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MPI Research - Translational Imaging Center

Mattawan, Michigan, US

MPI Research is a full drug development contract research organization with the world’s largest single-site preclinical facility. Our Sponsors benefit from our full suite of preclinical research services.

Our Sponsors value our collaborative culture that is uniformly committed to helping them move their compounds from bench to regulatory filing with accuracy, quality, and speed. Our experienced staff is flexible in adapting to changes and quickly responds to challenges as they arise.

MPI Research insists on the highest quality professional standards across all services and at all levels, and is in full compliance with international, federal, and state regulatory agencies. We are

  • Fully AAALAC accredited
  • In compliance with all FDA, EPA, EMEA, OECD, ICH, and JMHW guidances and regulations
  • Dedicated to quality performance and continuous improvement, with registered QA professionals (RQAP-GLP) and on-staff... Show more »

MPI Research is a full drug development contract research organization with the world’s largest single-site preclinical facility. Our Sponsors benefit from our full suite of preclinical research services.

Our Sponsors value our collaborative culture that is uniformly committed to helping them move their compounds from bench to regulatory filing with accuracy, quality, and speed. Our experienced staff is flexible in adapting to changes and quickly responds to challenges as they arise.

MPI Research insists on the highest quality professional standards across all services and at all levels, and is in full compliance with international, federal, and state regulatory agencies. We are

  • Fully AAALAC accredited
  • In compliance with all FDA, EPA, EMEA, OECD, ICH, and JMHW guidances and regulations
  • Dedicated to quality performance and continuous improvement, with registered QA professionals (RQAP-GLP) and on-staff Lean Six Sigma Blackbelts
  • Continually conducting inspections of GLP and Bioequivalence studies and reports
  • Committed to conducting ongoing operational and subcontractor audits

MPI Research's Translational Imaging Center offers services in molecular imaging and radiochemistry. Molecular imaging has become an indispensable tool in evaluating the biological impact of drug and chemical compounds. Through ongoing investment in equipment and expertise, along with our ability to apply them, MPI Research professionally applies imaging technology to advance knowledge that impacts all phases of the drug development process. Our commitment to our Sponsors is to
exceed their expectations and anticipate their programmatic needs for successful entity development. To that end, we have formed a formal partnership with our long-standing collaborators whose capabilities enhance our own, integrated them, and established the MPI Research Translational Imaging Center.

The 10,000 square-foot, two-story Translational Imaging Center is a joint effort between MPI Research, inviCRO, and 3D Imaging.

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Radiolabeling
Price on request
  • Radiolabeling of cellular therapeutics
  • Radiolabeling of antibodies, peptides, oligonucleotides, nanoparticles, and small molecules

  • Tracers for translational imaging

    • SPECT and PET for mouse
      • Large molecules: 124I, 125I, 123I,
        111In, 99mTc,18F
      • Small molecules: 125I, 123I, 18F, 11C
    • PET tracers for... Show more »
  • Radiolabeling of cellular therapeutics
  • Radiolabeling of antibodies, peptides, oligonucleotides, nanoparticles, and small molecules

  • Tracers for translational imaging

    • SPECT and PET for mouse
      • Large molecules: 124I, 125I, 123I,
        111In, 99mTc,18F
      • Small molecules: 125I, 123I, 18F, 11C
    • PET tracers for nonhuman and human primates
      • Large molecules: 124I, 89Zr, 11C, 18F
      • Small molecules: 124I, 11C, 18F
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Animal Bone Scanning
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Animal Imaging
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  • Small and large animal imaging modalities
  • All major in vivo imaging modalities
    • SPECT
    • PET
    • MRI
    • CT
    • DEXA
    • Fluoroscopy
    • X-ray
    • Laser Doppler
    • Ultrasonography
  • Complementary assays
    • Ex vivo biodistribution
    • Animal model development
    • Histology
  • Quantitative autoradiography... Show more »
  • Small and large animal imaging modalities
  • All major in vivo imaging modalities
    • SPECT
    • PET
    • MRI
    • CT
    • DEXA
    • Fluoroscopy
    • X-ray
    • Laser Doppler
    • Ultrasonography
  • Complementary assays
    • Ex vivo biodistribution
    • Animal model development
    • Histology
  • Quantitative autoradiography long- and short-lived radioisotopes
    • Two-dimensional, GLP-compliant
    • Three-dimensional
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Small Animal Autoradiography
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Histology and Pathology Services
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Custom Animal Models
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Laser Doppler Vibrometry
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Small Animal X-ray
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Small Animal DEXA/DXA Scanning
Animal Dual X-Ray Absorptiometry Scanning
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Tomography Services
Computed tomography services
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Magnetic resonance imaging image analysis
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Small Animal MRI
Small Animal Magnetic Resonance Imaging
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Single photon emission computed tomography image analysis
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Pharmaco-Imaging
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Regulatory Affairs Consulting
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• Regulatory support: current ANDAs, INDs, DMFs; clinical trials

• Regulatory support: current ANDAs, INDs, DMFs; clinical trials

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Clinical Ultrasonography
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Fluoroscopy
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Translational imaging data analysis
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MPI Research and our partners in the Translational Imaging Center provide analysis of imaging datasets in real time, allowing streamlined workflows with application-specific tools.

Key features include:

  • Powerful visualization of complex data and trends
  • Various threshold methods applied to individual, multi-modal, and... Show more »

MPI Research and our partners in the Translational Imaging Center provide analysis of imaging datasets in real time, allowing streamlined workflows with application-specific tools.

Key features include:

  • Powerful visualization of complex data and trends
  • Various threshold methods applied to individual, multi-modal, and dynamic datasets
  • Batch processing with customizable analysis routines for fast, quantitative assessments
  • Reliable quantification of distribution of radiopharmaceuticals, biologics, and small molecules in whole-body, organ, and sub-organ regions
  • Multi-disciplinary integration of in vitro/ ex vivo characterization and in vivo imaging for a better understanding of distribution, kinetics, and targeting
  • Kinetic modeling
  • Automated processes for organ segmentation
  • Availability of brain atlases for rodents and nonhuman primates
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Chemistry and Materials
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Clinical Laboratory Services
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Data Services
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Regulatory Affairs Services
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Image Analysis
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Radiography
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Animal Models and Studies
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Radiochemistry
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Clinical Imaging Services
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Computational Modeling
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Analytical Chemistry Services
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Animal Model in vivo Analyses
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Clinical Research
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Clinical and Anatomic Pathology
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Material Characterization Services
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Project Management, Consulting, & Support Services
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Animal Models of Disease
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Imaging & Spectroscopy
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