T9jyhi2fqmek3f70oz5h iqbio

iQ Biosciences

10 Orders Completed
Berkeley, California, US

About iQ Biosciences

Divison of: QB3

At iQ Biosciences, we provide focused research support to the pharmaceutical, biotechnology, and diagnostic industries in the form of intelligent research services and quality biospecimens. We are driven to go beyond being reliable – we excel at being a trusted partner in the biomedical community to help cure... Show more »

At iQ Biosciences, we provide focused research support to the pharmaceutical, biotechnology, and diagnostic industries in the form of intelligent research services and quality biospecimens. We are driven to go beyond being reliable – we excel at being a trusted partner in the biomedical community to help cure disease.

iQ Biosciences offers Bioservices for Research Testing, Drug Discovery, and Preclinical Studies that can help determine a drug product’s safety and mechanism of action. These services include testing services, in-vitro based safety or toxicology assays, and functional characterization using in-vitro assays or in-vivo pharmacology models.

We believe it’s urgent to help the biomedical research community deliver on therapeutic promises today.

We believe all researchers should have access to the highest standards of testing services and investigative approaches for qualitatively assessing or quantitatively measuring their test compound’s bioactivity at practical prices.

Show less

Our Services (56)


ic

Cytokine Release Assay

Price on request

-Help predict cytokine release (i.e. cytokine storms) induced by antibody-based therapeutics in first in-human trials or primate safety studies with iQ’s Cytokine Release Assay
-Assess cytokine release in response to therapeutic molecules using appropriately designed studies based on our direct experience with FDA feedback... Show more »

-Help predict cytokine release (i.e. cytokine storms) induced by antibody-based therapeutics in first in-human trials or primate safety studies with iQ’s Cytokine Release Assay
-Assess cytokine release in response to therapeutic molecules using appropriately designed studies based on our direct experience with FDA feedback (pre-IND meeting comments, etc.)
-Data is provided in appropriate formats, including raw data, PowerPoint slide summary, and appropriate report format to supplement potential IND or EMA filings
-All assays and methods are performed according to FDA and EMA recommended guidelines
-Our high throughput system and work flow with qualified donors give you high quality results with rapid turnaround

Show less

ic

In vitro Hemolysis Assay

Price on request

-Evaluate your small molecule, biologic, or formulation excipients for its potential to lyse red blood cells
-Personalized experimental design to ensure the most relevant data is obtained with the options to examine all relevant in vivo pharmacologically relevant blood from appropriate species
-All assays are performed with high-quality reagents and strict controls by experienced immunologists

-Evaluate your small molecule, biologic, or formulation excipients for its potential to lyse red blood cells
-Personalized experimental design to ensure the most relevant data is obtained with the options to examine all relevant in vivo pharmacologically relevant blood from appropriate species
-All assays are performed with high-quality reagents and strict controls by experienced immunologists

Show less

ic

ADCC and CDC Assays

Price on request

-Examine ADCC activity of your therapeutic antibody with iQ’s antibody-dependent cellular cytotoxicity assay (ADCC assay)
-We utilize two different approaches to evaluate ADCC activity:
-ADCC reporter assays using cell lines that have either the V Variant or F Variant of position 158 of the FcgRIIIa receptor
-ADCC... Show more »

-Examine ADCC activity of your therapeutic antibody with iQ’s antibody-dependent cellular cytotoxicity assay (ADCC assay)
-We utilize two different approaches to evaluate ADCC activity:
-ADCC reporter assays using cell lines that have either the V Variant or F Variant of position 158 of the FcgRIIIa receptor
-ADCC assays using primary cells (PBMCs, isolated NK cells) that have been characterized for V Variant or F Variant of position 158 of the FcgRIIIa receptor
-Personalized experimental design to ensure the most biologically relevant data is obtained
-Assays can be performed with purified effector cells or PBMCs
-Cell line expressing target antigen can be developed
-All assays are performed with high-quality reagents and strict controls by experienced immunologists

CDC Assays
-Help predict the potential magnitude of complement-mediated target lysis conferred by your therapeutic antibody with iQ’s complement-dependent cytotoxicity (CDC) assay
-Personalized experimental design to ensure the most relevant CDC inhibition data (IC50s) are generated with your molecules
-All assays are performed with high-quality reagents and strict controls by experienced immunologists
-Data is provided in appropriate formats, including PowerPoint slides and/or direct data files

Show less

ic

In vitro Antibody-Drug Conjugate Toxicity Testing

Price on request

-Evaluate your therapeutic antibody for internalization and antibody drug conjugate cytotoxicity potential
-Our workflow utilizes a two-step approach to evaluate potential ADC activity:
-Measurement of internalization kinetics on appropriate cell lines using your antibody
-Measurement of ADC mediated cytotoxicity... Show more »

-Evaluate your therapeutic antibody for internalization and antibody drug conjugate cytotoxicity potential
-Our workflow utilizes a two-step approach to evaluate potential ADC activity:
-Measurement of internalization kinetics on appropriate cell lines using your antibody
-Measurement of ADC mediated cytotoxicity potential using appropriate secondary antibodies conjugated to a ribosome-inactivating protein
-Personalized experimental design to ensure the most relevant biological data is obtained
-All assays are performed with high-quality reagents and strict controls by experienced immunologists

Show less

ic

Immune Checkpoint Assays

Price on request

Immune Checkpoint Interaction Assay:

  • Evaluate your immune checkpoint (CTLA-4, PD-1, TIM-3, LAG-3, TIGIT, OX40, GITR, etc.) biologic or molecule for specific binding to the receptor using ELISA or iQ’s cell line-based binding assay
  • Binding affinities (EC50s) or binding inhibition (IC50s) can be generated with your... Show more »

Immune Checkpoint Interaction Assay:

  • Evaluate your immune checkpoint (CTLA-4, PD-1, TIM-3, LAG-3, TIGIT, OX40, GITR, etc.) biologic or molecule for specific binding to the receptor using ELISA or iQ’s cell line-based binding assay
  • Binding affinities (EC50s) or binding inhibition (IC50s) can be generated with your molecules
  • Personalized experimental design to ensure the most relevant data is obtained
  • All assays are performed with high-quality reagents and strict controls by experienced immunologists

Immune Checkpoint Functional Assay:

  • Evaluate your immune checkpoint (CTLA-4, PD-1, TIM-3, LAG-3, TIGIT, OX40, GITR, etc.) biologic or small molecules in functional assays
  • Assays to measure activity (CellTiter-Glo, LDH, etc.) can be performed with appropriate cell lines that express your biologically relevant target in presence of your biologic or molecules
  • Assays to measure proliferation, expression of cell surface activation markers, and cytokine expression can be performed with primary cells using non-antigen specific (superantigens) or antigen specific approaches in the presence of your molecule
  • Personalized experimental design to ensure the most relevant data is obtained
  • All assays are performed with high-quality reagents and strict controls by experienced immunologists
Show less

ic

Flow Cytometry

Price on request
Request a quote for more information about this service.

ic

Immunophenotyping

Price on request
Request a quote for more information about this service.

ic

Endotoxin Testing

Price on request

We measure the amount of endotoxin in a protein, peptide, or antibody sample using the Limulus Amebocyte Lysate (LAL) chromogenic assay. Known concentrations of E. coli O111:B4 are used as our standard for accurate endotoxin quantitation. The sensitivity of our assay can detect as little as 0.1 EU/mL (approximately 0.01ng... Show more »

We measure the amount of endotoxin in a protein, peptide, or antibody sample using the Limulus Amebocyte Lysate (LAL) chromogenic assay. Known concentrations of E. coli O111:B4 are used as our standard for accurate endotoxin quantitation. The sensitivity of our assay can detect as little as 0.1 EU/mL (approximately 0.01ng endotoxin per mL).

iQ Biosciences research professionals have performed thousands of endotoxin testing assays for clients. We provide a fast turnaround time and the highest quality testing to determine if test samples are endotoxin-free and safe for in-vitro or in-vivo research use.

Show less

ic

In vivo Immunogenicity Assays

Price on request
  • Evaluate your small molecule, biologic, or formulation excipients for its potential to bind or activate primary cells from multiple species (human, non-human primate, rodent)
  • We routinely perform immunophenotyping of in vitro or in vivo (safety, PD, xenograft, or clinical studies) treated samples (cell lines or primary cells)... Show more »
  • Evaluate your small molecule, biologic, or formulation excipients for its potential to bind or activate primary cells from multiple species (human, non-human primate, rodent)
  • We routinely perform immunophenotyping of in vitro or in vivo (safety, PD, xenograft, or clinical studies) treated samples (cell lines or primary cells) for specific protein target expression on cell subsets or biomarker detection indicative of bioactivity (cell surface activation markers, cytokine detection)
  • Personalized experimental design to ensure the most biologically relevant data is obtained
  • These assays are applicable to multiple species (human, non-human primates, & rodents) for cross-reactivity assessment of your molecules
  • All assays are performed with high-quality reagents and strict controls by experienced immunologists
Show less
Human Mouse Rat Rodents Non-human primates (NHP)

ic

In vitro Immunogenicity Assays

Price on request
  • Evaluate your small molecule, biologic, or formulation excipients for its potential to bind or activate primary cells from multiple species (human, non-human primate, rodent)
  • We routinely perform immunophenotyping of in vitro or in vivo (safety, PD, xenograft, or clinical studies) treated samples (cell lines or primary cells)... Show more »
  • Evaluate your small molecule, biologic, or formulation excipients for its potential to bind or activate primary cells from multiple species (human, non-human primate, rodent)
  • We routinely perform immunophenotyping of in vitro or in vivo (safety, PD, xenograft, or clinical studies) treated samples (cell lines or primary cells) for specific protein target expression on cell subsets or biomarker detection indicative of bioactivity (cell surface activation markers, cytokine detection)
  • Personalized experimental design to ensure the most biologically relevant data is obtained
  • These assays are applicable to multiple species (human, non-human primates, & rodents) for cross-reactivity assessment of your molecules
  • All assays are performed with high-quality reagents and strict controls by experienced immunologists
Show less

ic

T Cell Activation and Proliferation Assays

Price on request

-Personalized experimental design to ensure the most biologically relevant data is obtained
-These assays are applicable to multiple species (human, non-human primates, & rodents) for cross-reactivity assessment of your molecules
-All assays are performed with high-quality reagents and strict controls by experienced... Show more »

-Personalized experimental design to ensure the most biologically relevant data is obtained
-These assays are applicable to multiple species (human, non-human primates, & rodents) for cross-reactivity assessment of your molecules
-All assays are performed with high-quality reagents and strict controls by experienced immunologists
-Assays include SEB Stimulation Assay, PHA Stimulation Assay, and CD3/CD28 Stimulation Assay

Show less

ic

Human Primary Cells

Price on request
Request a quote for more information about this service.

ic

Mixed Lymphocyte Reactions

Price on request
Request a quote for more information about this service.

ic

Immune Cell Assays

Price on request
Request a quote for more information about this service.

ic

Human Dendritic Cells

Price on request
Request a quote for more information about this service.

ic

Human B Cells

Price on request
Request a quote for more information about this service.

ic

Cytotoxicity Assays

Price on request
Request a quote for more information about this service.

ic

Cryostorage and Cryoprocessing

Price on request
Request a quote for more information about this service.

ic

Cryopreservation

Price on request
Request a quote for more information about this service.

ic

Contract Research

Price on request
Request a quote for more information about this service.

ic

Biospecimens

Price on request
Request a quote for more information about this service.

ic

Cells and Tissues

Price on request
Request a quote for more information about this service.

ic

Cytometry

Price on request
Request a quote for more information about this service.

ic

Cell-Based Assays

Price on request
Request a quote for more information about this service.

ic

Immunoassays

Price on request
Request a quote for more information about this service.

ic

Small Animal Toxicology Studies

Price on request
Request a quote for more information about this service.
Rabbit Mouse Rat Rodents

ic

Cell and Tissue Culture

Price on request

Cell and Tissue Culture Services

Cell and Tissue Culture Services

Show less

ic

Primary Cell Culture

Price on request
Request a quote for more information about this service.

ic

Natural Killer Cell Cytotoxicity Assay

Price on request
Request a quote for more information about this service.

ic

Phospho Flow Cytometry

Price on request
Request a quote for more information about this service.

ic

Assay Development

Price on request
Request a quote for more information about this service.

ic

Adherent Cell Cytometry

Price on request
Request a quote for more information about this service.

ic

Magnetic Activated Cell Sorting (MACS)

Magnetic activated cell sorting
Price on request
Request a quote for more information about this service.

ic

Biomarker Analysis

Price on request
Request a quote for more information about this service.

ic

Immunoglobulin Quantification

Price on request
Request a quote for more information about this service.

ic

Custom Immunoassay Development

Price on request
Request a quote for more information about this service.

ic

Cytokine Storm Testing

Price on request
Request a quote for more information about this service.

ic

Biology

Price on request
Request a quote for more information about this service.

ic

Bioanalytical Assays

Price on request

Bioanalytical Assays Services

Bioanalytical Assays Services

Show less

ic

Cytokine Analysis

Price on request
Request a quote for more information about this service.

ic

Flow Cytometry Data Analysis

Price on request
Request a quote for more information about this service.

ic

Animal Models and Studies

Price on request
Request a quote for more information about this service.

ic

Project Management

Price on request
Request a quote for more information about this service.

ic

Compound IC50 Assays

Price on request
Request a quote for more information about this service.

ic

Bioanalysis

Price on request
Request a quote for more information about this service.

ic

Drug Discovery & Development

Price on request

Drug Discovery & Development Services

Drug Discovery & Development Services

Show less

ic

Human Immune Cell Assays

Price on request
Request a quote for more information about this service.

ic

Fluorescence Activated Cell Sorting (FACS)

Fluorescence Activated Cell Sorting
Price on request
Request a quote for more information about this service.

ic

Toxicology

Price on request
Request a quote for more information about this service.

ic

In vivo Toxicity Testing

Price on request
Request a quote for more information about this service.

ic

Biomarkers

Price on request
Request a quote for more information about this service.

ic

Pharmacology & Toxicology

Price on request
Request a quote for more information about this service.

ic

In vitro Toxicity Testing

Price on request
Request a quote for more information about this service.

ic

Biospecimen Management and Storage

Price on request
Request a quote for more information about this service.

ic

Functional & Cell Type Specific Assays

Price on request
Request a quote for more information about this service.

ic

Human Biospecimens

Price on request
Request a quote for more information about this service.

Not finding what you're looking for?

Get info on this provider's capabilities without requesting a quote.
Missing Avatar

Chris Ng

Director

iQ Biosciences has not received any reviews.

iQ Biosciences has not received any endorsements.