, 79(10), 3703-3707.
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Proteomics
Price on request

Newomics provides both Newomics® bottom-up and top-down proteomics services with our proprietary technologies. For the first order, new customers get the first 2 samples free for every 5 samples if 5 or more samples are ordered.
(a) Bottom-up proteomics: identification, label-free quantitation, and pathway analysis of over... Show more »

Newomics provides both Newomics® bottom-up and top-down proteomics services with our proprietary technologies. For the first order, new customers get the first 2 samples free for every 5 samples if 5 or more samples are ordered.
(a) Bottom-up proteomics: identification, label-free quantitation, and pathway analysis of over 3,000 proteins starting from 1-5 x10e5 mammalian cells (e.g., stem cells, cancer cells).
(b) Top-down proteomics: identification and label-free quantitation of a multi-timescale, multi-marker panel for monitoring diabetes and other diseases starting from 5 microliters of human blood samples.
(c) Bioinformatics with the following capabilities:
Proteome Discoverer with Sequest and Mascot search engines;
ProSightPC for top-down MS data search;
BioPharma Finder for intact protein analysis;
Ingenuity Pathway Analysis (IPA).

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Waters Column RP18
Qtof Mass Spectrometry
Quantitative Proteomics
Bioinformatics pipelines
Thermo Fisher Q-Exactive
LC-MS/MS
Lipidomics
Price on request

Newomics provides Newomics® shotgun lipidomics services. For the first order, new customers get the first 5 samples free for every 10 samples if 10 or more samples are ordered.
(a) Identification and absolute quantitation of over 300 lipid species from 15 classes starting from 5 microliter or less of human blood samples.
(b)... Show more »

Newomics provides Newomics® shotgun lipidomics services. For the first order, new customers get the first 5 samples free for every 10 samples if 10 or more samples are ordered.
(a) Identification and absolute quantitation of over 300 lipid species from 15 classes starting from 5 microliter or less of human blood samples.
(b) Bioinformatics with the following capabilities:
Compound Discoverer with mzCloud, ChemSpider, and KEGG pathway search and other customized databases;
TraceFinder for small molecule targeted analysis;
LipidSearch for lipidomics data search and label-free quantitation.

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Waters Column RP18
Qtof Mass Spectrometry
Bioinformatics pipelines
MRM Assay
Thermo Fisher Q-Exactive
LC-MS/MS
Clinical Validation of In Vitro Diagnostics/Companion Diagnostics
Price on request

Newomics is open to a free pilot project for feasibility studies.

Newomics performs NIH-funded studies for many different purposes, such as environmental biomonitoring, natural products R&D, stem cell research, biomarker discovery and screening, and drug screening and discovery (see Selected Publications). These Newomics®... Show more »

Newomics is open to a free pilot project for feasibility studies.

Newomics performs NIH-funded studies for many different purposes, such as environmental biomonitoring, natural products R&D, stem cell research, biomarker discovery and screening, and drug screening and discovery (see Selected Publications). These Newomics® services will be offered to a wide range of clients in different settings including government agencies, universities, biopharmaceutical companies, and hospitals. Additional multiomics services will be offered to meet client's specific R&D needs.

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Human
Mouse
Cancer
Whole blood
Drug discovery
serum
plasma
Bioinformatics pipelines
cancer stem cells
Tumor cells
Diabetes
Biomarker discovery
Biomarker analysis
Alzheimers Disease
Drug Safety and Toxicology
Non-human primates
Omics
Price on request
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Clinical Research
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Biology
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Metabolomics
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Clinical Validation Services
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