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Neurofit

ILLKIRCH, Grand Est, FR

NEUROFIT is a preclinical Contract Research Organization (CRO) specialising in the evaluation of treatments for central and peripheral nervous system disorders.

We offer a comprehensive list of in vitro and in vivo models covering a wide range of indications.

NEUROFIT aims to facilitate your preclinical drug development by proposing the best models for your needs. Our goal is to accelerate the development of your programs by providing cost-effective methods for compound evaluation.

Neurofit has not listed any services.

In vitro Excitotoxicity Models
Price on request

Pathological process by which nerve cells are damaged or killed by excessive stimulation by neurotransmitters such as glutamate and similar substances. This occurs when receptors for the excitatory neurotransmitter glutamate such as the NMDA receptor are overactivated.

  • Excitotoxicity on cortical neurons

Pathological process by which nerve cells are damaged or killed by excessive stimulation by neurotransmitters such as glutamate and similar substances. This occurs when receptors for the excitatory neurotransmitter glutamate such as the NMDA receptor are overactivated.

  • Excitotoxicity on cortical neurons
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Mouse
Rodents
Spinal Cord Injury Models
Price on request

Neurofit can evaluate the neuroprotective or neurotrophic effect of your compounds dedicated to the prevention or cure of spinal cord injuries.

  • Neurite outgrowth
  • Nerve / Muscle co-culture

Neurofit can evaluate the neuroprotective or neurotrophic effect of your compounds dedicated to the prevention or cure of spinal cord injuries.

  • Neurite outgrowth
  • Nerve / Muscle co-culture
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Neuronal Assays
Price on request

Today, growing interest has shifted to the reactivation of a juvenile-like plasticity in the brain for the treatment of depression. To be in line with this development concept, NEUROFIT proposes neuronal neurite outgrowth assay to demonstrate the effect of your antidepressant compounds.

  • Cortical neurons : neurite outgrowth
  • iPSC-derived neurons : neurite outgrowth

Today, growing interest has shifted to the reactivation of a juvenile-like plasticity in the brain for the treatment of depression. To be in line with this development concept, NEUROFIT proposes neuronal neurite outgrowth assay to demonstrate the effect of your antidepressant compounds.

  • Cortical neurons : neurite outgrowth
  • iPSC-derived neurons : neurite outgrowth
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In vitro Neurodegeneration Models
Price on request

One of the strategies mostly used by pharmaceutical industries to prevent or repair neurodegeneration is based on the development of neuroprotectant or neurotrophic compounds. NEUROFIT implements different cellular models to assess the efficacy of these classes of compounds.

  • Neurite outgrowth
  • Survival and Viability
  • Basal Amyloid β production

One of the strategies mostly used by pharmaceutical industries to prevent or repair neurodegeneration is based on the development of neuroprotectant or neurotrophic compounds. NEUROFIT implements different cellular models to assess the efficacy of these classes of compounds.

  • Neurite outgrowth
  • Survival and Viability
  • Basal Amyloid β production
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In vitro Neurotoxicity Testing
Price on request
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Animal Electromyography
Price on request

Sensorimotor deficit is observed under various diseases that affect the nervous system.

  • NERVE FUNCTION : SNCV
  • NEUROMUSCULAR FUNCTION : CMAP

Sensorimotor deficit is observed under various diseases that affect the nervous system.

  • NERVE FUNCTION : SNCV
  • NEUROMUSCULAR FUNCTION : CMAP
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Histomorphometric Analysis
Price on request

Study of the microscopic organization and structure of a tissue (as skin, nerve) by computer-assisted analysis of images formed by a microscope

  • IENF
  • MYELIN THICKNESS : g-ratio
  • AXON CALIBER / DISTRIBUTION

Study of the microscopic organization and structure of a tissue (as skin, nerve) by computer-assisted analysis of images formed by a microscope

  • IENF
  • MYELIN THICKNESS : g-ratio
  • AXON CALIBER / DISTRIBUTION
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Toxicity Animal Model
Price on request

Preclinical investigations of the toxicity of a compound represent a crucial step in the drug development process before eventual administration in humans. NEUROFIT has received ethics approval to conduct these studies.

Preclinical investigations of the toxicity of a compound represent a crucial step in the drug development process before eventual administration in humans. NEUROFIT has received ethics approval to conduct these studies.

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Mouse
Rat
Animal Motor Function Tests
Price on request

Sensori-motor deficits are implied in a wide range of CNS and PNS diseases. NEUROFIT proposes different tests to study the influence of your compounds in sensori-motor deficit.

  • Open-Field
  • Rotarod
  • DWB
  • Beam Walking
  • Cylinder test
  • Wire-hanging

Sensori-motor deficits are implied in a wide range of CNS and PNS diseases. NEUROFIT proposes different tests to study the influence of your compounds in sensori-motor deficit.

  • Open-Field
  • Rotarod
  • DWB
  • Beam Walking
  • Cylinder test
  • Wire-hanging
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Pain/Neuropathy Animal Models
Price on request

NEUROFIT implements different models and tests to evaluate compounds acting on different types of pain. Feel free to contact our experts to discuss about the most relevant test you could apply for your studies.

  • Hot Plate
  • DWB
  • Paw Pressure
  • Tail-Flick

NEUROFIT implements different models and tests to evaluate compounds acting on different types of pain. Feel free to contact our experts to discuss about the most relevant test you could apply for your studies.

  • Hot Plate
  • DWB
  • Paw Pressure
  • Tail-Flick
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Animal Anxiety and Depression Tests
Price on request

NEUROFIT provides different tests to evaluate the efficacy of your compounds. As each test implying anxiety and depression assessment is specific, we attach a great importance to the prior discussion to propose you the most relevant solution to answer to your question.

  • Marble Burying
  • Forced Swimming test
  • Elevated Plus Maze
  • Light-Dark test

NEUROFIT provides different tests to evaluate the efficacy of your compounds. As each test implying anxiety and depression assessment is specific, we attach a great importance to the prior discussion to propose you the most relevant solution to answer to your question.

  • Marble Burying
  • Forced Swimming test
  • Elevated Plus Maze
  • Light-Dark test
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Cognition and Behavior Animal Models
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Novel Object Recognition Test
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Animal Models and Studies
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Animal Model in vivo Analyses
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Animal Cognition & Behavior Tests
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Animal Learning, Memory, and Behavior Tests
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Animal Models of Disease
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Cognitive, Behavioral, and Psychiatric Animal Models
Price on request

NEUROFIT offers several cognition test to assess the efficacy of your compounds. All our tests are run routinely by our experts who are also available to provide you advices in the design of your experiment. Our goal is to provide you the most relevant data following your needs.

  • T-Maze
  • Passive Avoidance
  • Novel Object Recognition

NEUROFIT offers several cognition test to assess the efficacy of your compounds. All our tests are run routinely by our experts who are also available to provide you advices in the design of your experiment. Our goal is to provide you the most relevant data following your needs.

  • T-Maze
  • Passive Avoidance
  • Novel Object Recognition
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Biology
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Cells and Tissues
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In vitro Disease Models
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Drug Discovery & Development
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Drug Discovery & Development Services

Drug Discovery & Development Services

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Pharmacology & Toxicology
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Pharmacology & Toxicology Services

Pharmacology & Toxicology Services

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Toxicology
Price on request

Toxicology Services

Toxicology Services

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In vivo Toxicity Testing
Price on request

In vivo Toxicity Testing Services

In vivo Toxicity Testing Services

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Clinical Research
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Clinical Research Services

Clinical Research Services

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Clinical Laboratory Services
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Clinical Laboratory Services

Clinical Laboratory Services

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Clinical and Anatomic Pathology
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Clinical and Anatomic Pathology Services

Clinical and Anatomic Pathology Services

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Animal Imaging
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Animal Imaging Services

Animal Imaging Services

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In vitro Toxicity Testing
Price on request

In vitro Toxicity Testing Services

In vitro Toxicity Testing Services

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Cell-Based Assays
Price on request

Cell-Based Assays Services

Cell-Based Assays Services

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Functional & Cell Type Specific Assays
Price on request

Functional & Cell Type Specific Assays Services

Functional & Cell Type Specific Assays Services

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CNS/Neurology Animal Models
Price on request

CNS/Neurology Animal Models Services

CNS/Neurology Animal Models Services

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2018-11-01 06:14:22 -0700

Net Promoter Score of 8 received for Neuronal Assays.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 10.
November 1, 2018

Positive review received for Neuronal Assays:

"Rapid communication, initiation of study and turn around of report. Very easy interactions and would use again. Thanks."

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