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Jubilant Biosys Limited

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Noida, Uttar Pradesh, IN

About Jubilant Biosys Limited

Jubilant Biosys Limited (JBL) & Jubilant Chemsys Limited (JCL) (JBL and JCL are collectively referred to as Jubilant) are sister concerns of Jubilant Life Sciences (a $1,310 MM Sales Corporation) providing innovative drug discovery services to the global life sciences, agro-chemicals and specialty chemicals industry through its research centers in India.

Jubilant’s services in discovery research includes;

·         Target identification/ target validation to lead optimization/ preclinical candidate, for multiple therapeutic areas viz; oncology, metabolic disorders, CNS, pain, inflammation, fibrosis and respiratory diseases.

·         Functional services comprising of computational chemistry/ molecular modeling, medicinal chemistry, synthetic chemistry, scale-up (Non-GMP & GMP), structural biology, ADME-PK, in-vitro and in-vivo biology and IND enabling GLP toxicology.

 

1.      Key Statistics:
·         Founded in 2000; worked with global top-10 pharma, mid-sized and biotech companies.

·         750+ people working on drug discovery services business.

·         75+ integrated programs experience with 12 successfully delivered at lead optimization/ IND stage.

·         Multi-location: Research centers spread across two locations Noida and Bengaluru in India.

·         Customized business models fit to serve customer needs;

o   Full Time Equivalent (FTE) based,

o   Fee For Service (FFS) based,

o   Risk share and Milestone based for integrated research programs

Certifications & Qualifications

AAALAC GLP GMP ISO 14001 ISO 18001 ISO 9001

Our Services (63)


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Machine Learning and AI Solutions

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Co-Crystallization

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Protein Production

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Western Blot

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Process and Scale-Up Chemistry

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Chemistry, Manufacturing and Controls (CMC)

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Integrated Drug Discovery

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Computational Drug Discovery

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Compound Library Design

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Drug Target Validation

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Bioinformatics, Target proposal (line-of-sight to IND), Target Validation (siRNA, tool compounds, expression)
Build: Target and pathway expression in human disease tissue, patient stratification.


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Drug Target Identification

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Bioinformatics, Target proposal (line-of-sight to IND), Target Validation (siRNA, tool compounds, expression)
Build: Target and pathway expression in human disease tissue, patient stratification.


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Hit to Lead and Lead Optimization

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HTS, Structural Biology (protien, X-ray crystallography), Med/Comp Chem, in vitro ADME, in vitro/Cell Biology
Build: Fragment and Lead Library synthesis, human cells (primary).


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In vivo PK/PD Studies

Price on request

Assessment of physicochemical and in vitro ADME properties:
In silico properties, Solubility, Log D, Microsomal stability, CYP inhibition

Optimization of druggable properties, IVIVC, PK/PD correlation:
In vivo PK (Rodent and Non- Rodent), PK/PD, Plasma protein binding, Blood/Plasma partioning


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Medicinal Chemistry

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Expanded Synthetic Chemistry, Scale-Up facility, Pre-formulation and formulation development

Special Expertise: Carbohydrate Chemistry, Nucleoside Chemistry, Focused Libraries


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Cell Culture Scale-Up

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Process Research and Development, Multi Kg (Non-GMP) manufacturing upto 10Kg of GMP material manufacturing capability


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Chemical Synthesis

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Synthesis of scaffolds, building blocks, intermediates, reference compounds. Expert in Synthetic Organic Chemistry

milligram gram kilogram

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Compound Library Synthesis

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Library Design and Synthesis of Compounds and Focused Library Design


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Drug Discovery

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Comprehensive Drug Discovery services - from target discovery to candidate selection in partnership with leading healthcare companies, spanning Target Identification/Validation to Lead Optimisation/Pre-clinical candidate selection. With focus on Oncology, Metabolic Disorders, Central Nervous System diseases, Pain and Inflammation,GI diseases, Respiratory Diseases and Fibrosis


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Combinatorial Chemistry

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Jubilant also has Combinatorial Chemistry expertise


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Chiral Resolution

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Chiral Resolution of Compounds, SFC, Other advanced Analytical Services are offered as support to synthesis quotations and on a standalone basis.


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Computational Chemistry

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Computational chemistry - Molecular modelling studies - pharmacophore and QSAR modeling, protein structure based drug design, ligand based drug design, homology modeling, docking and scoring.


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Chemical Stability Testing

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Melting Point Determination

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Optical Rotation

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UV-VIS Spectroscopy

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Nucleic Acid Services

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Animal Models and Studies

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Structure-Based Drug Design

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Lead Identification and Validation

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Toxicology

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Bioconjugation/Chemical Crosslinking

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Synthetic Building Blocks and Intermediates

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Elemental Analysis

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Drug Release Studies/In Vitro Release Testing (IVRT)

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LogP/LogD Determination

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pKa Measurement

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Residual Impurity Analysis

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In vitro ADME/DMPK Studies

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ADME/DMPK Studies

Drug Metabolism and Pharmacokinetics
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ADME and DMPK Studies Services


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Systems Biology

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Peptide Synthesis

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Hit Identification

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In vitro Pharmacology Studies

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Drug Development

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Structural Biology

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Compound Libraries

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Chemistry and Materials

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Cells and Tissues

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Spectroscopy

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Drug Discovery & Development

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DNA Library Services

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Analytical Chemistry Services

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Pharmacology & Toxicology

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DNA Services

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Imaging & Spectroscopy

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Contract Research

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Contract Services Directory

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Synthetic Chemistry

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Biology

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Biochemistry & Molecular Biology

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Separation/Purification Services

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Spectrophotometry

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Mammalian Cell Culture

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