Leaf Expression Systems uses the proprietary Hypertrans® expression technologies developed by Prof.George Lomonossoff at the John Innes Centre, UK.
The Hypertrans system allows for the simultaneous production of multiple gene products in a controlled and coordinated manner within the tissues of plants. Using gene synthesis and modular vectors, new products can be developed, validated, scaled and produced very quickly. Potential applications of the technology include:
– Production of complex proteins, such as antibodies or enzymes for research applications.
– Production of antigens including virus-like particles for vaccine development or nano-technology.
– Rapid prototyping and surge production in response to external circumstances.
– Metabolic pathway engineering to generate complex biochemicals that are difficult or impossible to synthesise chemically or are only found in rare species or trace amounts in nature.
Leaf Expression Systems is based in state of the art facilities to produce and engineer its feedstock plants and has industry standard downstream processing capabilities to ensure production quality and bio-security.
We offer services in custom design, expression and purification of client proteins for a range of applications including; therapeutic drugs, vaccine development, diagnostics, biophysical analysis and structural biology. Our key technology is the Hypertrans® system using Agrobacterium-mediated transient eukaryotic expression within Nicotiana benthamiana. The Hypertrans® system promotes extremely high-level and rapid production of proteins without viral replication and is efficient, safe and simple to use.
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