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LigaTrap Technologies, LLC

25 Orders Completed
Raleigh, North Carolina, US

About LigaTrap Technologies, LLC

LigaTrap® Technologies has developed a novel, patented portfolio of affinity ligands specific for the purification of monoclonal and polyclonal immunoglobulins from various species. In addition to species-specific ligands, advantages include the ability to elute bound antibodies at a milder pH (pH 4.0) than proteins A and G (pH ≤ 3.0), thus reducing the potential for precipitation and inactivation of pH sensitive antibodies. Our goal is to generate high purity antibodies using ligands superior to those currently available in the marketplace. The LigaTrap® Team has performed extensive side-by-side testing with purification products that are currently on the market. The LigaTrap® Team has also expanded our capabilities to include our expert Process Development and Downstream Optimization Services. LigaTrap® is actively partnering with technologies and platforms that are rapidly expanding in the Therapeutics Industry.

Our Services (16)


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Antibody Purification

Price on request

COVID plasma purification

COVID-19

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MSD Assays

Price on request

Custom and standard assay services.

10 day turn around on most projects.


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Protein Purification

Price on request

LigaTrap® Technologies has many years of combined expertise in purifying a wide variety of proteins including monoclonal and polyclonal antibodies, recombinant proteins, fusion proteins, affinity-tagged proteins, and native proteins. We offer purification from many formats including (but not limited to) cell culture supernatant, ascites fluid, serum/antiserum, bacterial and mammalian expression systems, avian eggs, etc. We utilize AKTA systems to automate most purification cycles, allowing for increased efficiencies, lower costs, and shorter lead times for our customers. Typical chromatographic strategies used by our purification facility are listed below:

  • LigaTrap® Resin Purification
    • IgG’s, IgY’s, IgA’s, IgM’s
    • Human, Mouse, Rat and many other species
  • Protein A/G/L Purification
  • Affinity Purification
    • Antigen Immunoaffinity
    • IMAC
  • Conventional Chromatography:
    • IEX
    • HIC
    • SEC


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Bioanalytical Assays

Price on request

Analytical testing is an essential part of the proper evaluation and assurance that purified biologicals meet product specifications. Additionally, to ensure integrity of data, it is necessary to have a third-party independent analysis done to confirm internal analytical results. LigaTrap® Technologies offers a variety of different testing services for analysis of purified proteins. Some of these services include SDS-PAGE (native and denaturing), HPLC, Western Blot, ELISA, A280 determination, endotoxin, and bioburden. Discounted pricing is available for customers that have multiple samples and/or multiple assays to be conducted.


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PAGE

Polyacrylamide Gel Electrophoresis
Price on request
Request a quote for more information about this service.

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HPLC

High Performance Liquid Chromatography
Price on request
Request a quote for more information about this service.

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Cell Culture Scale-Up

Price on request

1L Cell culture and purification package

1L cell culture antibody production and purification per cell line


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Western Blot

Price on request
Request a quote for more information about this service.

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ELISA

Enzyme-linked immunosorbent assay
Price on request
Request a quote for more information about this service.

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Chromatography

Price on request
Request a quote for more information about this service.

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Separation/Purification Services

Price on request

Separation/Purification Services


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Bioanalysis

Price on request

Bioanalysis Services


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Antibody Services

Price on request

Antibody Services


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Product Development, Testing, and Packaging

Price on request

Product Development, Testing, and Packaging Services


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Gel Electrophoresis

Price on request

Gel Electrophoresis Services


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Liquid Chromatography (LC)

Price on request

Liquid Chromatography (LC) Services


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JS

Jae Sly

Chief Business Officer
  • Positive review for MSD Assays:

    October 2020

    "The people at LigaTrap are friendly, and generate high quality data quickly!"

LigaTrap Technologies, LLC has not received any endorsements.