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InTouch Bio

Moreno Valley California

Since 2008, InTouch BioSolutions LLC (www.intouchbio.com) has been providing quality contract services in preclinical drug discovery, research and development. Services are non-GLP.

InTouch Bio is committed to the proper care and use of animals in research. In addition to having an IACUC (institutional animal care and use committee), its 24/7 secured facility is approved by the California Department of Public Health to work exclusively with laboratory rats and mice.

In addition to preclinical in-vivo services, InTouch Bio provides a variety of other services. These include biomarker development and validation, cell-based assays, cell isolation/differentiation and flow cytometry analysis and high-speed cell separation by fluorescence-activated cell sorting (FACS) services.

InTouch Bio has not listed any services.

Mast Cell Degranulation
Price on request

In-vitro mast cell degranulation assay (96-well format) using peritoneal lavage cells as source of mast cells from rat or mouse.

In-vitro mast cell degranulation assay (96-well format) using peritoneal lavage cells as source of mast cells from rat or mouse.

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Mouse
Rat
T cell proliferation assays
Price on request

Human or mouse T cell proliferation assays. Activators: anti-CD3 +/- anti-CD28 in soluble or plate-bound format; Anti-CD3 coated beads. 96-well format.

Human or mouse T cell proliferation assays. Activators: anti-CD3 +/- anti-CD28 in soluble or plate-bound format; Anti-CD3 coated beads. 96-well format.

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Human
Mouse
Rat
In vivo T-cell activation assay
Price on request

Our DO11 in-vivo T-cell activation model is a robust mouse model that is relatively quick (3 days) and amenable for evaluation of compounds in-vivo to assess drug effect on T-cell and antigen presenting cell (e.g., dendritic cells) functions. DO11 transgenic mice express the ovalbumin-specific T-cell receptor. Treated mice receive... Show more »

Our DO11 in-vivo T-cell activation model is a robust mouse model that is relatively quick (3 days) and amenable for evaluation of compounds in-vivo to assess drug effect on T-cell and antigen presenting cell (e.g., dendritic cells) functions. DO11 transgenic mice express the ovalbumin-specific T-cell receptor. Treated mice receive a bolus of ovalbumin protein/peptide injection and plasma cytokine levels are monitored over time. The model is ideal for determining compound MOA or confirming proposed MOA targeting T-cells and/or antigen presenting cells. This service is IACUC supported to ensure proper care and use of animals in research.

The above model is also useful in in-vitro settings to evaluate compound effects for higher throughput.

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Mouse
B Cell Activation Assay
Price on request

Human or mouse B-cell activation assays. Activators: anti-IgM, anti-CD40, LPS.

Human or mouse B-cell activation assays. Activators: anti-IgM, anti-CD40, LPS.

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Cell Migration assay
Price on request

High-throughput 96-well format

High-throughput 96-well format

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Human
Mouse
Cell Proliferation assays
Price on request

High-throughput 96-well format. Brd-U incorporation assessed by Brd-U ELISA. MTS (modified MTT method).

High-throughput 96-well format. Brd-U incorporation assessed by Brd-U ELISA. MTS (modified MTT method).

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Human
Mouse
Rat
Cell viability assay
Price on request

High-throughput 96-well format (colorimetric or fluorescence based). Flow cytometry analysis is also available.

High-throughput 96-well format (colorimetric or fluorescence based). Flow cytometry analysis is also available.

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Human
Mouse
Rat
Cells and Tissues
Price on request

Cells and tissues are provided fresh or frozen. Courier same day delivery available to Los Angeles, San Diego area. Otherwise, FedEx next day AM air service is the alternative delivery method.

Human (cells are derived from normal healthy blood donors).
1. PBMCs
2. Whole blood (in EDTA lavender collection tube)

Rat or... Show more »

Cells and tissues are provided fresh or frozen. Courier same day delivery available to Los Angeles, San Diego area. Otherwise, FedEx next day AM air service is the alternative delivery method.

Human (cells are derived from normal healthy blood donors).
1. PBMCs
2. Whole blood (in EDTA lavender collection tube)

Rat or Mouse
1. Whole blood (in EDTA)
2. Splenocytes
3. Organs (as per request)
4. Tissues (as per reques)

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Human
Mouse
Rat
Cytotoxicity assay
Price on request

High-throughput 96-well format (colorimetric or fluorescence based). Flow cytometry analysis is also available.

High-throughput 96-well format (colorimetric or fluorescence based). Flow cytometry analysis is also available.

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Human
Mouse
Rat
Mouse Dendritic Cells
Price on request

Blood derived (magnetically purified) or Bone-marrow differentiated Dendritic Cells. Purity analysis by flow cytometry.

Blood derived (magnetically purified) or Bone-marrow differentiated Dendritic Cells. Purity analysis by flow cytometry.

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Mouse
Human Dendritic Cells
Price on request

Blood derived (magnetically purified) or monocyte differentiated dendritic cells. Purity analysis by flow cytometry.

Blood derived (magnetically purified) or monocyte differentiated dendritic cells. Purity analysis by flow cytometry.

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Human
Superior Cervical Ganglia
Price on request

Purified primary sympathetic neurons from superior cervical ganglia (SCG) of newborn (PO-P1) rat pups

Purified primary sympathetic neurons from superior cervical ganglia (SCG) of newborn (PO-P1) rat pups

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Mouse Kupffer Cells
Price on request

Kupffer Cells from mouse liver. Enzymatically dissociated and magnetically purified. Validation by flow cytometry.

Kupffer Cells from mouse liver. Enzymatically dissociated and magnetically purified. Validation by flow cytometry.

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Primary Cell Isolation
Price on request

Magnetic-based purification and/or cell sorting (FACS). Freshly purified cells from blood or tissues from human, rat and mouse. Cells from tissues e.g., spleen, liver, heart, lungs, neural tissues, tumors, brain, thymus and lymph nodes are isolated using an automated dissociator employing gentle preparation of single cells.... Show more »

Magnetic-based purification and/or cell sorting (FACS). Freshly purified cells from blood or tissues from human, rat and mouse. Cells from tissues e.g., spleen, liver, heart, lungs, neural tissues, tumors, brain, thymus and lymph nodes are isolated using an automated dissociator employing gentle preparation of single cells. Sterile sample handling, same day isolation and delivery are available at request.

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Xenograft studies
Price on request

Xenograft subcutaneous tumor models in immunodeficient mice (e.g., SCID, Nude)

Our 24/7 secured facility is attended by a skilled staff with many years of experience in proper handling of research animals. We are committed to the proper care and use of animals in research. In addition to having an IACUC (institutional animal... Show more »

Xenograft subcutaneous tumor models in immunodeficient mice (e.g., SCID, Nude)

Our 24/7 secured facility is attended by a skilled staff with many years of experience in proper handling of research animals. We are committed to the proper care and use of animals in research. In addition to having an IACUC (institutional animal care and use committee), we are approved by the California Department of Public Health to work exclusively with laboratory rats and mice.

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Cell Based Assays Consulting
Price on request

High-throughput 96-well format

Cell proliferation, viability or migration assays
Cell activation, stimulation or co-culture assays
Flow cytometry (FACS) based assays

High-throughput 96-well format

Cell proliferation, viability or migration assays
Cell activation, stimulation or co-culture assays
Flow cytometry (FACS) based assays

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In vivo efficacy
Price on request

Our 24/7 secured facility is attended by a skilled staff with many years of experience in proper handling of research animals. We are committed to the proper care and use of animals in research. In addition to having an IACUC (institutional animal care and use committee), we are approved by the California Department of Public... Show more »

Our 24/7 secured facility is attended by a skilled staff with many years of experience in proper handling of research animals. We are committed to the proper care and use of animals in research. In addition to having an IACUC (institutional animal care and use committee), we are approved by the California Department of Public Health to work exclusively with laboratory rats and mice.

Please contact us for additional information on:
1) Mouse cancer models (syngeneic and xenograft tumor models)
2) Inflammation disease models (e.g., mouse CIA [collagen-induced arthritis model])
3) Obesity mouse model
4) And others.

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Obesity animal model
Price on request

Diet-induced obese (DIO) mouse model. Summary: C57BL/6 obese mice are allowed to acclimate over a period of 2 weeks while on a high-fat diet and enrolled into treatment groups when body weights stabilize and/or exhibit an upward trend. Mice are kept on a high-fat diet during treatment and weight recorded. Treatment route will vary... Show more »

Diet-induced obese (DIO) mouse model. Summary: C57BL/6 obese mice are allowed to acclimate over a period of 2 weeks while on a high-fat diet and enrolled into treatment groups when body weights stabilize and/or exhibit an upward trend. Mice are kept on a high-fat diet during treatment and weight recorded. Treatment route will vary as per client request. Terminal procedures performed (e.g., blood (plasma) collection, tissue harvest) will vary as per client request. This service is IACUC supported to ensure proper care and use of animals in research.

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Mouse
Rheumatoid arthritis animal model
Price on request

Our mouse collagen-induced arthritis (cia) is a robust and reliable model for efficacy testing of compounds. Male or female DBA/1 mice are immunized with type II collagen emulsified in Complete Freund's Adjuvant (CFA) (Day 1-20) and with type II collagen emulsified in Incomplete Freund's Adjuvant (IFA) three weeks later... Show more »

Our mouse collagen-induced arthritis (cia) is a robust and reliable model for efficacy testing of compounds. Male or female DBA/1 mice are immunized with type II collagen emulsified in Complete Freund's Adjuvant (CFA) (Day 1-20) and with type II collagen emulsified in Incomplete Freund's Adjuvant (IFA) three weeks later (Day 21). Prophylactic, semi-therapeutic or therapeutic treatment may be administered by oral gavage, intravenous injection, subcutaneous, intraperitoneal injection and/or implant with an osmotic pump. Controls available inlcude: anti-TNF biologics and/or dexamethasone. Clinical scores include a) Paw scores, b) Hind-paw thickness and c) Body weight. Independent histopathological analysis of joints is available at request and provided by a certified pathologist. This service is IACUC supported to ensure proper care and use of animals in research.

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Mouse
Isolation of peritoneal cells
Price on request

Obtain freshly isolated peritoneal cells from rat and mice by lavage method. Cost of animals are separate and based on cost associated with vendor price and necessary housing/husbandry.

Obtain freshly isolated peritoneal cells from rat and mice by lavage method. Cost of animals are separate and based on cost associated with vendor price and necessary housing/husbandry.

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Mouse
Rat
Organ harvesting
Price on request

Fresh cells, tissues and organs harvest

Fresh cells, tissues and organs harvest

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Mouse
Rat
Cytokine quantitation
Price on request

We provide cytokine quantification by ELISA, EIA or flow cytometry (e.g., intracellular).

We provide cytokine quantification by ELISA, EIA or flow cytometry (e.g., intracellular).

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Chicken
Goat
Human
Mouse
Porcine
Rabbit
Rat
Vaccine production
Price on request

Vaccine development in mice (cellular & antibody response)

Vaccine development in mice (cellular & antibody response)

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Mouse
Rat
Product testing
Price on request

We employ industry-standard cell assay and cell isolation technology with many years of cell-based assay experience to provide independent/unbiased validation and testing of life science products for use in cell-based assays and related applications. Services are non-GLP/GMP and offer a cost-effective step toward GLP/GMP testing.... Show more »

We employ industry-standard cell assay and cell isolation technology with many years of cell-based assay experience to provide independent/unbiased validation and testing of life science products for use in cell-based assays and related applications. Services are non-GLP/GMP and offer a cost-effective step toward GLP/GMP testing. Services come with its exclusive warranty of repeat service or money-back guarantee.

Service Includes (not limited to):
- Confidential and rapid initiation
- Testing in custom or standard cell assays
- Side-by-side comparison with standard control
- Independent review by expert consultant (option)
- Comprehensive study report and post-study support

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Custom Assay Development
Price on request

High-throughput 96-well format

  • Cell proliferation, viability or migration assays
  • Cell activation, stimulation or co-culture assays
  • Flow cytometry (FACS) based assays

High-throughput 96-well format

  • Cell proliferation, viability or migration assays
  • Cell activation, stimulation or co-culture assays
  • Flow cytometry (FACS) based assays
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Immunogenicity assay (in vivo)
Price on request
  • Immunogenicity testing of therapeutic proteins in pre- or clinical samples in mice and rats assessing cellular & antibody immune responses.
  • Immunogenicity testing of therapeutic proteins in pre- or clinical samples in mice and rats assessing cellular & antibody immune responses.
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Mouse
Rat
Flow cytometry
Price on request

Our flow cytometry services offer cellular analysis and high-speed cell separation by fluorescence-activated cell sorting (FACS) enhanced by magnetic bead-based pre-isolation to insure purity and high efficiency. Same day pickup/delivery is available to Los Angeles, San Diego, and Inland Empire customers.

Our flow cytometry services offer cellular analysis and high-speed cell separation by fluorescence-activated cell sorting (FACS) enhanced by magnetic bead-based pre-isolation to insure purity and high efficiency. Same day pickup/delivery is available to Los Angeles, San Diego, and Inland Empire customers.

  • Intracellular and surface marker analysis
  • 4-color parameter & cell-cycle analysis
  • Cell sorting by BD FACSAria (opt: sterile sort)
  • Pre-diagnostic clinical evaluation (non-CLIA)
  • Rapid initiation and confidential
  • Most BSL-1 samples accepted
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Human
Mouse
Rat
ELISA
Enzyme-linked immunosorbent assay
Price on request

High-throughput 96-well format analyte measurements

High-throughput 96-well format analyte measurements

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