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Mouse Gene Modification Facility

Bronx, New York, US

The Albert Einstein College of Medicine Gene Modification Facility has over 25 years of experience in creating genetically engineered mice and has generated hundreds of gene targeted and transgenic mice as well as over 50 genetically modified mouse lines using CRISPR (clustered regularly interspaced short palindromic repeats) technology to advance biomedical research.
The facility offers a "start to finish" package encompassing the complete generation of genetically modified mouse lines by conventional homologous recombination based gene targeting strategies or by CRISPR-mediated gene targeting strategies. This service includes design and generation of targeting vectors and CRISPR reagents, pronuclear injections and the generation and genotyping of founder mice. Using CRISPR, genetically engineered mouse lines can be generated in as little as 2-4 months.
In addition, the facility has recently established... Show more »

The Albert Einstein College of Medicine Gene Modification Facility has over 25 years of experience in creating genetically engineered mice and has generated hundreds of gene targeted and transgenic mice as well as over 50 genetically modified mouse lines using CRISPR (clustered regularly interspaced short palindromic repeats) technology to advance biomedical research.
The facility offers a "start to finish" package encompassing the complete generation of genetically modified mouse lines by conventional homologous recombination based gene targeting strategies or by CRISPR-mediated gene targeting strategies. This service includes design and generation of targeting vectors and CRISPR reagents, pronuclear injections and the generation and genotyping of founder mice. Using CRISPR, genetically engineered mouse lines can be generated in as little as 2-4 months.
In addition, the facility has recently established TARGATT knock-in technology that allows "safe harbor" targeted transgenesis.

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Mouse Gene Modification Facility has not listed any services.

Transgenic Animal Model Development
Starting at $6,000.00 per animal

Crispr-Mediated Gene-Targeted Mouse Package

"Start to finish" package is the complete generation of genetically modified mouse lines by CRISPR-mediated gene targeting strategies.
-Includes design and generation of targeting vectors and CRISPR reagents
-Injections and the generation and genotyping of founder... Show more »

Crispr-Mediated Gene-Targeted Mouse Package

"Start to finish" package is the complete generation of genetically modified mouse lines by CRISPR-mediated gene targeting strategies.
-Includes design and generation of targeting vectors and CRISPR reagents
-Injections and the generation and genotyping of founder mice.

*Conventional Gene Knockouts*
*Knock-in Mutations*
*Mouse Lines Expressing Reporter Genes*
*Mouse Lines Expressing Tagged Proteins*

Using CRISPR, genetically engineered mouse lines can be generated in as little as 2-4 months.

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TARGATT Genome Editing
Price on request

The facility has recently established TARGATT knock-in technology that allows "safe harbor" targeted transgenesis. This technology can be utilized for a variety of applications including:

*Expression of Proteins with Pathogenic Mutations*
*Gene Knockdowns*
****Reporter Gene... Show more »

The facility has recently established TARGATT knock-in technology that allows "safe harbor" targeted transgenesis. This technology can be utilized for a variety of applications including:

*Expression of Proteins with Pathogenic Mutations*
*Gene Knockdowns*
*Reporter Gene Expression*
*Site-specific Cre-recombinase Expression for Advanced Conditional Knockout Models*

*"Start to Finish"* packages also available.

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Embryonic Stem Cell Generation
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Embryonic Stem Cell Screening
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ES Cell Targeting
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Blastocyst Injection
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Genotyping Services
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Mouse
Biology
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Cells and Tissues
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Mammalian Cell Culture
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Genetic Engineering
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Transgenic Mouse Services
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Biochemistry & Molecular Biology
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Nucleic Acid Services
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DNA Services
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