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Luceome Biotechnologies

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Tucson, Arizona, US

About Luceome Biotechnologies

Luceome Biotechnologies is an emerging, privately-held biotechnology company located in Tucson, Arizona. Luceome enables drug discovery by leveraging its assay technology for identification of drugs against kinases.

Luceome provides unique assay solutions (KinaseSeeker™ and KinaseLite™) to clients for meeting their selectivity profiling needs as well as for the development of assays against specific targets. Luceome’s assays are based on a technology platform that utilizes luciferase fragment complementation. The resulting luminescence detection is sensitive with low background interference, allowing identification of target and off-target effects of drug candidates.

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Small business Woman owned small business

Our Services (25)

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High Throughput Screening (HTS)

Price on request

Available Screening Options:

  • Inhibition at single inhibitor dose
  • Dose Response Titrations – IC50 Determinations
  • Compound Library Screening
  • Custom Assay Development

Available Kinase Panels:

  • Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
  • Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
  • Mixed Panel (50 select kinases distributed across kinome)
  • Complete Panel of 363 kinases
  • A la carte: Pick kinases of your choice and build your own panel

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Kinase Assays

Price on request

Available Screening Options:

  • Inhibition at single inhibitor dose
  • Dose Response Titrations – IC50 Determinations
  • Compound Library Screening
  • Custom Assay Development

Available Kinase Panels:

  • Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
  • Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
  • Mixed Panel (50 select kinases distributed across kinome)
  • Complete Panel of 363 kinases
  • A la carte: Pick kinases of your choice and build your own panel

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Kinase Target Specific Assays

Price on request

Available Screening Options:

  • Inhibition at single inhibitor dose
  • Dose Response Titrations – IC50 Determinations
  • Compound Library Screening
  • Custom Assay Development

Available Kinase Panels:

  • Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
  • Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
  • Mixed Panel (50 select kinases distributed across kinome)
  • Complete Panel of 363 kinases
  • A la carte: Pick kinases of your choice and build your own panel

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Kinase Assay Development

Price on request

Luceome provides a custom kinase assay development service to clients who wish to use the luciferase fragment complementation assay for screening inhibitors in-house.  We will tailor the assay to fit your profiling needs.  Contact us for an initial Feasibility Assessment.

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Compound Profiling

Price on request

Compound Profiling Against Kinases

Available Screening Options:

  • Inhibition at single inhibitor dose
  • Dose Response Titrations – IC50 Determinations
  • Compound Library Screening
  • Custom Assay Development

Available Kinase Panels:

  • Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
  • Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
  • Mixed Panel (50 select kinases distributed across kinome)
  • Complete Panel of 363 kinases
  • A la carte: Pick kinases of your choice and build your own panel

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Tyrosine Kinase Assay

Price on request

Available Screening Options:

  • Inhibition at single inhibitor dose
  • Dose Response Titrations – IC50 Determinations
  • Compound Library Screening
  • Custom Assay Development

Available Kinase Panels:

  • Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
  • A la carte: Pick kinases of your choice and build your own panel

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BTK Assay Services

Price on request

Features and Benefits

  • Binding Assay:  Identify active site directed as well as allosteric inhibitors
  • Luminescence detection:  Low false positives from fluorescent compounds
  • Cell-free Format:  Identify lead compounds in a complex cellular environment at cellular ATP concentrations
  • Homogeneous:  Portable; Adaptable to high-throughput
  • Sensitive:  Low Background; Broad dynamic range
  • Economical:  Contact us to learn about pricing
  • Rapid turnaround of data: 7-10 business days

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Anaplastic Lymphoma Kinase (ALK) Assays

Price on request

Features and Benefits

  • Binding Assay:  Identify active site directed as well as allosteric inhibitors
  • Luminescence detection:  Low false positives from fluorescent compounds
  • Cell-free Format:  Identify lead compounds in a complex cellular environment at cellular ATP concentrations
  • Homogeneous:  Portable; Adaptable to high-throughput
  • Sensitive:  Low Background; Broad dynamic range
  • Economical:  Contact us to learn about pricing
  • Rapid turnaround of data: 7-10 business days

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VEGF Signaling Assays

Vascular Endothelial Growth Factor Assays
Price on request

Features and Benefits

  • Binding Assay:  Identify active site directed as well as allosteric inhibitors
  • Luminescence detection:  Low false positives from fluorescent compounds
  • Cell-free Format:  Identify lead compounds in a complex cellular environment at cellular ATP concentrations
  • Homogeneous:  Portable; Adaptable to high-throughput
  • Sensitive:  Low Background; Broad dynamic range
  • Economical:  Contact us to learn about pricing
  • Rapid turnaround of data: 7-10 business days

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Protein Kinase B (Akt) Assays

Price on request

Features and Benefits

  • Binding Assay:  Identify active site directed as well as allosteric inhibitors
  • Luminescence detection:  Low false positives from fluorescent compounds
  • Cell-free Format:  Identify lead compounds in a complex cellular environment at cellular ATP concentrations
  • Homogeneous:  Portable; Adaptable to high-throughput
  • Sensitive:  Low Background; Broad dynamic range
  • Economical:  Contact us to learn about pricing
  • Rapid turnaround of data: 7-10 business days

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Human Epidermal Growth Factor Receptor (HER/EGFR) Assays

Price on request

Features and Benefits

  • Binding Assay:  Identify active site directed as well as allosteric inhibitors
  • Luminescence detection:  Low false positives from fluorescent compounds
  • Cell-free Format:  Identify lead compounds in a complex cellular environment at cellular ATP concentrations
  • Homogeneous:  Portable; Adaptable to high-throughput
  • Sensitive:  Low Background; Broad dynamic range
  • Economical:  Contact us to learn about pricing
  • Rapid turnaround of data: 7-10 business days

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Checkpoint Kinase-1 (ChK-1) Assays

Price on request

Features and Benefits

  • Binding Assay:  Identify active site directed as well as allosteric inhibitors
  • Luminescence detection:  Low false positives from fluorescent compounds
  • Cell-free Format:  Identify lead compounds in a complex cellular environment at cellular ATP concentrations
  • Homogeneous:  Portable; Adaptable to high-throughput
  • Sensitive:  Low Background; Broad dynamic range
  • Economical:  Contact us to learn about pricing
  • Rapid turnaround of data: 7-10 business days

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Colony Stimulating Factor 1 Receptor (CSF-1R) Assays

Price on request

Features and Benefits

  • Binding Assay:  Identify active site directed as well as allosteric inhibitors
  • Luminescence detection:  Low false positives from fluorescent compounds
  • Cell-free Format:  Identify lead compounds in a complex cellular environment at cellular ATP concentrations
  • Homogeneous:  Portable; Adaptable to high-throughput
  • Sensitive:  Low Background; Broad dynamic range
  • Economical:  Contact us to learn about pricing
  • Rapid turnaround of data: 7-10 business days

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Kinase Screening and Profiling

Price on request

Available Screening Options:

  • Inhibition at single inhibitor dose
  • Dose Response Titrations – IC50 Determinations
  • Compound Library Screening
  • Custom Assay Development

Available Kinase Panels:

  • Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
  • Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
  • Mixed Panel (50 select kinases distributed across kinome)
  • Complete Panel of 363 kinases
  • A la carte: Pick kinases of your choice and build your own panel

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Biochemical Assays

Price on request
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Cell Signaling Analyses

Price on request
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Drug Discovery

Price on request
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Receptor Assays

Price on request
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Hit Identification

Price on request
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Enzyme Assays

Price on request
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Drug Discovery & Development

Price on request
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Cell-Based Assays

Price on request
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Biology

Price on request
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Biochemistry & Molecular Biology

Price on request
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Lead Identification and Validation

Price on request
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