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Likarda, LLC

Kansas City, Kansas, US

Likarda, LLC is an exciting biotech company bringing to market disruptive technologies that improve healthcare outcomes and lower costs for pets and people alike. Likarda utilizes a proprietary cell culture system to create three-dimensional cell clusters, or miniaturized organs, having applications in markets from drug discovery and development to cell-based transplantation and regenerative medicine. For instance, pharmaceutical companies can test new drug compounds on our human 3D cell clusters, providing a better prediction of how the drugs will work in the body.

Likarda’s founders developed its innovations while employed as researchers at the University of Kansas Medical Center where they were focused on discovering and providing next generation treatments for diabetes. The technology consists of a proprietary and patented micromold plate and manufacturing process.

In 2012, the founders discovered the power... Show more »

Likarda, LLC is an exciting biotech company bringing to market disruptive technologies that improve healthcare outcomes and lower costs for pets and people alike. Likarda utilizes a proprietary cell culture system to create three-dimensional cell clusters, or miniaturized organs, having applications in markets from drug discovery and development to cell-based transplantation and regenerative medicine. For instance, pharmaceutical companies can test new drug compounds on our human 3D cell clusters, providing a better prediction of how the drugs will work in the body.

Likarda’s founders developed its innovations while employed as researchers at the University of Kansas Medical Center where they were focused on discovering and providing next generation treatments for diabetes. The technology consists of a proprietary and patented micromold plate and manufacturing process.

In 2012, the founders discovered the power of the Kanslets for secondary drug testing and have multiple publications in support of the technology. Shortly after making this discovery, Likarda was established and the intellectual property and patents were exclusively licensed from the University of Kansas.

Likarda partners with its clients to champion high quality, cutting-edge products and services, constantly seeking to create the next improved version. To accomplish this we have well-defined long-range goals, with the added opportunity for flexibility and growth.

Founded in 2012

Publications

  • Amin J, Ramachandran K, Williams SJ, Lee A, Novikova L, Stehno-Bittel L. A simple, reliable method for high-throughput screening for diabetes drugs using 3D β-cell spheroids. J Pharmacol Toxicol Methods. 2016 Aug 20;82:83-89. doi: 10.1016/j.vascn.2016.08.005.
  • Ramachandran K, Peng X, Bokvist K, Stehno-Bittel L. Assessment of re-aggregated human pancreatic islets for secondary drug screening. Br J Pharmacol. 2014 Jun;171(12):3010-22. doi: 10.1111/bph.12622.
  • Ramachandran K, Williams SJ, Huang HH, Novikova L, Stehno-Bittel L. Engineering islets for improved performance by optimized reaggregation in a micromold. Tissue Eng Part A. 2013 Mar;19(5-6):604-12. doi: 10.1089/ten.TEA.2012.0553.
  • Cole C, Burgoyne T, Lee A, Stehno-Bittel L, Zaid G. Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice. BMC Complement Altern Med. 2015 Aug 5;15:264. doi: 10.1186/s12906-015-0774-5.
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Real-Time Cytotoxicity Assay
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Request a quote for more information about this service.
BioTek Cytation 5
3D Cell-Based Assays
Price on request

Likarda produces 3D cell-based clusters and assays using a uniform 3D, scaffold-free methodology. Our clusters are all uniform in size, and run on 96 or 384-well plate formats. We're able to produce them from a variety of different cell types in many different species whether primary or cell lines. We've worked in both... Show more »

Likarda produces 3D cell-based clusters and assays using a uniform 3D, scaffold-free methodology. Our clusters are all uniform in size, and run on 96 or 384-well plate formats. We're able to produce them from a variety of different cell types in many different species whether primary or cell lines. We've worked in both human and animal health. These assays can be useful for toxicology, metabolism, cell health and a number of other aspects.

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Human
Mouse
Rat
Dog
Cancer
Cat
Diabetes Type 1
Diabetes Type 2
pancreatic
Cell culture
Drug discovery
in vitro toxicity
heptotoxicity
scaffold-free 3D culture
primary cell culture
Cytotoxicity
Diabetes
Cell-based assays
immortalized cell culture
3D culture
Drug Safety and Toxicology
Cell-Based Assays
Price on request

In addition to the 3D cell-based assays that we conduct, we're able to complete tests in 2D on monolayer or suspension cell cultures. We design experiments to match the scientific question posed by the client. We've worked with primary cells, cell lines, xenografts models, and a variety of species including humans, dogs,... Show more »

In addition to the 3D cell-based assays that we conduct, we're able to complete tests in 2D on monolayer or suspension cell cultures. We design experiments to match the scientific question posed by the client. We've worked with primary cells, cell lines, xenografts models, and a variety of species including humans, dogs, cat, mouse, and rats. In addition, our scientists are experienced in developing novel assays for clients, and have published new methods for multiplexing and in vitro toxicity assays.

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Mettler Toledo Analytical Balance AG104
Mettler Toledo pH Meter MP225
Nikon Inverted Microscope Eclipse TE200
Zeiss Microscope III RS
Olympus UPlanAPO wet and dry objectives
Cancer
Immunotherapy
Immunoassays
Obesity & Diabetes
Analytical HPLC
Fluorescent labeling
Liver
Cell culture
Drug discovery
in vitro toxicity
heptotoxicity
ELISA
Immunofluorescence
scaffold-free 3D culture
primary cell culture
immunohistochemistry
histology
microscopy
Agilent 1100
Ames test
Cytotoxicity
Diabetes
toxicology
drug metabolism
Immunooncology
Biomarker analysis
Cell-based assays
BioTek Cytation 5
live-cell imaging
metabolism
Liver Function
Perkin Elmer Enspire
alphaLISA
luminescence
cell imaging
Chemiluminescent Immunoassay
drug toxicity
calcium imaging
Drug Safety and Toxicology
comparison testing
Method Development
Method Validation
Stability Studies
Thyroid disease
drug delivery
drug effects
Custom Assays
Project management
efficacy testing
Drug-drug interaction
Toxicity
drug resistance
GMP Material Storage
NanoEnTek EVE automated cell counter
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Thermo Scientific Steri-Cycle Direct Heat C02 Incubators
Assay Development
Price on request

New therapies that utilize the intact immune system, alter genes, or are comprised of cells as therapy, require complex in vitro assays. Likarda's scientists are experienced in developing and validating new assays, depending on the client's needs. Publications by our scientists, Drs. Linsdey Ott and Karthik Rakmachandran highlight some of the capabilities of the team.

New therapies that utilize the intact immune system, alter genes, or are comprised of cells as therapy, require complex in vitro assays. Likarda's scientists are experienced in developing and validating new assays, depending on the client's needs. Publications by our scientists, Drs. Linsdey Ott and Karthik Rakmachandran highlight some of the capabilities of the team.

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Eppendorf Centrifuge 5415C
Mettler Toledo Analytical Balance AG104
Mettler Toledo pH Meter MP230
Nikon Inverted Microscope Eclipse TE200
Cancer
Analytical HPLC
Cardiovascular
Activity
multiplex
Liver
Skeletal
Cell culture
Biology
Drug discovery
assay development
ELISA
Agilent 1100
Diabetes
Autoimmune
Respiratory Diseases
Cell-based assays
BioTek Cytation 5
3D culture
Perkin Elmer Enspire
alphaLISA
cell imaging
cardiotoxicity
Amino Acid Analysis
Ames
Drug Safety and Toxicology
assay optimization
Method Development
Method Validation
Stability Studies
Thyroid disease
kidney
affinity chromatography
kinetics
dose response
High-throughput data analysis
inhibition assessment
GMP Material Storage
NanoEnTek EVE automated cell counter
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Thermo Scientific Steri-Cycle Direct Heat C02 Incubators
Zeiss AxioVert Epifluorescence Microscope
Caron Environmental Test Chamber
Caron Photostability Test Chamber
Cell-Based Compound Screening
Price on request

Likarda's scientific team conducts large- and small-scale compound screens for academia, small start-ups, or large pharmaceutical companies. We utilize liquid handling robots and our patented microplates to conduct high through-put screens in 2D or with 3D cell clusters.

We have extensive experience in searching for... Show more »

Likarda's scientific team conducts large- and small-scale compound screens for academia, small start-ups, or large pharmaceutical companies. We utilize liquid handling robots and our patented microplates to conduct high through-put screens in 2D or with 3D cell clusters.

We have extensive experience in searching for synergies or antagonistic relationships between test compounds and a variety of molecules including marketed drugs, environmental factors, or other test compounds. Our proprietary computer programs direct our robotics lab to test 1000s of compound combinations in a rapid time frame, with almost instantaneous results.

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Branson Sonifier 250
Nikon Inverted Microscope Eclipse TE200
Thermo Forma -80 Freezer 8560
Thermo Savant DNA 120 Speed Vac DNA 120-115
Cancer
multiplex
neurological
Renal
Cell culture
Drug discovery
ELISA
scaffold-free 3D culture
primary cell culture
Agilent 1100
Diabetes
Respiratory Diseases
Cell-based assays
immortalized cell culture
metabolomics
GMP
BioTek Cytation 5
3D culture
Perkin Elmer Enspire
alphaLISA
stability
luminescence
cell imaging
Chemiluminescent Immunoassay
cardiotoxicity
Drug Safety and Toxicology
proliferation
Method Development
Method Validation
Colorimetric
Immunochemistry
Thyroid disease
High-throughput data analysis
GMP Material Storage
NanoEnTek EVE automated cell counter
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Zeiss AxioVert Epifluorescence Microscope
Liver Disease
Fisher Isotemp Chromatography Refrigerator
Rotovap Evaporating System
drug-drug interactions
Cell Viability Assays
Price on request

Cell viability assays are essential for a variety of research questions. We routinely use colorimetric, luminescent and fluorescent detectors of cell viability. For certain scientific goals, cell function may be a better representation of cell viability. We use standard assays or develop novel cell viability tests, depending on the need.

Cell viability assays are essential for a variety of research questions. We routinely use colorimetric, luminescent and fluorescent detectors of cell viability. For certain scientific goals, cell function may be a better representation of cell viability. We use standard assays or develop novel cell viability tests, depending on the need.

« Show less
Nikon Inverted Microscope Eclipse TE200
Thermo Forma -80 Freezer 8560
Cancer
Cardiovascular
neurological
Skeletal
Renal
pancreatic
Drug discovery
in vitro toxicity
heptotoxicity
Immunofluorescence
immunohistochemistry
microscopy
Cytotoxicity
Diabetes
neurodegenerative diseases
Cell-based assays
BioTek Cytation 5
live-cell imaging
Gastroenterology
Perkin Elmer Enspire
Cybio integrated multi device robotics
Drug Safety and Toxicology
activity testing
Thyroid disease
Bone disease
Time Resolved Fluorescence
GMP Material Storage
NanoEnTek EVE automated cell counter
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Zeiss AxioVert Epifluorescence Microscope
Liver Disease
Agilent HPLC 1100
Cytotoxicity Assays
Price on request

We utilize a number of cell toxicity assays using standard tests based on fluorescent, luminescent or colorimetric read-outs. Alternatively, we have designed unique multiplexed assays that measured cell toxicity, biomarkers, and cellular metabolic outcomes. These custom assays provide our clients with robust results at a lower... Show more »

We utilize a number of cell toxicity assays using standard tests based on fluorescent, luminescent or colorimetric read-outs. Alternatively, we have designed unique multiplexed assays that measured cell toxicity, biomarkers, and cellular metabolic outcomes. These custom assays provide our clients with robust results at a lower cost and with less test compound and less time. Drs. Lindsey Ott and Karthik Rakmachandran have published manuscripts on some of our novel assays.

Toxicity from drug-drug interactions is important information to obtain early in the drug development process. Likarda has proprietary programming that allows our liquid handling instruments to test for drug-drug interactions in a high-throughput manner, and (if needed) in 3D cell culture.

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Mettler Toledo Analytical Balance AG104
Mettler Toledo pH Meter MP230
Nikon Inverted Microscope Eclipse TE200
Thermo Scientific Upright Freezer ULT2540-3-A41
Cancer
Fluorescent labeling
Renal
pancreatic
Drug discovery
in vitro toxicity
heptotoxicity
ELISA
scaffold-free 3D culture
neuroscience
microscopy
Cytotoxicity
Diabetes
neurodegenerative diseases
Cell-based assays
GMP
BioTek Cytation 5
live-cell imaging
3D culture
Gastroenterology
Perkin Elmer Enspire
alphaLISA
luminescence
Drug Safety and Toxicology
Method Development
Method Validation
Thyroid disease
Fluorescence
Time Resolved Fluorescence
NanoEnTek EVE automated cell counter
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Zeiss AxioVert Epifluorescence Microscope
Liver Disease
Fisher Isotemp Chromatography Refrigerator
drug-drug interactions
Agilent HPLC 1100
hepatotoxicity
Cell Death Assays
Price on request

We utilize a number of cell death assays using standard tests based on fluorescent, luminescent or colorimetric read-outs. Alternatively, we have designed unique multiplexed assays that measured cell death along with biomarkers, and cellular metabolic outcomes. These custom assays provide our clients with robust results at a... Show more »

We utilize a number of cell death assays using standard tests based on fluorescent, luminescent or colorimetric read-outs. Alternatively, we have designed unique multiplexed assays that measured cell death along with biomarkers, and cellular metabolic outcomes. These custom assays provide our clients with robust results at a lower cost and with less test compound and less time. Drs. Lindsey Ott and Karthik Rakmachandran have published manuscripts on some of our novel assays.

Toxicity from drug-drug interactions is important information to obtain early in the drug development process. Likarda has proprietary programming that allows our liquid handling instruments to test for drug-drug interactions in a high-throughput manner, and (if needed) in 3D cell culture.

« Show less
Nikon Inverted Microscope Eclipse TE200
Revco +4 Double Door Refrigerator REL5004A20
ThermoSavant Speedvac DNA120-115
Cancer
Immunoassays
Analytical HPLC
Cardiovascular
neurological
Endocrine
Skeletal
Renal
Cell culture
Drug discovery
in vitro toxicity
ELISA
Agilent 1200 HPLC
Screening
Diabetes
Cell-based assays
BioTek Cytation 5
live-cell imaging
Perkin Elmer Enspire
alphaLISA
Chemiluminescent Immunoassay
Drug Safety and Toxicology
Colorimetric
Fluorescence
in vitro assays
High-throughput data analysis
GMP Material Storage
NanoEnTek EVE automated cell counter
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Thermo Scientific Steri-Cycle Direct Heat C02 Incubators
Zeiss AxioVert Epifluorescence Microscope
Caron Environmental Test Chamber
Caron Photostability Test Chamber
Liver Disease
Fisher Isotemp Chromatography Refrigerator
Rotovap Evaporating System
drug-drug interactions
Cell Viability & Proliferation Assays
Price on request

Cell viability assays are essential for a variety of research questions. We routinely use colorimetric, luminescent and fluorescent detectors of cell viability. For certain scientific goals, cell function may be a better representation of cell viability. We use standard assays or develop novel cell viability tests, depending on the need.

Cell viability assays are essential for a variety of research questions. We routinely use colorimetric, luminescent and fluorescent detectors of cell viability. For certain scientific goals, cell function may be a better representation of cell viability. We use standard assays or develop novel cell viability tests, depending on the need.

« Show less
Mettler Toledo Analytical Balance AG104
Nikon Inverted Microscope Eclipse TE200
Revco +4 Double Door Refrigerator REL5004A20
Thermo Forma CryoMed Control Rate Freezer 7452
Thermo Savant DNA 120 Speed Vac DNA 120-115
Cancer
Cardiovascular
immunology
neurological
Endocrine
Muscular
Skeletal
Cell culture
Drug discovery
ELISA
primary cell culture
Agilent 1200 HPLC
Diabetes
immortalized cell culture
GMP
BioTek Cytation 5
live-cell imaging
Perkin Elmer Enspire
luminescence
cell imaging
Drug Safety and Toxicology
adhesion
Method Development
Method Validation
Colorimetric
Fluorescence
kidney
GMP Material Storage
NanoEnTek EVE automated cell counter
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Thermo Scientific Steri-Cycle Direct Heat C02 Incubators
Zeiss AxioVert Epifluorescence Microscope
Caron Environmental Test Chamber
Caron Photostability Test Chamber
Liver Disease
Fisher Isotemp Chromatography Refrigerator
Eppendorf 5810R Refrigerated Centrifuge
Apoptosis Assays
Price on request

We utilize a number of cell toxicity assays using standard tests based on fluorescent, luminescent or colorimetric read-outs. Alternatively, we have designed unique multiplexed assays that measured cell toxicity, biomarkers, and cellular metabolic outcomes. These custom assays provide our clients with robust results at a lower... Show more »

We utilize a number of cell toxicity assays using standard tests based on fluorescent, luminescent or colorimetric read-outs. Alternatively, we have designed unique multiplexed assays that measured cell toxicity, biomarkers, and cellular metabolic outcomes. These custom assays provide our clients with robust results at a lower cost and with less test compound and less time. Drs. Lindsey Ott and Karthik Rakmachandran have published manuscripts on some of our novel assays.

Toxicity from drug-drug interactions is important information to obtain early in the drug development process. Likarda has proprietary programming that allows our liquid handling instruments to test for drug-drug interactions in a high-throughput manner, and (if needed) in 3D cell culture.

« Show less
Branson Sonifier 250
Nikon Inverted Microscope Eclipse TE200
Revco +4 Double Door Refrigerator REL5004A20
ThermoSavant Speedvac DNA120-115
Cancer
Analytical HPLC
Cardiovascular
neurological
Endocrine
Muscular
pancreatic
Cell culture
Drug discovery
ELISA
primary cell culture
Agilent 1200 HPLC
Diabetes
Cell-based assays
immortalized cell culture
BioTek Cytation 5
live-cell imaging
Dermatology
Perkin Elmer Enspire
luminescence
Drug Safety and Toxicology
Metals Analysis
Colorimetric
Fluorescence
GMP Material Storage
NanoEnTek EVE automated cell counter
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Thermo Scientific Steri-Cycle Direct Heat C02 Incubators
Zeiss AxioVert Epifluorescence Microscope
Caron Environmental Test Chamber
Caron Photostability Test Chamber
Fisher Isotemp Chromatography Refrigerator
Rotovap Evaporating System
Spent Media Analysis
Price on request

Likarda offers spent media analysis with the ability to analyze and detect free amino acids, using an LC automated sample analysis and data processing method. This analysis provides an understanding of changes in media conditions over time and provides a detailed understanding of the changes in culture conditions over time. The... Show more »

Likarda offers spent media analysis with the ability to analyze and detect free amino acids, using an LC automated sample analysis and data processing method. This analysis provides an understanding of changes in media conditions over time and provides a detailed understanding of the changes in culture conditions over time. The method provides sensitive and high‐resolution separation of all amino acids in media. Studying the roles of amino acids during bioprocesses leads to better understanding the feeding strategy, and to improving the yield and quality of the media.

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Mettler Toledo Analytical Balance AG104
Nikon Inverted Microscope Eclipse TE200
Revco +4 Double Door Refrigerator REL5004A20
Cancer
Analytical HPLC
neurological
Endocrine
Muscular
Skeletal
Dental
Diabetes
Cell-based assays
analytical chemistry
BioTek Cytation 5
live-cell imaging
Dermatology
Perkin Elmer Enspire
culture media
cell culture media
amino acids
Metals Analysis
Cellular Compound Screening
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Hamilton Microlab Star Automated Liquid Handling System
Integra VIAFLO Assist automating system
Zeiss AxioVert Epifluorescence Microscope
Caron Environmental Test Chamber
Caron Photostability Test Chamber
Fisher Isotemp Chromatography Refrigerator
Rotovap Evaporating System
Agilent HPLC 1100
Perkin Elmer Optima 7000
Bransonic Ultrasonic Bath Sonicator
Spent Media Analysis
Photostability Studies
Price on request

Early, non-GMP, analysis of compound stability can save time and money later down the drug development pipeline. By utilizing our low-cost stability testing for numerous or single compounds, drug development can be streamlined. Likarda provides photostability storage and testing. We utilize a Caron 6545-1 photostability chamber... Show more »

Early, non-GMP, analysis of compound stability can save time and money later down the drug development pipeline. By utilizing our low-cost stability testing for numerous or single compounds, drug development can be streamlined. Likarda provides photostability storage and testing. We utilize a Caron 6545-1 photostability chamber that is specifically designed to meet ICH, FDA, EMEA and Health Canada requirements for photostability testing according to ICH Q1B Option 2. We are able to provide uniform light intensity (typically UVA at 30 W∙m2 and visible at 30 Klux) and temperature control (10°C to 35°C±2.5°C) with continual monitoring to ensure compliance with each photostability protocol. The independent control of the near UV and cool white lamps allow programming to shut-off lamps based on an exposure level. Exposures are monitored with two light detectors with an integral radiometer to provide precise and accurate light intensity measurement. The light detectors are cosine corrected and calibrated with NIST traceable standards. All storage chambers are fully controlled with 24/7 monitoring, security and alert systems.

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Cancer
Cardiovascular
Endocrine
Muscular
Skeletal
Drug discovery
Diabetes
photostability
stability
environmental stability
Caron Environmental Test Chamber
Caron Photostability Test Chamber
Liver Disease
Neurological Diseases
ICH Stability Testing
Price on request
Request a quote for more information about this service.
HPLC
High Performance Liquid Chromatography
Price on request

Likarda performs HPLC analyses on drug products, pharmaceutical APIs and nutraceutical products. We ran various compendia (USP, BP, JP, and EP) methods or develop methods of analysis for your product. We can perform method development, qualification, transfer and validation per ICH guidelines for accuracy, precision (repeatability... Show more »

Likarda performs HPLC analyses on drug products, pharmaceutical APIs and nutraceutical products. We ran various compendia (USP, BP, JP, and EP) methods or develop methods of analysis for your product. We can perform method development, qualification, transfer and validation per ICH guidelines for accuracy, precision (repeatability and intermediate precision), specificity, limit of detection, limit of quantitation, linearity, range and robustness. We are able to determine sample assay and purity of samples, along with quantitation for solubility, dissolution, diffusion and other techniques requiring quantitation.

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Analytical HPLC
HPLC
Drug discovery
Drug Safety and Toxicology
Agilent 1100 HPLC
Confocal Microscopy
Price on request

Our confocal services include live-cell imaging for fluorescent markers such as calcium ions, and fixed samples. Live-cell images can be collected every 5 seconds, depending on the size of the field of interest, or more quickly for line scans. Three different fluoresent probes can be imaged simultaneously with the system.

Our confocal services include live-cell imaging for fluorescent markers such as calcium ions, and fixed samples. Live-cell images can be collected every 5 seconds, depending on the size of the field of interest, or more quickly for line scans. Three different fluoresent probes can be imaged simultaneously with the system.

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Nikon Inverted Microscope Eclipse TE200
Cancer
Cardiovascular
Endocrine
Muscular
Skeletal
microscopy
Diabetes
Dermatology
American Optical Biostar Tissue Culture Microscope
Zeiss AxioVert Epifluorescence Microscope
Liver Disease
Neurological Diseases
Olympus Fluoview Laser Scanning Confocal Microscope
Immunohistochemistry (IHC)
Price on request

Staff at Likarda have over 45 years of combined experience in immunohistochemistry, and we use this experience to help clients answer a number of questions from test compound effects, function, or target locations. Various fixation technique, counterstains and detection methods are commonly utilized for our clients. Images can... Show more »

Staff at Likarda have over 45 years of combined experience in immunohistochemistry, and we use this experience to help clients answer a number of questions from test compound effects, function, or target locations. Various fixation technique, counterstains and detection methods are commonly utilized for our clients. Images can be captured using confocal microscopy for fluorescent secondary probes, epifluorescent microscopes, or inverted scopes for non-fixed tissue samples.

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Nikon Inverted Microscope Eclipse TE200
LEICA Autostainer
Cancer
Cardiovascular
Endocrine
Muscular
Skeletal
Immunofluorescence
immunohistochemistry
Fluorescent insitu hybridization
Diabetes
American Optical Biostar Tissue Culture Microscope
Olympus Fluoview 300 Laser Scanning Confocal Microscope
Zeiss AxioVert Epifluorescence Microscope
Liver Disease
Neurological Diseases
Renal Disease
Leica Embedding Station
Leica Cryostat
Grant Writing
Price on request

Staff of Likarda have academic experience maintaining a research laboratory on external grants for over 20 years, and was successful in obtaining SBIR and STTR grants, NIH R01s and other R series grants, Dept. of Commerce grants, funding from private non-profit organization, and industry grants. Likarda can serve in a variety of... Show more »

Staff of Likarda have academic experience maintaining a research laboratory on external grants for over 20 years, and was successful in obtaining SBIR and STTR grants, NIH R01s and other R series grants, Dept. of Commerce grants, funding from private non-profit organization, and industry grants. Likarda can serve in a variety of capacities concerning grants by writing the grant, serving as consultants, and even submitting the grant for the client.

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Cancer
Cardiovascular
Endocrine
Muscular
Skeletal
Renal
Diabetes
Dermatology
Liver Disease
Neurological Diseases
Technical Writing
Price on request

Each member of the scientific team at Likarda has an average of more than 15 peer-reviewed manuscripts in journals including Science, Neuron, Journal of Biological Chemistry, American Journal of Physiology, and the Tissue Engineering. Most of our published work is based on our own independent research. In addition, we serve as... Show more »

Each member of the scientific team at Likarda has an average of more than 15 peer-reviewed manuscripts in journals including Science, Neuron, Journal of Biological Chemistry, American Journal of Physiology, and the Tissue Engineering. Most of our published work is based on our own independent research. In addition, we serve as ghost writers for our clients who need assistance with writing. We have experience in writing white papers for our clients, and have created slide decks for public presentations such as at public meetings or for potential investors.

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Cancer
Cardiovascular
neurological
Endocrine
Muscular
Skeletal
Renal
Immune
Diabetes
Immunooncology
Dermatology
Liver Disease
Scientific Manuscript Preparation
Price on request

Each member of the scientific team at Likarda has an average of more than 15 peer-reviewed manuscripts in journals including Science, Neuron, Journal of Biological Chemistry, American Journal of Physiology, and the Tissue Engineering. Most of our published work is based on our own independent research. In addition, we serve as ghost writers for our clients who need assistance with writing.

Each member of the scientific team at Likarda has an average of more than 15 peer-reviewed manuscripts in journals including Science, Neuron, Journal of Biological Chemistry, American Journal of Physiology, and the Tissue Engineering. Most of our published work is based on our own independent research. In addition, we serve as ghost writers for our clients who need assistance with writing.

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Cancer
Cardiovascular
neurological
Endocrine
Muscular
Skeletal
Immune
Diabetes
Immunooncology
Dermatology
kidney
Liver Disease
Chemical Stability Testing
Price on request

Likarda offers environmental testing capabilities. We utilize the Caron 7000 environmental test chamber which is designed in accordance with ICH, Q1A guidelines and is ideal for pharmaceutical stability drug testing, shelf life studies, stability and package testing, temperature elevation studies and more. The standard temperature... Show more »

Likarda offers environmental testing capabilities. We utilize the Caron 7000 environmental test chamber which is designed in accordance with ICH, Q1A guidelines and is ideal for pharmaceutical stability drug testing, shelf life studies, stability and package testing, temperature elevation studies and more. The standard temperature conditions range from 5°C to 70°C with optional operation down to 0°C. Controlled humidity conditions range from 20 to 95% with optional operation down to 2%.

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Drug discovery
Drug Safety and Toxicology
Caron Environmental Test Chamber
Imaging & Spectroscopy
Price on request
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Editorial and Writing Services
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Hit Identification
Price on request
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Optical Microscopy
Price on request
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Chromatography
Price on request
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Purification Services
Price on request
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Biochemistry & Molecular Biology
Price on request
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Toxicology
Price on request
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Project and Process Management
Price on request
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Liquid Chromatography
Price on request
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Analytical Chemistry Services
Price on request
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Formulation Services
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Product Development, Testing, and Packaging
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Chemistry and Materials
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Cells and Tissues
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Pharmacology & Toxicology
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Drug Discovery
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Specialized Cell-Based Assays
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Fluorescence-Based Microscopy
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2018-06-26 20:05:05 +0300

Net Promoter Score of 8 received for 3D Cell-Based Assays.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 8.
2017-10-09 22:55:20 +0300

Net Promoter Score of 8 received for HPLC.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 8.

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