Macrogen, a leading company in precision medicine and biotechnology, was established on June 5, 1997 based on the Genomic Medicine Institute of the Seoul National University College of Medicine. In February 2000, Macrogen became the first ever bio venture in Korea to be listed on the KOSDAQ. Since then, Macrogen has continued to be actively engaged in R&D fields of genetic and genomic analyses. Today, Macrogen has become a global expert in genomic analysis and a leader in Korean biotechnology, working closely with over 18,000 research clients across 153 countries worldwide. In addition to providing services to clients all over the world, Macrogen contributes to the advancement of bioindustries through a wide range of R&D and CSR activities.
Capillary Electrophoresis Sequencing (CES) is a service that analyzes DNA sequences using biochemical methods. Macrogen's CES service maximizes customer satisfaction through a variety of service lineups ranging from standard sequencing, which is the most popular service, to Identification service, Fragment analysis service, and customized sequencing service, We are doing. In addition, it is used for various research purposes in a wide range of fields such as basic research on molecular biology, breeding research, genetic disease research, paternity confirmation, and forensic research, and it has become a mainstay for development of biotechnology industry.
Macrogen's CES service provides additional custom services (gDNA extraction, primer synthesis, PCR amplification and purification) as well as general sequencing services as well as various customer requests. In addition, we can request the desired service through a separate online ordering system for customer convenience. We will monitor the entire process for each order sample and follow up the final result.
Macrogen offers a wide range of oligosynthesis services through high quality raw materials and optimized processes. Synthesized oligos are widely used in biological and medical fields such as DNA sequencing, PCR, SNP research, Gene Synthesis, NGS service, qPCR service, Biochip, and siRNA expression.
Macrogen uses 1000 Å CPG to provide high quality oligo, and MOPC Tablets developed independently are offered free of charge as standard for all oligos. MOPC purification is similar to HPLC and PAGE purification with cartridge purification. In addition, for thorough quality control, we use MALDI-TOF to perform QC of all the oligos and synthesized oligos are provided with the result report.
Macrogen's Oligo service is performed by automation equipment from synthesis to refining and dispensing. This enables more precise dispensing and provides customers with convenient conditions based on standardized services. In addition, you can monitor them through the online ordering system (LIMS), which is built in-house with respect to the entire process, from online ordering, up-and-downs synthesis.
Gene Synthesis service is a service that synthesizes the genes according to the order of the customer's gene sequence and is widely used in the field of researching recombinant DNA such as vaccine production, gene therapy and transcription expression.
Macrogen's Gene Synthesis service provides not only DNA sequencing but also free cloning services to provide plasmid DNA-based gene synthesis services, and mutagenesis services enable a broader range of synthesis services. We also guarantee 100% base sequence based on ABI 3730xl sequencing equipment, and you can inquire orders and quotations conveniently through LIMS (Laboratory Information Management System).
Macrogen provides services to produce and supply genetically modified mice (GEM) through experimental mice that are very similar to humans. GEM, also called genetically modified mouse, refers to mice that have been genetically engineered to insert, remove, and modify specific genes. It is widely used in biomedical and medical research fields to discover the function of human genes and is an essential preliminary experimental resource for the development of new drugs.
Macrogen's GEM service is divided into Transgenic Mouse, Knock-Out / Knock-In Mouse, and additional services that provide additional services. Transgenic Mouse is a transgenic mouse for studying gene function by inserting a specific gene. Knock-Out Mouse is a transgenic mouse that suppresses the expression of target genes by removing specific genes. Knock-In Mouse is a genetically modified mouse that can regulate and detect the expression of a target gene by modifying a specific gene. In addition, we provide EZ-KO Mouse service from ES cell purchase to KO mouse production and additional services such as microinjection, embryo freezing and mouse restoration, all genetically modified mouse breeding and screening.
Macrogen's GEM service is produced through sufficient experiment design for efficient production process. We also provide customized partial process services to meet customers' diverse needs and maintain a strict quarantine system to keep all mice in SPF status.
Macrogen uses a precise DNA microarray technology to provide various gene analysis services. Microarrays are called various terms such as DNA chip, Biochip, gene-array, etc. Invisible microscopic probes are arranged on a chip and reacted with DNA, RNA, protein, etc. to measure gene expression patterns. This is a technology you can check. For microarray analysis, it is essential to have accurate microarray data and to accurately identify genetic information from the results of experiments.
We have the products of Illumina, Affymetrix and Agilent, which are the only major suppliers of Microarray products in Korea. Based on these equipments, we provide gene analysis services for various research purposes such as mRNA, miRNA, SNP, CGH and DNA methylation Is provided. Macrogen is committed to delivering high-quality data at all times, based on a number of experimental and analytical experiences with researchers worldwide.
NGS (Next Generation Sequencing) technology, called Next Generation Sequencing, is an analysis method that divides the genome as a collection of all genes into numerous pieces and then assembles the obtained sequence to obtain the entire genome sequence. Since the technology has been commercialized since the 2000s, as the technology has developed so rapidly, a large amount of genome information has been obtained within a short period of time and it can be utilized in various research fields. In particular, as the cost and time of genome analysis are gradually declining, demand for genome analysis of various organisms including humans is rapidly increasing. Recently, NGS-based clinical research centering on the medical field has been actively developed, and many studies have been conducted to identify gene mutation through the technology and to discover the function of a new gene. This will accelerate the realization of precision medicine which can provide individualized treatment based on individual genome information.
Macrogen manufactures a large amount of genome data every year through a variety of equipment. It also provides faster and more accurate genome analysis services at an economical cost to help researchers research and provide diagnostic services to the general public. We also provide genomic analysis services based on various research purposes such as Whole Genome, Exome, Transcriptome, Epigenome, and Metagenome and Bioinformatics results based on these data. Based on its long experience and know-how, Macrogen is leading the field of precision medicine using NGS technology by presenting Total Genomic Solution to researchers all over the world.
Macrogen Korea has not received any endorsements.