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NeuroSolutions Ltd

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Coventry, GB

About NeuroSolutions Ltd

Type: Privately Held

Neurosolutions was founded to provide technically demanding electrophysiology to the biopharmaceutical industry. Our highly qualified team of scientists deliver preclinical research solutions from the single cell right through to the whole animal tailored precisely to our client’s needs.

We are comfortable... Show more »

Neurosolutions was founded to provide technically demanding electrophysiology to the biopharmaceutical industry. Our highly qualified team of scientists deliver preclinical research solutions from the single cell right through to the whole animal tailored precisely to our client’s needs.

We are comfortable working on single fee-for-service contracts right up to multiple member research teams driving forward development programs under FTE agreements or as a working partnership. We incorporate the latest technologies in our pursuit of electrophysiological excellence, and deliver exceptional results ahead of schedule. We also provide animal behavioural and molecular biological services of the highest quality in parallel with our electrophysiological expertise.

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Our Services (58)


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Cell Electrophysiology

Price on request
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Ex vivo Electrophysiology

Price on request

In vitro slice electrophysiology

Almost all brain regions, spinal cord, naïve and model animals, single/dual recordings

In vitro slice electrophysiology

Almost all brain regions, spinal cord, naïve and model animals, single/dual recordings

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In vitro Neurodegeneration Models

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Animal Behavior Studies

Price on request

Combined with electrophysiological experiments, Cerebrasol scientists can offer behavioural test to quantify effects of lead compounds on behavioual endpoints

Combined with electrophysiological experiments, Cerebrasol scientists can offer behavioural test to quantify effects of lead compounds on behavioual endpoints

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Extracellular Recording

Price on request
  • Field excitatory post-synaptic potentials (fEPSPs)
  • Population spikes (PS)
  • Long-Term Potentiation (LTP)
  • Long-Term Depression (LTD)
  • Schaffer-collateral CA1 pathway
  • Medial/lateral perforant dentate gyrus pathway
  • Dentate gyrus CA3 ‘Mossy Fibre’ pathway
  • Transgenic capability
  • Field excitatory post-synaptic potentials (fEPSPs)
  • Population spikes (PS)
  • Long-Term Potentiation (LTP)
  • Long-Term Depression (LTD)
  • Schaffer-collateral CA1 pathway
  • Medial/lateral perforant dentate gyrus pathway
  • Dentate gyrus CA3 ‘Mossy Fibre’ pathway
  • Transgenic capability
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Neuropathic Pain Animal Models

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Visceral Pain Animal Models

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Osteoarthritis Animal Models

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In vivo Electrophysiology

Price on request

In vivo electrophysiology

Almost all brain regions, spinal cord, nerve fibres single fibre level, naïve and model animals

In vivo electrophysiology

Almost all brain regions, spinal cord, nerve fibres single fibre level, naïve and model animals

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Cognitive, Behavioral, and Psychiatric Animal Models

Price on request

Neurosolutions has a wealth of experience in providing first class preclinical translational research into the study, treatment and prevention of mental disorders. Our track record can be demonstrated in our manuscript publications and our key strength is in developing precisely tailored research packages to target out client’s... Show more »

Neurosolutions has a wealth of experience in providing first class preclinical translational research into the study, treatment and prevention of mental disorders. Our track record can be demonstrated in our manuscript publications and our key strength is in developing precisely tailored research packages to target out client’s needs. Whether it is in vitro or in vivo electrophysiological approaches, whole animal behavior or molecular biology techniques, our research teams will provide expert consultancy in putting together the study proposal you require, and our investigators will then rapidly deliver data of the highest quality to drive forward your research programs.

Disease Areas

  • Schizophrenia
  • Depression
  • Anxiety
  • Psychosis

Behavioural Tests

  • Barnes maze
  • Conflict anxiety model (high level illumination & odour)

Electrophysiological Assays

  • In vivo: single unit recordings from hippocampus/ striatum/ substantia nigra/ dorsal raphe/ prefrontal cortex / brainstem Local field potential/population spike recording from hippocampus; CA1/DG/CA3, LTP, MEA
  • In vitro: whole-cell patch-clamp recordings from brain slices (current/voltage/blind/visualised)
  • Local field potentials – spontaneous and evoked extracellular recordings from brain slices, including LTP/LTD and multi-electrode recording (MEA) Ion channel pharmacology – state-dependency, kinetics, and site of action using cultured and primary dissociated neurones, cell lines
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Custom Pain Animal Models

Price on request

Neurosolutions has established expertise in delivering first class preclinical translational research into pain, particularly around the development of new treatments into neuropathic and inflammatory pain.

Our track record can be demonstrated in our manuscript publications and our key strength is in developing precisely... Show more »

Neurosolutions has established expertise in delivering first class preclinical translational research into pain, particularly around the development of new treatments into neuropathic and inflammatory pain.

Our track record can be demonstrated in our manuscript publications and our key strength is in developing precisely tailored research packages to target out client’s needs. Whether through using in vitro or in vivo electrophysiological approaches to establish mechanism, using whole animal behavior in one of our many pain models to screen compounds, or using molecular biology techniques to better understand function, our research teams will provide expert consultancy in putting together the study proposal you require, and our investigators will then rapidly deliver data of the highest quality to drive forward your research programs.

Diesease Areas

  • Chronic constriction injury
  • Spinal nerve ligation
  • Diabetes-induced
  • Chemotherapy-induced
  • Fracture pain model
  • Carrageenan
  • Complete Freund’s adjuvant
  • Formalin
  • MIA
  • UVB
  • Surgical pain

Behavioural Tests

  • Von Frey hair
  • Hargreave’s
  • Randall-Selitto
  • Weight-bearing
  • Paw licking, shaking, lifting
  • Plethysmography
  • RotaRod test

Electrophysiological Assays

  • In vivo: Single fibre recording, spontaneous and evoked, single neurone recording from the spinal cord and brain, all naïve and modelled animals
  • In vitro: Compound action potential recording from isolated nerves, naïve and modelled, slice patch-clamp recordings, dissociated DRG patch-clamp recordings from naïve and modelled animals
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Circadian Profiling Animal Models

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Neurodegeneration Animal Models

Price on request

Neurosolutions has extensive experience in delivering first class preclinical translational research into the study, treatment and prevention of neurodegenerative disorders, particularly around amyloid based animal models of Alzheimer’s disease.

Our track record is demonstrated in our manuscript publications and our key... Show more »

Neurosolutions has extensive experience in delivering first class preclinical translational research into the study, treatment and prevention of neurodegenerative disorders, particularly around amyloid based animal models of Alzheimer’s disease.

Our track record is demonstrated in our manuscript publications and our key strength is in developing precisely tailored research packages to target out client’s needs. Whether it is in vitro or in vivo electrophysiological approaches, whole animal behavior or molecular biology techniques, our research teams will provide expert consultancy in putting together the study proposal you require, and our investigators will then rapidly deliver data of the highest quality to drive forward your research programs.

Disease Areas

  • Alzheimer’s Disease
  • Parkinson’s Disease
  • Multiple Sclerosis
  • Huntington’s Disease

Behavioural Tests

  • Open field: e.g. object recognition test (ORT), Y-maze, Barnes maze
  • Operant chambers: e.g. Alternating Lever Cyclic Ratio (ALCR), delayed match-to-position (DMTP/DNMTP)
  • Beta-amyloid induced deficits (ADDL/APP/oligomers/aggregated) α-synuclein-induced deficits
  • Commercially available transgenic rodent models

Electrophysiological Assays

  • In vivo: single cells – extra and intracellular recording; iontophoretic, central and parenteral drug administration
  • Local field potentials – spontaneous and evoked, including LTP/LTD
  • Peripheral nerves – compound and single fibre
  • Telemetric and multi-electrode recording
  • In vitro: whole-cell patch-clamp recordings from brain slices (current/voltage/blind/visualised)
  • Local field potentials – spontaneous and evoked extracellular recordings from brain slices, including LTP/LTD and multi-electrode recording (MEA)
  • Ion channel pharmacology – state-dependency, kinetics, and site of action using cultured and primary dissociated neurones, cell lines
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Schizophrenia Animal Models

Price on request
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Alzheimer's Disease Animal Models

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Electroencephalogram (EEG) Models

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Epilepsy & Seizure Animal Models

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Huntington's Disease Animal Models

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Obesity Animal Models

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Diabetes Animal Models

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Cell-Based Assays

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Animal Model in vivo Analyses

Price on request

Animal Model in vivo Analyses Services

Animal Model in vivo Analyses Services

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Animal Cognition & Behavior Tests

Price on request

Animal Cognition & Behavior Tests Services

Animal Cognition & Behavior Tests Services

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Animal Learning, Memory, and Behavior Tests

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Animal Learning, Memory, and Behavior Tests Services

Animal Learning, Memory, and Behavior Tests Services

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Metabolic Animal Models

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Neuroscience

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Pain/Neuropathy Animal Models

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Animal in vivo Imaging

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Analgesic Animal Models

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Animal Models and Studies

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Lead Identification and Validation

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Bone/Cartilage Animal Models

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Biology

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In vitro Disease Models

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CNS/Neurology Animal Models

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Drug Discovery & Development

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Assay Development

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Drug Target Validation

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Electrophysiology Animal Models

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Ion Channel Screening Assays

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In vitro Diabetes Models

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Cognition and Behavior Animal Models

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Parkinsons Disease Animal Models

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Neuroscience Animal Models

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Acute Inflammatory Pain Animal Models

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Depression Animal Models

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Anxiety Animal Models

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In vitro Neural Models

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Sodium Channel Assays

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Potassium Channel Assays

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Calcium Channel Assays

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Chloride Channel Assays

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Optogenetics Studies

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In vitro Ion Channel Assays

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Animal Models of Disease

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Drug Discovery

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Cells and Tissues

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Project Management

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