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Nanosyn

Santa Clara, California, US

Nanosyn, provider of Discovery on Demand services, is a medicinal chemistry and biological services contract research organization providing made-to-order focused compound libraries, hit-to-lead optimization, medicinal chemistry services and other innovative solutions to meet your drug discovery needs.

Our proprietary technology allows us to provide superior chemistry and biology services that effectively accelerate the drug discovery process for biotechnology and pharmaceutical companies worldwide.

Nanosyn has not listed any services.

Cell-Based Compound Screening
Price on request

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary... Show more »

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary version of an advanced microfluidic screening platform. Custom enzymatic assays for new targets can be developed.

Advantages:

• data more precise and reproducible than from other screening methods allowing for direct and immediate SAR mining
• direct measurement of enzyme activity accurately identifies inhibitors and activators in the same run
• true selectivity determinations delivered via comparable biochemical and kinetic conditions across the suite of targets
• rigorous quality control principles including reference compounds run with every data set
• very low level of false positive and false negatives
• data reporting customized to your needs
• rapid turnaround time

« Show less
Compound Profiling
Price on request

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary... Show more »

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary version of an advanced microfluidic screening platform. Custom enzymatic assays for new targets can be developed.

Advantages:

• data more precise and reproducible than from other screening methods allowing for direct and immediate SAR mining
• direct measurement of enzyme activity accurately identifies inhibitors and activators in the same run
• true selectivity determinations delivered via comparable biochemical and kinetic conditions across the suite of targets
• rigorous quality control principles including reference compounds run with every data set
• very low level of false positive and false negatives
• data reporting customized to your needs
• rapid turnaround time

« Show less
Enzyme Assays
Price on request

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary... Show more »

Nanosyn offers Screening, Profiling and Mechanistic studies for all types of enzymatic targets:

• kinases (>300 different wild types)
• epigenetic targets (KDMs, HMTs, HDAC/SIRTs, HAT)
• phosphatases
• proteases
• phosphodiesterases

The functional assays are developed and performed using a proprietary version of an advanced microfluidic screening platform. Custom enzymatic assays for new targets can be developed.

Advantages:

• data more precise and reproducible than from other screening methods allowing for direct and immediate SAR mining
• direct measurement of enzyme activity accurately identifies inhibitors and activators in the same run
• true selectivity determinations delivered via comparable biochemical and kinetic conditions across the suite of targets
• rigorous quality control principles including reference compounds run with every data set
• very low level of false positive and false negatives
• data reporting customized to your needs
• rapid turnaround time

« Show less
Medicinal Chemistry
Price on request

Chemistry-on-demand, based on Nanosyn's patented techniques, includes know-how, chemical synthesis, software and instrumentation designed to generate novel, pure, and well characterized compounds.

Nanosyn offers:
• medicinal chemistry
• synthetic chemistry
• hit-to-lead
• fragment based lead
• focused... Show more »

Chemistry-on-demand, based on Nanosyn's patented techniques, includes know-how, chemical synthesis, software and instrumentation designed to generate novel, pure, and well characterized compounds.

Nanosyn offers:
• medicinal chemistry
• synthetic chemistry
• hit-to-lead
• fragment based lead
• focused library
• custom synthesis

Advantages include:
• reduced iterative cycle time
• array of highly purified small molecule compounds
• maximum flexibility in synthesis (solid phase, solution phase, microwave assisted chemistry, inert atmosphere etc...)
• highly efficient compound production (from mg to Kg in cGMP unit)
• HTS characterization and proprietary systems for data processing

« Show less
Kinase Assays
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Kinase Assay Development
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High Throughput Screening
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Epigenetic Assay Development
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Drug Development
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Compound Libraries
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Assay Development
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Biochemical Assays
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Biochemistry & Molecular Biology
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Drug Discovery & Development
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Project Management & Consulting Services
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Lead Identification and Validation
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Hit Identification
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DNA
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Nucleic Acid Services
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Epigenetic Analysis
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2017-08-08 19:51:18 -0400

Net Promoter Score of 8 received for Enzyme Assays.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 8.

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