The T. C. Hsu Molecular Cytogenetics Facility (MCF) is funded by the Center for Genetics and Genomics (CGG). Dr. Guillermina Lozano is the Director and Dr. Asha S. Multani is the Co-Director of the facility. The MCF is administered through the Department of Genetics.
This facility offers Conventional as well as Molecular Cytogenetic services including cell line authentication, species identification, karyotyping, analysis of genomic instability, Fluorescence in Situ Hybridization (FISH) and Spectral Karyotyping.
One of the key expertise of our facility is to validate the origin of cell lines. Approximately 20-30% of all cell lines used in biomedical research are contaminated. Many top tier journals have begun to request proof of cell line authentication from investigators. Unlike other methods, chromosomal analysis is able to unambiguously identify cells from all common mammalian species and can also differentiate between cells from the same species. This analysis can therefore identify intra-species and inter-species cell line contaminations.
We will take the time to understand your project and plan for the preparation of samples for analysis. We will help with interpretation of the results and upon request provide a detailed description of method as well as microphotographs (color or black and white) suitable for inclusion in reports or manuscripts to the investigators.
The Molecular Cytogenetics Facility is equipped with:
High Impact Publications
Fluorescence in situ hybridization (FISH) on interphase and metaphase cells, paraffin sections, tissue microarray and frozen sections using whole chromosome paints, centromere probes, gene mapping with commercial and laboratory-generated DNA probes
Telomere studies including quantitation of telomeric DNA and Telomere Sister Chromatid Exchange analysis.
Molecular Cytogenetics Facility has not received any reviews.
Molecular Cytogenetics Facility has not received any endorsements.