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Nanosyn

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ic 7 Orders Completed
Santa Clara, California, US

About Nanosyn

Nanosyn, provider of Discovery on Demand services, is a medicinal chemistry and biological services contract research organization providing made-to-order focused compound libraries, hit-to-lead optimization, medicinal chemistry services and other innovative solutions to meet your drug discovery needs.

Our... Show more »

Nanosyn, provider of Discovery on Demand services, is a medicinal chemistry and biological services contract research organization providing made-to-order focused compound libraries, hit-to-lead optimization, medicinal chemistry services and other innovative solutions to meet your drug discovery needs.

Our proprietary technology allows us to provide superior chemistry and biology services that effectively accelerate the drug discovery process for biotechnology and pharmaceutical companies worldwide.

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Our Services (20)


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Cell-Based Compound Screening

Price on request

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary... Show more »

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary version of an advanced microfluidic screening platform. Custom enzymatic assays for new targets can be developed.

Advantages:

• data more precise and reproducible than from other screening methods allowing for direct and immediate SAR mining
• direct measurement of enzyme activity accurately identifies inhibitors and activators in the same run
• true selectivity determinations delivered via comparable biochemical and kinetic conditions across the suite of targets
• rigorous quality control principles including reference compounds run with every data set
• very low level of false positive and false negatives
• data reporting customized to your needs
• rapid turnaround time

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Compound Profiling

Price on request

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary... Show more »

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary version of an advanced microfluidic screening platform. Custom enzymatic assays for new targets can be developed.

Advantages:

• data more precise and reproducible than from other screening methods allowing for direct and immediate SAR mining
• direct measurement of enzyme activity accurately identifies inhibitors and activators in the same run
• true selectivity determinations delivered via comparable biochemical and kinetic conditions across the suite of targets
• rigorous quality control principles including reference compounds run with every data set
• very low level of false positive and false negatives
• data reporting customized to your needs
• rapid turnaround time

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Enzyme Assays

Price on request

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary... Show more »

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary version of an advanced microfluidic screening platform. Custom enzymatic assays for new targets can be developed.

Advantages:

• data more precise and reproducible than from other screening methods allowing for direct and immediate SAR mining
• direct measurement of enzyme activity accurately identifies inhibitors and activators in the same run
• true selectivity determinations delivered via comparable biochemical and kinetic conditions across the suite of targets
• rigorous quality control principles including reference compounds run with every data set
• very low level of false positive and false negatives
• data reporting customized to your needs
• rapid turnaround time

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Medicinal Chemistry

Price on request

Chemistry-on-demand, based on Nanosyn's patented techniques, includes know-how, chemical synthesis, software and instrumentation designed to generate novel, pure, and well characterized compounds.

Nanosyn offers:
• medicinal chemistry
• synthetic chemistry
• hit-to-lead
• fragment based lead
• focused... Show more »

Chemistry-on-demand, based on Nanosyn's patented techniques, includes know-how, chemical synthesis, software and instrumentation designed to generate novel, pure, and well characterized compounds.

Nanosyn offers:
• medicinal chemistry
• synthetic chemistry
• hit-to-lead
• fragment based lead
• focused library
• custom synthesis

Advantages include:
• reduced iterative cycle time
• array of highly purified small molecule compounds
• maximum flexibility in synthesis (solid phase, solution phase, microwave assisted chemistry, inert atmosphere etc...)
• highly efficient compound production (from mg to Kg in cGMP unit)
• HTS characterization and proprietary systems for data processing

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Kinase Assays

Price on request
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Kinase Assay Development

Price on request
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High Throughput Screening (HTS)

Price on request
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Epigenetic Assay Development

Price on request
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Drug Development

Price on request
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Compound Libraries

Price on request
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Assay Development

Price on request
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Biochemical Assays

Price on request
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Biochemistry & Molecular Biology

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Drug Discovery & Development

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Project Management

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Lead Identification and Validation

Price on request
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Hit Identification

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DNA Services

Price on request
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Nucleic Acid Services

Price on request
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Epigenetic Studies

Price on request
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