Our mission at Mirimus is to push the boundaries of RNAi and engineer the most efficient RNAi tools for target identification, validation and toxicology assessment in vivo. Our goal is to build superior RNAi mouse models that can effectively mimic therapeutic suppression of targets and provide invaluable insight of the effects of target suppression both locally and systemically. Mirimus’ RNAi mouse models will become the key to the drug discovery process, empowering pharmaceutical companies with invaluable tools to perform in vivo target identification, validation and toxicity studies. They will provide researchers with powerful information and the ability to make key go no go decisions in order to maximize their therapeutic testing while obviating unnecessary expenses.
Mirimus employs an innovative Sensor Ping-Pong assay capable of deciphering elaborate shRNA libraries to identify the most potent shRNAs available. More than 25,000 shRNAs can be screened simultaneously for functionality and accurate prediction of their silencing capacity. Our inventory contains validated shRNAs for over 500 mouse genes. shRNAs can be custom made for any gene if not on our inventory.
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