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Nanopharm Ltd

1 Order Completed
Newport, GB

About Nanopharm Ltd

We are the world’s leading provider of orally inhaled and nasal drug product design and development services.

We enable the seamless translation of pre-clinical development through to clinical manufacture of OINDPs through our unique processing technologies and formulation development tools. Our integrated... Show more »

We are the world’s leading provider of orally inhaled and nasal drug product design and development services.

We enable the seamless translation of pre-clinical development through to clinical manufacture of OINDPs through our unique processing technologies and formulation development tools. Our integrated development services in materials characterisation, formulation development and inhaled biopharmaceutics aids successful product development of OINDPs by understanding how material properties and processing conditions influence product functionality.
We are the market leaders in providing bespoke solutions to the development of OINDPs. Our technology platforms for advanced materials characterisation, formulation & device development, together with in silico modelling of OINDP in vivo behaviour, is acknowledged as cutting edge and market leading.

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Our Services (7)


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Drug Preformulation

Price on request

We can provide you with the solid foundation required for successful transition of early phase development programs, using our world-leading expertise in pre-formulation development of methods for inhaled drug product characterisation.

We understand poor pre-formulation studies may lead to delays in pre-clinical and clinical... Show more »

We can provide you with the solid foundation required for successful transition of early phase development programs, using our world-leading expertise in pre-formulation development of methods for inhaled drug product characterisation.

We understand poor pre-formulation studies may lead to delays in pre-clinical and clinical development programs. We can provide you with the solid foundation required for successful transition of early phase development programs through to clinical, using our world-leading expertise in development of methods for inhaled drug product characterisation, As part of our pre-formulation development package we are able to provide you with the following:

  • Development of assay and stability indicating methods by HPLC/UPLC/LC-MS-MS
  • Conduct force degradation studies.
  • Excipient compatibility studies.
  • Develop methods for determining blend content uniformity of dry powder formulation blends.
  • Develop methods for delivered dose uniformity and aerodynamic particle size distribution by inertial impaction.
  • Conduct ICH based stability testing of APIs and finished products.
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Product Development Consulting

Price on request

You will have access to our extensive expertise in developing orally inhaled and nasal drug products,
from the lab through to the clinic and product registration.

Product development starts with defining the critical material attributes (CMAs) of the device and formulation. This enables pre-selection of lead formulations and... Show more »

You will have access to our extensive expertise in developing orally inhaled and nasal drug products,
from the lab through to the clinic and product registration.

Product development starts with defining the critical material attributes (CMAs) of the device and formulation. This enables pre-selection of lead formulations and processes to best meet the defined target product profile. These formulations and processes are screened to identify critical quality attributes that impact drug product performance. Both formulations and processes are challenged and optimised to ensure that the drug product can be manufactured using the Quality by Design paradigm.

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Material Testing Services

Price on request

Our advanced analytical characterisation services and our understanding of how input material physico-chemical and mechanical properties affect product specification, functionality and stability of orally inhaled and nasal drug products was the foundation of our company.

Therefore we have developed a range of novel technologies... Show more »

Our advanced analytical characterisation services and our understanding of how input material physico-chemical and mechanical properties affect product specification, functionality and stability of orally inhaled and nasal drug products was the foundation of our company.

Therefore we have developed a range of novel technologies for characterising critical material attributed of APIs and excipients and control methodologies required for optimising crystals, particles and powders for OINDPs.

These are accessible through our NANOPLEX service offering that include:

  • Mechanical properties of primary crystals.
  • Particle characterisation (particle size, surface area, morphology, crystalline form).
  • Levels of surface structural disorder created upon micronisation.
  • Direct measurement of the relative magnitude of interparticulate forces that control formulation structure and functionality.
  • Structural and interfacial stability of APIs post-micronisation.
  • Powder rheometry measurements of powder formulations.

These tools have enabled us to characterise and address common pharmaceutical processing issues that include:

  • API batch-to-batch processing variability
  • API changes during scale-up
  • API stability post-micronisation
  • Fingerprinting and evaluating third-party sourced APIs
  • Lagering or conditioning requirements for stabilising APIs
  • The ability to predict and optimise microstructure and product functionality
  • Control methodologies required to maintain optimum control of surface and interfacial properties of materials.
  • Critical material attributes of excipients.
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Formulation Services

Price on request

You can benefit from a range of tailored and robust formulation development solutions for all types of pMDIs and DPI device platforms, through our INTERHALE technologies.

Orally inhaled and nasal drug products are complex systems that are highly dependent on interactions between device and formulation components.

Our... Show more »

You can benefit from a range of tailored and robust formulation development solutions for all types of pMDIs and DPI device platforms, through our INTERHALE technologies.

Orally inhaled and nasal drug products are complex systems that are highly dependent on interactions between device and formulation components.

Our specialist understanding of the critical material attributes of devices, APIs and excipients enables pre-selection of lead formulations and process requirements to best meet a defined target product profile.

Formulations and processes are subsequently screened to identify critical quality attributes that impact drug product performance. Both formulations and processes are challenged and optimised to ensure that the drug product can be manufactured using the Quality by Design paradigm.

Our extensive expertise has enabled companies to accelerate early phase development programs and expedite first-in-human and proof of concept clinical trials.

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Chemistry and Materials

Price on request

Chemistry and Materials Services

Chemistry and Materials Services

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Analytical Chemistry Services

Price on request

Analytical Chemistry Services

Analytical Chemistry Services

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Product Development, Testing, and Packaging

Price on request

Product Development, Testing, and Packaging Services

Product Development, Testing, and Packaging Services

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