1383673403023 09e9b1cc6b7c5c0744dc9f68973ea6ea

Mutation Generation and Detection Facility

Salt Lake City, Utah, US

The Mutation Generation and Detection Facility specializes in providing custom TALEN and Crispr-Cas9 DNA nucleases to induce targeted mutations in a genomic region of your interest. TALEN and Crispr-Cas9 DNA nucleases are a cutting edge technology for performing reverse genetic studies in multiple model systems, including, but not limited to Zebrafish, Drosophila, C. elegans, mouse and other mammalian tissue culture. If you are looking to activate expression of your gene from its native locus our Core provides customized TALE activator proteins for this purpose.

The Genetic Mutation and Detection Core also offers services to identify induced mutations using High Resolution Melt Analysis (HRMA). Our support includes hardware, reagents, and expert advice for optimizing and performing HRMA for your gene of interest.

Instrumentation: basic molecular bio instruments, for mutation detection Eppendorf PCR machine

Mutation Generation and Detection Facility has not listed any services.

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CRISPR/Cas9 vector generation
Starting at $375.00 per clone

The Utah Mutation Generation and Detection Core Facility provides custom Crispr Constructs in multiple forms for use in multiple model organisms. Service includes design of optimal target sites, off target analysis, and delivery of sequence verified vectors. The Core will also assist in the design and implementation of... Show more »

The Utah Mutation Generation and Detection Core Facility provides custom Crispr Constructs in multiple forms for use in multiple model organisms. Service includes design of optimal target sites, off target analysis, and delivery of sequence verified vectors. The Core will also assist in the design and implementation of experiments.


Pricing (per plasmid pair):

Non-Profit Researchers Basic CRISPR Services
• 1X CRISPR design and construction $375.00

CRISPR Bulk Ordering Pricing for Non-Profit Researchers
• >2 CRISPR design and construction $346.00
• >4 CRISPR design and construction $318.00
• >6 CRISPR design and construction $290.00
• >8 CRISPR design and construction $262.00
• >10 CRISPR design and construction $234.00


Turn-around time: under 1 week


Sample requirements:
- known gene information
- sequence to target


Deliverables:
- 45ul of mini prep
- full sequence

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TALEN Genome Editing
Starting at $1,125.00 per clone

The Utah Mutation Generation and Detection Core Facility provides custom TALEN Constructs in multiple forms for use in multiple model organisms. Service includes design of optimal target sites, off target analysis, and delivery of sequence verified vectors. The Core will also assist in the design and implementation of... Show more »

The Utah Mutation Generation and Detection Core Facility provides custom TALEN Constructs in multiple forms for use in multiple model organisms. Service includes design of optimal target sites, off target analysis, and delivery of sequence verified vectors. The Core will also assist in the design and implementation of experiments.


Pricing (per plasmid pair):

Custom TALEN Protein Services:
• TALEN plasmid pair design and construction $1125.00
• 2X TALEN plasmid pair design and construction $2100.00
• TALE activator plasmid design and construction $560.00

Bulk TALEN Ordering Rates:
• 5 or more TALEN plasmid pair design and construction $1000.00
• 10 or more TALEN plasmid pair design and construction $950.00
• 15 or more TALEN plasmid pair design and construction $900.00


Turn-around time: under 3 weeks

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Zebrafish Genome Editing
Starting at $1,125.00 per clone
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Biology
Price on request
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Genetic Engineering
Price on request
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Zebrafish Transgenic Services
Price on request
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DNA
Price on request
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Plasmids and Vectors
Price on request
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Biochemistry & Molecular Biology
Price on request
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Nucleic Acid Services
Price on request
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October 22, 2015

Positive review received for TALEN Genome Editing:

"They are really helpful and give very detailed explanation. They also updated the progress of the products once a week."

March 18, 2014

Positive review received for Transgenic Animal Model Development:

"Enjoyed this project and am starting a new one!"

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2015-04-09 12:39:46 +0800

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