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Minerva Imaging ApS

Copenhagen N, DK

Minerva Imaging is a scientifically driven CRO founded in 2011. Our focus is on the use of advanced oncology models and molecular imaging for translational cancer research and drug development.

We engage with our clients to understand their scientific questions and discuss how our methods and capabilities can provide answers.

Our competences build on more than two decades of research within oncology and molecular imaging performed at the University of Copenhagen and Rigshospitalet, the National University Hospital of Denmark.

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Radiolabeling
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Molecular Imaging
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Building on more than two decades of research in Nuclear Medicine we are proficient in conducting molecular imaging studies with a translational focus.
Imaging studies can be combined with our advanced oncology models to investigate the in vivo biodistribution, e.g. radiolabeled antibodies, or imaging biomarkers in drug efficacy... Show more »

Building on more than two decades of research in Nuclear Medicine we are proficient in conducting molecular imaging studies with a translational focus.
Imaging studies can be combined with our advanced oncology models to investigate the in vivo biodistribution, e.g. radiolabeled antibodies, or imaging biomarkers in drug efficacy studies.

We facilitate clinical translation (Phase I/II) of radio-tracers in collaboration with our clinical partners.

Capabilities:

Available radiotracers:

18F-FDG, 18F-FLT, 18F-FET, 18F-NaF, 18F-FES
68Ga-PSMA, 68Ga-RGD
64Cu-DOTATATE
89Zr labeled antibodies, e.g. 89Zr-trastuzumab
Custom radiolabeling of small molecules, peptides, proteins and antibodies using e.g. 89Zr.

Imaging modalities:

PET/CT imaging
SPECT/CT imaging
MR imaging
Optical (bioluminescence) imaging

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Drug Development
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We have extensive experience in design and execution of pre-clinical studies for drug development within oncology and immuno-oncology. We can perform studies with cell line based models as well as PDX models available through the START-MINERVA collaboration. Studies can be designed to take advantage of our capabilities of... Show more »

We have extensive experience in design and execution of pre-clinical studies for drug development within oncology and immuno-oncology. We can perform studies with cell line based models as well as PDX models available through the START-MINERVA collaboration. Studies can be designed to take advantage of our capabilities of orthotopic and metastatic models, external radiation therapy, and advanced non-invasive imaging.

Our capabilities

  • Subcutaneous xenograft models (rats and mice)
  • Targeted radionuclide therapy
  • Orthotopic xenograft models
  • PET/CT imaging
  • Subcutaneous and orthotopic syngeneic models
  • SPECT/CT imaging
  • PDX models, including orthotopic implantation
  • MR imaging
  • External radiation therapy
  • Optical (bioluminescence) imaging
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Cardiovascular Animal Models
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We have a strong focus on imaging of pathophysiology in cardiovascular disease. Using relevant animals models of cardiovascular disease and longitudinal study designs we can follow therapeutic interventions by non-invasive imaging. Studies can be designed to take advantage of in-depth capabilities of microsurgery to establish e.g.... Show more »

We have a strong focus on imaging of pathophysiology in cardiovascular disease. Using relevant animals models of cardiovascular disease and longitudinal study designs we can follow therapeutic interventions by non-invasive imaging. Studies can be designed to take advantage of in-depth capabilities of microsurgery to establish e.g. myocardial infarction and ischemia-reperfusion models in rodents and larger species. Also, we have a long track record of using PET/CT imaging to monitor vascular inflammation in atherosclerosis.

Capabilities:

  • Myocardial infarction models
  • Ischemia-reperfusion models
  • Atherosclerosis models
  • Perfusion imaging PET/CT, SPECT/CT and MRI
  • Cardiac function, ejection fraction by MRI and SPECT/CT
  • Imaging of vascular inflammation by PET/CT
  • Ex vivo quantification of disease
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Myocardial Infarction Animal Models
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Atherosclerosis Animal Models
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Myocardial Ischemia Reperfusion Injury Animal Models
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Tomography Services
Computed tomography services
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Small Animal Bioluminescence Imaging
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Small Animal MRI
Small Animal Magnetic Resonance Imaging
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Small Animal SPECT Scan
Small Animal Single Photon Emission Computed Tomography Scan
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Syngeneic (Allograft) Tumor Models
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Small Animal PET Scan
Small Animal Positron Emission Tomography Scan
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Orthotopic Tumor Animal Models
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Xenograft Models
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Mouse
Rat
Oncology Animal Models
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Oncology Animal Models Services

Oncology Animal Models Services

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Animal Models of Disease
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Animal Models of Disease Services

Animal Models of Disease Services

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Animal Models and Studies
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Animal Models and Studies Services

Animal Models and Studies Services

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Drug Discovery & Development
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Drug Discovery & Development Services

Drug Discovery & Development Services

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Animal Imaging
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Animal Imaging Services

Animal Imaging Services

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Animal Model in vivo Analyses
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Animal Model in vivo Analyses Services

Animal Model in vivo Analyses Services

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Patient Derived Xenograft (PDX)
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Patient Derived Xenograft (PDX) Services

Patient Derived Xenograft (PDX) Services

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Nuclear imaging
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Nuclear imaging Services

Nuclear imaging Services

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Radiography
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Radiography Services

Radiography Services

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Imaging & Spectroscopy
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Imaging & Spectroscopy Services

Imaging & Spectroscopy Services

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Preclinical Targeted Radionuclide Therapy
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We have substantial experience in performing studies with targeted radionuclide therapy in oncology. Our capabilities include testing of alpha- as well as beta-emitting ligands in subcutaneous, orthotropic or metastatic cancer models.

We facilitate clinical translation into Phase I studies including clinical trial design and... Show more »

We have substantial experience in performing studies with targeted radionuclide therapy in oncology. Our capabilities include testing of alpha- as well as beta-emitting ligands in subcutaneous, orthotropic or metastatic cancer models.

We facilitate clinical translation into Phase I studies including clinical trial design and execution in collaboration with our clinical partners.

Capabilities:

  • Approval of handling alpha- and beta-emitters, e.g. 177Lu, 131I, 227Th
  • Targeted radionuclide therapy in subcutaneous and orthotopic PDX models
  • Targeted radionuclide therapy in metastatic models
  • Custom radiolabeling of small molecules, peptides, proteins and antibodies
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Chemistry and Materials
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Chemistry and Materials Services

Chemistry and Materials Services

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Radiochemistry
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Radiochemistry Services

Radiochemistry Services

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