1383673403023 09e9b1cc6b7c5c0744dc9f68973ea6ea

Mutation Generation and Detection Facility

100% Positive
20 Orders Completed
Salt Lake City, Utah, US

About Mutation Generation and Detection Facility

Divison of: University of Utah

The Mutation Generation and Detection Facility specializes in providing custom TALEN and Crispr-Cas9 DNA nucleases to induce targeted mutations in a genomic region of your interest. TALEN and Crispr-Cas9 DNA nucleases are a cutting edge technology for performing reverse genetic studies in multiple model... Show more »

The Mutation Generation and Detection Facility specializes in providing custom TALEN and Crispr-Cas9 DNA nucleases to induce targeted mutations in a genomic region of your interest. TALEN and Crispr-Cas9 DNA nucleases are a cutting edge technology for performing reverse genetic studies in multiple model systems, including, but not limited to Zebrafish, Drosophila, C. elegans, mouse and other mammalian tissue culture. If you are looking to activate expression of your gene from its native locus our Core provides customized TALE activator proteins for this purpose.

The Genetic Mutation and Detection Core also offers services to identify induced mutations using High Resolution Melt Analysis (HRMA). Our support includes hardware, reagents, and expert advice for optimizing and performing HRMA for your gene of interest.

Instrumentation: basic molecular bio instruments, for mutation detection Eppendorf PCR machine

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Our Services (10)


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CRISPR/Cas9 Vector Construction

Starting at $375.00 per clone

The Utah Mutation Generation and Detection Core Facility provides custom Crispr Constructs in multiple forms for use in multiple model organisms. Service includes design of optimal target sites, off target analysis, and delivery of sequence verified vectors. The Core will also assist in the design and implementation of... Show more »

The Utah Mutation Generation and Detection Core Facility provides custom Crispr Constructs in multiple forms for use in multiple model organisms. Service includes design of optimal target sites, off target analysis, and delivery of sequence verified vectors. The Core will also assist in the design and implementation of experiments.


Pricing (per plasmid pair):

Non-Profit Researchers Basic CRISPR Services
• 1X CRISPR design and construction $375.00

CRISPR Bulk Ordering Pricing for Non-Profit Researchers
• >2 CRISPR design and construction $346.00
• >4 CRISPR design and construction $318.00
• >6 CRISPR design and construction $290.00
• >8 CRISPR design and construction $262.00
• >10 CRISPR design and construction $234.00


Turn-around time: under 1 week


Sample requirements:

  • known gene information
  • sequence to target

Deliverables:

  • 45ul of mini prep
  • full sequence
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TALEN Design and Validation

Starting at $1,125.00 per clone

The Utah Mutation Generation and Detection Core Facility provides custom TALEN Constructs in multiple forms for use in multiple model organisms. Service includes design of optimal target sites, off target analysis, and delivery of sequence verified vectors. The Core will also assist in the design and implementation of... Show more »

The Utah Mutation Generation and Detection Core Facility provides custom TALEN Constructs in multiple forms for use in multiple model organisms. Service includes design of optimal target sites, off target analysis, and delivery of sequence verified vectors. The Core will also assist in the design and implementation of experiments.


Pricing (per plasmid pair):

Custom TALEN Protein Services:
• TALEN plasmid pair design and construction $1125.00
• 2X TALEN plasmid pair design and construction $2100.00
• TALE activator plasmid design and construction $560.00

Bulk TALEN Ordering Rates:
• 5 or more TALEN plasmid pair design and construction $1000.00
• 10 or more TALEN plasmid pair design and construction $950.00
• 15 or more TALEN plasmid pair design and construction $900.00


Turn-around time: under 3 weeks

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Zebrafish Genome Editing

Starting at $1,125.00 per clone
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Genetic Engineering

Price on request
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DNA Services

Price on request
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Zebrafish Transgenic Services

Price on request
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Biology

Price on request
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Nucleic Acid Services

Price on request
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Biochemistry & Molecular Biology

Price on request
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Plasmids and Vectors

Price on request
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Crystal Davey

Director
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