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High Throughput Screening (HTS)
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type... Show more »
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
- Mixed Panel (50 select kinases distributed across kinome)
- Complete Panel of 363 kinases
- A la carte: Pick kinases of your choice and build your own panel
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type... Show more »
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
- Mixed Panel (50 select kinases distributed across kinome)
- Complete Panel of 363 kinases
- A la carte: Pick kinases of your choice and build your own panel
Kinase Target Specific Assays
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type... Show more »
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
- Mixed Panel (50 select kinases distributed across kinome)
- Complete Panel of 363 kinases
- A la carte: Pick kinases of your choice and build your own panel
Luceome provides a custom kinase assay development service to clients who wish to use the luciferase fragment complementation assay for screening inhibitors in-house. We will tailor the assay to fit your profiling needs. Contact us for an initial Feasibility Assessment.
Luceome provides a custom kinase assay development service to clients who wish to use the luciferase fragment complementation assay for screening inhibitors in-house. We will tailor the assay to fit your profiling needs. Contact us for an initial Feasibility Assessment.
Compound Profiling Against Kinases
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across... Show more »
Compound Profiling Against Kinases
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
- Mixed Panel (50 select kinases distributed across kinome)
- Complete Panel of 363 kinases
- A la carte: Pick kinases of your choice and build your own panel
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
- A la carte: Pick kinases of your choice and build your own panel
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
- A la carte: Pick kinases of your choice and build your own panel
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to... Show more »
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to high-throughput
- Sensitive: Low Background; Broad dynamic range
- Economical: Contact us to learn about pricing
- Rapid turnaround of data: 7-10 business days
Anaplastic Lymphoma Kinase (ALK) Assays
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to... Show more »
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to high-throughput
- Sensitive: Low Background; Broad dynamic range
- Economical: Contact us to learn about pricing
- Rapid turnaround of data: 7-10 business days
VEGF Signaling Assays
Vascular Endothelial Growth Factor Assays
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to... Show more »
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to high-throughput
- Sensitive: Low Background; Broad dynamic range
- Economical: Contact us to learn about pricing
- Rapid turnaround of data: 7-10 business days
Protein Kinase B (Akt) Assays
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to... Show more »
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to high-throughput
- Sensitive: Low Background; Broad dynamic range
- Economical: Contact us to learn about pricing
- Rapid turnaround of data: 7-10 business days
Human Epidermal Growth Factor Receptor (HER/EGFR) Assays
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to... Show more »
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to high-throughput
- Sensitive: Low Background; Broad dynamic range
- Economical: Contact us to learn about pricing
- Rapid turnaround of data: 7-10 business days
Checkpoint Kinase-1 (ChK-1) Assays
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to... Show more »
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to high-throughput
- Sensitive: Low Background; Broad dynamic range
- Economical: Contact us to learn about pricing
- Rapid turnaround of data: 7-10 business days
Colony Stimulating Factor 1 Receptor (CSF-1R) Assays
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to... Show more »
Features and Benefits
- Binding Assay: Identify active site directed as well as allosteric inhibitors
- Luminescence detection: Low false positives from fluorescent compounds
- Cell-free Format: Identify lead compounds in a complex cellular environment at cellular ATP concentrations
- Homogeneous: Portable; Adaptable to high-throughput
- Sensitive: Low Background; Broad dynamic range
- Economical: Contact us to learn about pricing
- Rapid turnaround of data: 7-10 business days
Kinase Screening and Profiling
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type... Show more »
Available Screening Options:
- Inhibition at single inhibitor dose
- Dose Response Titrations – IC50 Determinations
- Compound Library Screening
- Custom Assay Development
Available Kinase Panels:
- Full-Length Kinase Panel (95 wild-type full length kinases distributed across kinome)
- Tyrosine Kinase Panel (119 wild-type kinase-domain and full-length tyrosine kinases)
- Mixed Panel (50 select kinases distributed across kinome)
- Complete Panel of 363 kinases
- A la carte: Pick kinases of your choice and build your own panel
Request a quote for more information about this service.
Request a quote for more information about this service.
Request a quote for more information about this service.
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Lead Identification and Validation
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Drug Discovery & Development
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Biochemistry & Molecular Biology
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