Integrity BioSolutions

If there's a process instrument (pH, EC, DO, turbidity, etc...) that you'd like and couldn't afford, please contact me. It is likely that I can build one that is way cheaper than what you can get from the major vendors.

We can express and purify monoclonal antibodies at 50-250 mg scale. High purity with extremely low endotoxin content. We can also reformat antibodies (i.e., isotype modification) for your needs. In addition we can provide polyclonal antibody development and custom purification. All in vivo, expression and purification work done in San Diego, USA. Please contact for quote.

We can provide low-cost and customized lab equipment for measuring pH and conductivity. By using modern microcontroller hardware and our proprietary software, we can provide a variety of instruments for research or bioprocess applications. For instance, our pH meter (the pipSqueak pH) has resolution better than 0.001 pH unit, USB and Bluetooth connectivity, automatic temperature compensation, and compatibility with all major electrodes for $150!!! Compare this to entry-level meters from the major scientific supply companies that start in the $850-$1000 range. We also offer conductivity and dissolved oxygen meters and prices far below our competitors. Developed and built in San Diego, CA USA.

We have developed proprietary reagents to activate B-cells in rodents in vivo or in whole blood. Using a novel anti-IgD reagent, we can test the effects of B-cell activation inhibitors rapidly in rodent model systems. We routinely get > 35% CD86+ B-cells in vivo with 3 hours for administration! Please email for protocols, quotes for reagents, or requests for CRO work.

Integrity BioSolutions can provide animal albumins for in vivo work, particularly for nanoparticle drug development. We custom manufacture mouse and rat albumin at >98% purity (HPLC) in standard clinical formulations. We have proprietary methods to generate 1-200 gram quantities of albumins with ultra-low endotoxin and polymer contamination at prices far below those of the standard biochemical suppliers. We supply in standard formulations (such as those used clinically in humans and for manufacturing pharmaceutical albumin conjugates). Tiered pricing for large quantities. If you require rodent albumins for use in immunocompetent models (i.e., for immune checkpoint studies), please contact us!