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KBioBox LLc

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Worcester, Massachusetts, US

About KBioBox LLc

KBioBox is a bioinformatic technology company powered by proprietary patented genomic search technology, currently offering applications built upon the technology: Gene Editing Design, Off-Target Analysis, and extended GUIDEseq Analysis. The patented technology provides ultra fast bioinformatic... Show more »

KBioBox is a bioinformatic technology company powered by proprietary patented genomic search technology, currently offering applications built upon the technology: Gene Editing Design, Off-Target Analysis, and extended GUIDEseq Analysis. The patented technology provides ultra fast bioinformatic searching without compromising accuracy, eliminating research bottlenecks and empowering results. The company was founded by Kryngle Daly Ph.D and partners in 2015.  Daly (CEO) is an experienced bio-computational software developer. KBioBox’s mission is to enhance the competitiveness of it's clients products and solutions by license. KBioBox llc was awarded “Best Bio-Informatics Engine Technology 2018- USA” by Global Health and Pharma.

 

More information on the KBioBox website

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Our Services (7)


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Off-Target Genome Editing Analysis

Starting at $200.00 per run

The fastest and most thorough Off Target Analysis available, available for wild type CRISPRs.  A simple “3 click process”. Enter Reference Sequence, Gene Edit Type and Design and in under one minute receive easy to understand annotated reports with visualizations and all locus information.  Primer... Show more »

The fastest and most thorough Off Target Analysis available, available for wild type CRISPRs.  A simple “3 click process”. Enter Reference Sequence, Gene Edit Type and Design and in under one minute receive easy to understand annotated reports with visualizations and all locus information.  Primer calculation for off target locations available.

 Additional gene edit chemistries / proteins can be analyzed upon request.

Read our Off Target Analysis "One Pager"

More information on the KBioBox website

Available as:

  • 1 pack
  • 5 pack
  • 10 pack
  • Subscription/License 
Show less
Illumina HiSeq C++ all Cancer gene editing RNA-Seq Genetic algoprithms NGS Biomarker analysis Gene Knock-out Automated Gene knockdown Gene Editing QC Biodata mining Sequencing data analysis Software development de novo sequencing Gene Knock-in target validation cell line development bioanalysis drug development Cas9 Crispr System Cas9 Crispr CRISPR Cas9 Genome Editing Cas9 Knockin Cas9 Knockout CRISPR Cas9 System Crispr Cas9 Design Crispr Cas9 Editing Crispr Cas9 Technology CRISPR Gene Editing CRISPR Knockin CRISPR Knockout CRISPR Genetic Engineering CRISPR Genome Engineering CRISPR Knockdown CRISPR RNA CRISPR Services Gene Editing CRISPR Cas9 Genome Engineering Using the CRISPR Cas9 System Genome editing Target Identification Bioanalytical Analytical Method Development Analytical analytical testing microbiome CRISPR/Cas9 CRISPR-Cas9 INDELS genomics CRISPR/Cas9 genome editing Analysis Automation method bioanalytical methods bioanalytical services CRISPR/Cas-9 biotech Drug Discovery Genomics Microbiome studies Epigenetics CRISPR screening Drug Development Illumina Illumina HiSeq Thermo Fisher PacBio Sequel Show 69 more tags Show less

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CRISPR Design to Validation

Starting at $500.00 per run

Design your gene edit target to ensure minimal off target interactions.  KBioBox technology can design your edit in under a minute, providing the "Top Ten" target designs each with a comprehensive Off Target Analysis.  A simple “4 click process”. Enter reference, gene edit location, search type and gene... Show more »

Design your gene edit target to ensure minimal off target interactions.  KBioBox technology can design your edit in under a minute, providing the "Top Ten" target designs each with a comprehensive Off Target Analysis.  A simple “4 click process”. Enter reference, gene edit location, search type and gene edit type and in under one minute receive easy to understand annotated reports with visualizations  and whole genome off target analysis for each design.

Read our Gene Edit Design "One Pager"

Learn more about the design process on the KBioBox webpage

Learn more about validation on the KBioBox webpage

Available as:

1 pack
5 pack
10 pack
Subscription/License 

Show less
Illumina HiSeq Human Plants mammal C++ all Cancer CRISPR gene editing Bioinformatics pipelines RNA-Seq Genetic algoprithms NGS Biomarker analysis Gene Knock-out Automated Bioinformatics Data analysis Biodata mining Sequencing data analysis Software development de novo sequencing Gene Knock-in target validation Cas9 Crispr System Cas9 Crispr CRISPR Cas9 Genome Editing Cas9 Knockin Cas9 Knockout CRISPR Cas9 System CRISPR Cas9 Crispr Cas Gene Editing Crispr Cas9 Design Crispr Cas9 Editing CRISPR Cas9 Gene Editing Technology Crispr Cas9 Technology CRISPR Gene Editing CRISPR Knockin CRISPR Knockout CRISPR Genetic Engineering CRISPR Genome Engineering CRISPR Knockdown CRISPR RNA CRISPR Services Gene Editing CRISPR Cas9 Genome Engineering Using the CRISPR Cas9 System Genome editing Target Identification Analytical Development Analytical analytical testing Microbiome Diagnostic Services microbiome gene targeting CRISPR/Cas9 CRISPR-Cas9 INDELS genomics CRISPR/Cas9 genome editing Automation method Sanger Sequencing bioanalytical methods bioanalytical services CRISPR/Cas-9 biotech Drug Discovery Genomics Microbiome studies Epigenetics CRISPR screening Drug Development Illumina Illumina HiSeq Thermo Fisher PacBio Sequel Show 75 more tags Show less

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TALEN Design and Validation

Price on request

Design your gene edit target to ensure minimal off target interactions.  KBioBox llc technology can design your edit in under a minute, providing the "Top Ten" target designs each with a comprehensive Off Target Analysis.  A simple “3 click process”. Enter reference, gene edit location,... Show more »

Design your gene edit target to ensure minimal off target interactions.  KBioBox llc technology can design your edit in under a minute, providing the "Top Ten" target designs each with a comprehensive Off Target Analysis.  A simple “3 click process”. Enter reference, gene edit location, search type and gene edit type and in under one minute receive easy to understand annotated reports with visualizations  and whole genome off target analysis for each design.

Read our Gene Edit Design "One Pager"

Learn more about gene edit design on the KBioBox webpage

Available as:

1 pack
5 pack
10 pack
Subscription/License 

Show less
Human Plants Animals C++ all Cancer gene editing Bioinformatics pipelines Genetic algoprithms NGS Gene Knock-out Bioinformatics Sequencing data analysis Software development Gene Knock-in target validation Gene-Targeting Service Genome editing Target Identification Analytical Development analytical testing gene targeting INDELS genomics NGS Custom Data Sanger Sequencing target discovery Drug Discovery Genomics Microbiome studies Drug Development Show 31 more tags Show less

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GUIDE-seq Analysis

Genome-wide Unbiased Identification of Double-stranded breaks Enabled by Sequencing Analysis
Starting at $5,000.00 per run

KBioBox Extended GUIDE-Seq analysis significantly enhances the standard procedure and identifies actual cleavage sites, correct and incorrect repairs, observed and potential translocations and the changes to peptide/protien sequences.

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KBioBox Extended GUIDE-Seq analysis significantly enhances the standard procedure and identifies actual cleavage sites, correct and incorrect repairs, observed and potential translocations and the changes to peptide/protien sequences.

Read our Extended GUIDE-Seq Analysis "One Pager"

Learn more about our extended GUIDE-Seq Analysis on the KBioBox website

Available as:

1 pack
2 pack
3 pack
Subscription/License 

Show less
Illumina HiSeq Human Plants Animals C++ all Cancer CRISPR gene editing Bioinformatics pipelines RNA-Seq Genetic algoprithms DNA-Seq Automated Bioinformatics RNA sequencing Sequencing data analysis Software development target validation bioanalysis Cas9 Crispr CRISPR Cas9 Genome Editing CRISPR Cas9 Crispr Cas Gene Editing Crispr Cas9 Design Crispr Cas9 Editing CRISPR Cas9 Gene Editing Technology Crispr Cas9 Technology CRISPR Gene Editing CRISPR Knockin CRISPR Knockout CRISPR Genome Engineering CRISPR RNA CRISPR Services Gene Editing CRISPR Cas9 Gene-Targeting Service Gene-Targeting Genome Engineering Using the CRISPR Cas9 System Genome editing Collaborative R&D Target Identification Bioanalytical Analytical Development analytical testing gene targeting CRISPR-Cas9 INDELS mouse breeding CRISPR/Cas9 genome editing drug discovery Computational Drug Discovery Analysis Automation method Automation method installation Sanger Sequencing rRNA CRISPR/Cas-9 Drug Discovery Genomics CRISPR screening Drug Development Illumina Illumina HiSeq Thermo Fisher PacBio Sequel Show 65 more tags Show less

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CRISPR Bioinformatics

Price on request

Design, check for Off Targets, then verify an edit receiving information on cleavage sites, correct and incorrect repairs, observerd/potential translocations with changes to peptide sequences.

Show more »

Design, check for Off Targets, then verify an edit receiving information on cleavage sites, correct and incorrect repairs, observerd/potential translocations with changes to peptide sequences.

Read our Gene Edit Design "one pager"

Read our Off Target Analysis "one pager'

Read our Extended GUIDE-Seq "one pager"

 

Show less
Illumina HiSeq Genetic Disease Human Plants Animals C++ all Cancer Genetic Disease gene editing Genetic algoprithms NGS Biomarker analysis Gene Knock-out Automated Biodata mining de novo de novo sequencing Gene Knock-in bioanalysis drug development Cas9 Crispr System Cas9 Crispr CRISPR Cas9 Genome Editing Cas9 Knockin Cas9 Knockout CRISPR Cas9 System Crispr Cas Gene Editing Crispr Cas9 Design Crispr Cas9 Editing CRISPR Cas9 Gene Editing Technology Crispr Cas9 Technology CRISPR Knockin CRISPR Knockout CRISPR Genome Engineering Gene Editing CRISPR Cas9 Genome Engineering Using the CRISPR Cas9 System Genome editing Bioanalytical Analytical Development Analytical Method Development Analytical analytical testing Microbiome Diagnostic Services microbiome CRISPR/Cas9 genome editing Analysis NGS Custom Data bioanalytical methods CRISPR/Cas-9 biotech automated method genome Engineering Drug Discovery Genomics Microbiome studies CRISPR screening Drug Development Illumina Thermo Fisher PacBio Sequel Show 61 more tags Show less

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Bioinformatics

Price on request

Have a unique bio-informatics challenge, or "open source" solutions not providing needed answers?  KBioBox's novell patented "inverted" bio-informatics engine handles data sets of any size and can find even the smallest needle in the haystack.  Contact us to see how KBioBox can support your efforts.

Show more »

Have a unique bio-informatics challenge, or "open source" solutions not providing needed answers?  KBioBox's novell patented "inverted" bio-informatics engine handles data sets of any size and can find even the smallest needle in the haystack.  Contact us to see how KBioBox can support your efforts.

Learn more on KBioBox's webpage

Show less
Illumina HiSeq Human Plants Animals C++ all Cancer CRISPR RNA-Seq NGS Automated Biodata mining de novo de novo sequencing Cas9 Crispr System Cas9 Crispr CRISPR Cas9 Genome Editing Cas9 Knockin Cas9 Knockout CRISPR Cas9 Crispr Cas Gene Editing Crispr Cas9 Design Crispr Cas9 Editing CRISPR Cas9 Gene Editing Technology CRISPR Genome Engineering Analytical Method Development Analytical analytical testing microbiome Analysis NGS Custom Data automated method Drug Discovery Genomics Microbiome studies CRISPR screening Drug Development microbiome Illumina PacBio Thermo Fisher Show 41 more tags Show less

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Software Development

Price on request

Develop and automate your pipelines, reducing human time and increasing efficiency.  In house or web based KBioBox can develop and deploy custom bio-informatic platforms to fit your needs.

Learn more on KBioBox's webpage

Develop and automate your pipelines, reducing human time and increasing efficiency.  In house or web based KBioBox can develop and deploy custom bio-informatic platforms to fit your needs.

Learn more on KBioBox's webpage

Show less
Illumina HiSeq Human Plants Animals de novo de novo sequencing C++ all Cancer Bioinformatics pipelines NGS Bioinformatics Software development structural bioinformatics bioanalysis Cas9 Crispr System Cas9 Crispr Crispr Cas Gene Editing Crispr Cas9 Design CRISPR Cas9 Gene Editing Technology Analytical Development Analytical Method Development Analytical Microbiome Diagnostic Services microbiome Analysis software workflow NGS Custom Data Drug Discovery Genomics Pharmacogenomics microbiome Illumina Show 33 more tags Show less

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    Michael PowellJuly 2019

    KBioBox is an excellent resource for genomic analysis and gene editing CRISPR gRNA design and off-target analysis they helped us immensely in our CRISPR gene-editing projects.

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