For applications including proteomics, drug discovery, immunogenicity, and food analysis, state-of-the-art Surface Plasmon Resonance (SPR) technology allows for label-free, real-time biomolecular interaction analysis. Using purified preparations or complex mixtures, binding interactions between proteins, lipids, carbohydrates, nucleic acids, small molecules, and cells/viruses can be examined quantitatively in their native state with low sample consumption. In a typical experiment, the ligand (‘bait’) is immobilized to a gold-plated sensor chip and repeated injections of analyte (binding partner ‘target’) are then flowed overtop. Instrumentation: Biacore 3000.
Complementary mass spectrometry and multiplexing services are also available - please inquire.
McGill: $75 per hour + sensor chip costs
External Academic: $90 per hour + sensor chip costs
Commercial: $125 per hour + sensor chip costs
"McGill SPR did an excellent work for my first project one year ago. This is my second project. I am very happy with the service and plan to go with McGill SPR for another project soon. Mark is very professional and very friendly. Technically, I am particularly impressed that he has managed to successfully work with proteins that contain substantial levels of SRP-unfriendly stuffs."
"Mark has provided excellent service. He has excellent trouble-shooting capability. He has tried his best to obtain good results. He is friendly and easy to work with. I would come back with more projects."
McGill SPR Facility has not received any endorsements.