Kitos Biotech is an italian contract research organization foundend in 2016. We are a small team of PhDs in cellular and molecular biology with a background in cancer cell biology. We have more than 100 cell lines to use in our assays and automation systems that let us to provide fast and reliable results.
- Send your compounds as lyophilized or as stock solution.
- Evaluate gene expression levels of ∼2,600 genes involved in 24 cancer-related molecular pathways and/or ∼2,100 miRNA transcripts in our panel of cell lines treated with your favorite compounds.
- Cancer-related gene or miRNA expression levels are determined in our cell lines grown as monolayer or 3D tumor spheroids.
- Bioinformatic analysis is included.
- We manage all the process from cell culture to data analysis.
- You send us the compounds and directly receive ready-to-use results.
- Flexible project planning based on your needs.
- Assess autophagy induction by your compounds in our panel of authenticated cell lines.
- Send your compounds lyophilized or as stock solutions.
- Autophagy is assessed by fluorescence microscopy.
- Mid-throughput screening is performed thanks to lab automation.
- Receive a detailed study report in approximatively one or two months.
- Flexible project planning based on needs.
- IC50, GI50, TGI, LC50 calculations.
- Compounds are accepted both as lyophilized or as stock solution.
- Mid-throughput screening is performed thanks to lab automation.
- Receive a detailed study report in approximatively one or two months.
- Price is referred to technical triplicate for each sample (1 concentration of 1 compound assessed in 1 cell line).
- A multiplexed viability and cytotoxicity assay is performed to distinguish cytostatic and cytotoxic effects.
- Flexible project planning based on needs.
- IC50, GI50, TGI, LC50 calculations.
- Compounds are accepted both as lyophilized or as stock solution.
- Mid-throughput screening is performed thanks to lab automation.
- Receive a detailed study report in approximatively one or two months.
- Price is referred to technical triplicate for each sample (1 concentration of 1 compound assessed in 1 cell line).
- A multiplexed viability and cytotoxicity assay is performed to distinguish cytostatic and cytotoxic effects.
- Flexible project planning based on your needs.
- Assess autophagy induction by your compounds in our panel of authenticated cell lines.
- Send your compounds lyophilized or as stock solutions.
- Autophagy is assessed by fluorescence microscopy.
- Mid-throughput screening is performed thanks to lab automation.
- Receive a detailed study report in approximatively one or two months.
We offer a citotoxicity and proliferation assay to determine kinetic of compound efficacy on 3D tumor spheroids based on live-cell imaging.
Features of the assay
An alternative method to flow cytometry to assess cell cycle using fluorescence microscopy and cell imaging.
Features of the assay
We offer a citotoxicity and proliferation assay to determine kinetic of compound efficacy on 3D tumor spheroids based on live-cell imaging.
Features of the assay
We offer a citotoxicity and proliferation assay to determine kinetic of compound efficacy on 3D tumor spheroids based on live-cell imaging.
Features of the assay
We offer a reliable and broadly employed cell viability assay to determine compound efficacy.
Features of the assay
- Evaluate induction of apoptosis by your compounds on our panel of cell lines.
- The assay measures ex vivo enzymatic activities of caspases 3/7, 8 and 9.
We offer a cell-based assay to measure anti-oxidant activity of tested compound by measuring relative levels of hydrogen peroxide, a reactive oxigen species, in cell culture.
Features of the assay
We offer a cell-based assay to determine potency of histone deacetylase (HDAC) class I and II inhibitors by measuring relative enzymatic activity of HDAC I/II in cell culture.
Features of the assay
We offer a citotoxicity and proliferation assay to determine contribution of ABC transporters to cancer cell chemoresistance of tested compound based on live-cell imaging.
Features of the assay
We offer a cell-based screening to test compound libraries of your choice in your model of interest.
Features of the assay
We have available various commercial libraries of known compounds from Selleckchem:
We can test these libraries in our cell lines or in cells provided by customers.
We can employ any of our assays available in high-throughput:
We can evaluate the combinatorial efficacy of your favorite compound with these libraries to perform drug combination studies.
Selected hits will be validated with the corresponding assay with 11 concentrations of compound.
Protein Expression Visualization Services
Protein Services
Cellular Senescence Assay
- Flexible project planning based on your needs.
- Assess induction of cellular senescence by your compounds in our panel of authenticated cell lines.
- Send your compounds lyophilized or as stock solutions.
- SA-Beta-Gal is assessed by fluorescence microscopy.
- Mid-throughput screening is performed thanks to lab automation.
- Receive a detailed study report in approximatively one or two months
Kitos Biotech has not received any reviews.
“The highly competent and very professional Kitos’ Team provided an excellent and punctual service. It will be a pleasure to work with Kitos again in the future”
“I am very impressed by the quality of the service, very useful to give novel and important insights to our work. Many thanks to the components of the Kitos Biotech Team for their prompt feedback and efficiency, and for their professional support and assistance during all steps of the projects. Mario Sechi, University of Sassari, Italy”
"The service provided by Kitos Biotech was excellent and professional. Your dedication and accuracy were much appreciated" Antonella Obinu, Ph.D. student, University of Pavia.
Kitos Biotech is a young, smart and professional CRO I warmly reccomend: Francesco and his team were very committed, flexible and client-oriented throughout all the period of our collaboration.
Go ahead this way!
We worked with Kitos for a project last year and we were very happy with our collaboration. Kitos is led by motivated scientists and professionals that guarantee the accuracy of their results and are willing to troubleshoot with you whatever aspects you might deem necessary for the success of your project.