Najmanovich Research Group

Modelling RNA and Proteins, Molecular Dynamics simulations, Elastic Network Models, Prediction of the effect of mutations on flexibility and thermal stability of proteins, prediction of protein non-structured regions, conformational sampling, prediction of binding sites, molecular similarity analysis, detection of potential cross-reactivity targets based on binding-site similarities, etc.

High-throughput virtual screening of custom made small-molecule or peptide libraries

codon usage & optimization. Analysis of rare codons, optimization of codons for cloning projects.

Analysis of sequence conservation

Reconstruction of metabolic networks, Flux Balance Analysis, Synthetic Accessibility, prediction of gene essentiality.

Large-scale biological data analysis

Monte-Carlo, Genetic Algorithms, Neural Networks, Decision Trees, Graph theory, etc