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KBioBox LLc

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Worcester, Massachusetts, US

About KBioBox LLc

KBioBox is a bioinformatic technology company powered by proprietary patented genomic search technology, currently offering applications built upon the technology: Gene Editing Design, Off-Target Analysis, and extended GUIDEseq Analysis. The patented technology provides ultra fast bioinformatic searching without compromising accuracy, eliminating research bottlenecks and empowering results. The company was founded by Kryngle Daly Ph.D and partners in 2015.  Daly (CEO) is an experienced bio-computational software developer. KBioBox’s mission is to enhance the competitiveness of it's clients products and solutions by license. KBioBox llc was awarded “Best Bio-Informatics Engine Technology 2018- USA” by Global Health and Pharma.

 

More information on the KBioBox website

Our Services (7)

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Off-Target Genome Editing Analysis

Starting at $200.00 per run

The fastest and most thorough Off Target Analysis available, available for wild type CRISPRs.  A simple “3 click process”. Enter Reference Sequence, Gene Edit Type and Design and in under one minute receive easy to understand annotated reports with visualizations and all locus information.  Primer calculation for off target locations available.

 Additional gene edit chemistries / proteins can be analyzed upon request.

Read our Off Target Analysis "One Pager"

More information on the KBioBox website

Available as:

  • 1 pack
  • 5 pack
  • 10 pack
  • Subscription/License 

Cancer Drug Discovery Genomics Microbiome studies Epigenetics Analysis Analytical analytical testing Analytical Method Development Automation method bioanalysis Biomarker analysis Automated Bioanalytical bioanalytical services Biodata mining bioanalytical methods biotech Cas9 Crispr cell line development Cas9 Crispr System Cas9 Knockin Cas9 Knockout Crispr Cas9 Design CRISPR Cas9 Genome Editing CRISPR Gene Editing Crispr Cas9 Technology CRISPR Cas9 System CRISPR Genetic Engineering CRISPR Genome Engineering CRISPR Knockout CRISPR Knockdown CRISPR Knockin CRISPR Services CRISPR RNA CRISPR-Cas9 CRISPR/Cas9 CRISPR/Cas9 genome editing Crispr Cas9 Editing CRISPR/Cas-9 de novo sequencing drug development gene editing Gene Editing CRISPR Cas9 Gene knockdown Gene Editing QC Gene Knock-in Genetic algoprithms Gene Knock-out Genome editing Genome Engineering Using the CRISPR Cas9 System genomics INDELS microbiome NGS RNA-Seq Illumina Thermo Fisher C++ CRISPR screening Drug Development PacBio Sequel all Sequencing data analysis Target Identification target validation Software development Illumina HiSeq Illumina HiSeq Show 69 more tags Show less
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CRISPR Design to Validation

Starting at $500.00 per run

Design your gene edit target to ensure minimal off target interactions.  KBioBox technology can design your edit in under a minute, providing the "Top Ten" target designs each with a comprehensive Off Target Analysis.  A simple “4 click process”. Enter reference, gene edit location, search type and gene edit type and in under one minute receive easy to understand annotated reports with visualizations  and whole genome off target analysis for each design.

Read our Gene Edit Design "One Pager"

Learn more about the design process on the KBioBox webpage

Learn more about validation on the KBioBox webpage

Available as:

1 pack
5 pack
10 pack
Subscription/License 

Genomics Bioinformatics C++ Human all Cancer Drug Discovery Microbiome studies Epigenetics Analytical Analytical Development analytical testing Automated Automation method Bioinformatics pipelines bioanalytical methods bioanalytical services Biodata mining Biomarker analysis biotech Cas9 Crispr Cas9 Crispr System Cas9 Knockin Cas9 Knockout CRISPR Crispr Cas Gene Editing CRISPR Cas9 Crispr Cas9 Design CRISPR Cas9 System Crispr Cas9 Editing CRISPR Services CRISPR Cas9 Genome Editing CRISPR Cas9 Gene Editing Technology Crispr Cas9 Technology CRISPR Gene Editing CRISPR-Cas9 CRISPR/Cas-9 CRISPR Genetic Engineering CRISPR Genome Engineering CRISPR Knockdown CRISPR/Cas9 genome editing CRISPR/Cas9 CRISPR Knockin CRISPR Knockout CRISPR RNA de novo sequencing Data analysis gene editing Gene Editing CRISPR Cas9 Gene Knock-in Gene Knock-out gene targeting Genome editing Genetic algoprithms genomics microbiome Microbiome Diagnostic Services Genome Engineering Using the CRISPR Cas9 System INDELS NGS RNA-Seq Illumina HiSeq Illumina PacBio Sequel Thermo Fisher mammal Plants CRISPR screening Drug Development Sequencing data analysis target validation Target Identification Software development Sanger Sequencing Illumina HiSeq Show 75 more tags Show less
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TALEN Design and Validation

Price on request

Design your gene edit target to ensure minimal off target interactions.  KBioBox llc technology can design your edit in under a minute, providing the "Top Ten" target designs each with a comprehensive Off Target Analysis.  A simple “3 click process”. Enter reference, gene edit location, search type and gene edit type and in under one minute receive easy to understand annotated reports with visualizations  and whole genome off target analysis for each design.

Read our Gene Edit Design "One Pager"

Learn more about gene edit design on the KBioBox webpage

Available as:

1 pack
5 pack
10 pack
Subscription/License 

Cancer Drug Discovery Genomics Microbiome studies Analytical Development analytical testing Bioinformatics Bioinformatics pipelines gene editing Gene Knock-in Gene Knock-out gene targeting genomics Gene-Targeting Service C++ Genome editing Sanger Sequencing Genetic algoprithms NGS NGS Custom Data Sequencing data analysis INDELS Target Identification target validation target discovery Software development Drug Development all Animals Human Plants Show 31 more tags Show less
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GUIDE-seq Analysis

Genome-wide Unbiased Identification of Double-stranded breaks Enabled by Sequencing Analysis
Starting at $5,000.00 per run

KBioBox Extended GUIDE-Seq analysis significantly enhances the standard procedure and identifies actual cleavage sites, correct and incorrect repairs, observed and potential translocations and the changes to peptide/protien sequences.

Read our Extended GUIDE-Seq Analysis "One Pager"

Learn more about our extended GUIDE-Seq Analysis on the KBioBox website

Available as:

1 pack
2 pack
3 pack
Subscription/License 

Cancer Illumina HiSeq Genomics Drug Discovery Analysis Analytical Development analytical testing Automated Automation method Automation method installation bioanalysis Bioanalytical Bioinformatics Bioinformatics pipelines CRISPR Crispr Cas Gene Editing CRISPR Cas9 Crispr Cas9 Design CRISPR Cas9 Gene Editing Technology Crispr Cas9 Editing CRISPR Cas9 Genome Editing Cas9 Crispr CRISPR-Cas9 CRISPR Services CRISPR/Cas9 genome editing CRISPR RNA CRISPR/Cas-9 Crispr Cas9 Technology Computational Drug Discovery Collaborative R&D CRISPR Gene Editing CRISPR Genome Engineering CRISPR Knockin CRISPR Knockout DNA-Seq drug discovery gene editing Genome Engineering Using the CRISPR Cas9 System gene targeting Gene Editing CRISPR Cas9 Genome editing Genetic algoprithms Gene-Targeting Gene-Targeting Service INDELS RNA-Seq RNA sequencing rRNA Target Identification target validation Sequencing data analysis Sanger Sequencing mouse breeding Software development Illumina PacBio Sequel Thermo Fisher Illumina HiSeq C++ Animals Human Plants CRISPR screening Drug Development all Show 65 more tags Show less
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CRISPR Bioinformatics

Price on request

Design, check for Off Targets, then verify an edit receiving information on cleavage sites, correct and incorrect repairs, observerd/potential translocations with changes to peptide sequences.

Read our Gene Edit Design "one pager"

Read our Off Target Analysis "one pager'

Read our Extended GUIDE-Seq "one pager"

 

Genetic Disease Cancer Genetic Disease Illumina HiSeq Drug Discovery Genomics Microbiome studies Analysis Analytical Analytical Development Analytical Method Development analytical testing Automated automated method bioanalysis Bioanalytical bioanalytical methods Biodata mining Biomarker analysis biotech Cas9 Crispr Cas9 Crispr System Cas9 Knockin Cas9 Knockout Crispr Cas9 Design Crispr Cas9 Editing CRISPR Cas9 Gene Editing Technology CRISPR Cas9 Genome Editing Crispr Cas Gene Editing CRISPR Cas9 System Crispr Cas9 Technology CRISPR/Cas-9 CRISPR/Cas9 genome editing CRISPR Knockin CRISPR Knockout de novo sequencing de novo drug development CRISPR Genome Engineering Genome editing Genome Engineering Using the CRISPR Cas9 System gene editing Gene Editing CRISPR Cas9 Gene Knock-in Gene Knock-out Genetic algoprithms genome Engineering microbiome Microbiome Diagnostic Services NGS NGS Custom Data Illumina PacBio Sequel Thermo Fisher C++ Animals Human Plants Drug Development CRISPR screening all Show 61 more tags Show less
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Bioinformatics

Price on request

Have a unique bio-informatics challenge, or "open source" solutions not providing needed answers?  KBioBox's novell patented "inverted" bio-informatics engine handles data sets of any size and can find even the smallest needle in the haystack.  Contact us to see how KBioBox can support your efforts.

Learn more on KBioBox's webpage

Cancer Illumina HiSeq Drug Discovery Genomics Microbiome studies Analysis Analytical Analytical Method Development analytical testing Automated automated method Biodata mining Cas9 Crispr Cas9 Crispr System Cas9 Knockin Cas9 Knockout Crispr Cas9 Design Crispr Cas9 Editing Crispr Cas Gene Editing CRISPR Cas9 Gene Editing Technology CRISPR Cas9 Genome Editing CRISPR Cas9 CRISPR de novo de novo sequencing NGS NGS Custom Data RNA-Seq CRISPR Genome Engineering microbiome Illumina PacBio Thermo Fisher C++ Animals Human Plants CRISPR screening microbiome Drug Development all Show 41 more tags Show less
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Software Development

Price on request

Develop and automate your pipelines, reducing human time and increasing efficiency.  In house or web based KBioBox can develop and deploy custom bio-informatic platforms to fit your needs.

Learn more on KBioBox's webpage

Cancer Illumina HiSeq Drug Discovery Genomics Cas9 Crispr System Crispr Cas Gene Editing Crispr Cas9 Design Cas9 Crispr CRISPR Cas9 Gene Editing Technology Software development software workflow Microbiome Diagnostic Services microbiome Analysis Analytical Analytical Method Development Analytical Development bioanalysis Bioinformatics Bioinformatics pipelines structural bioinformatics NGS NGS Custom Data Illumina C++ de novo sequencing de novo Human Animals Plants microbiome Pharmacogenomics all Show 33 more tags Show less

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  • MP

    Michael PowellJuly 2019

    KBioBox is an excellent resource for genomic analysis and gene editing CRISPR gRNA design and off-target analysis they helped us immensely in our CRISPR gene-editing projects.

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