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Inimmune Corp.

Missoula, Montana, US

Inimmue is a promising new biotechnology company founded by pharmaceutical industry veterans, focused on developing the next generation of immunotherapeutics. The group has extensive expertise in synthetic and process chemistry, drug formulation and immunology. Our pipeline currently includes several compounds and formulations thereof that modulate the innate immune system through Toll-like Receptors 4 and 7/8. Current preclinical programs are developing these assets for use in areas of critical patient need such as food allergy, allergic rhinitis, autoimmunity, as well as topically in cancer. Additionally, Inimmune applies its collective 50 years of expertise in preclinical drug development to offer various contract services.

Inimmune was founded in early 2016 by Drs. Jay Evans, David Burkhart, Helene Bazin-Lee, Kendal Ryter and a team of 11 highly trained scientists. It is located in Missoula, MT and works in... Show more »

Inimmue is a promising new biotechnology company founded by pharmaceutical industry veterans, focused on developing the next generation of immunotherapeutics. The group has extensive expertise in synthetic and process chemistry, drug formulation and immunology. Our pipeline currently includes several compounds and formulations thereof that modulate the innate immune system through Toll-like Receptors 4 and 7/8. Current preclinical programs are developing these assets for use in areas of critical patient need such as food allergy, allergic rhinitis, autoimmunity, as well as topically in cancer. Additionally, Inimmune applies its collective 50 years of expertise in preclinical drug development to offer various contract services.

Inimmune was founded in early 2016 by Drs. Jay Evans, David Burkhart, Helene Bazin-Lee, Kendal Ryter and a team of 11 highly trained scientists. It is located in Missoula, MT and works in close collaboration with the Center for Translational Medicine at the University of Montana as well as several industry and academia partners.

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Biochemistry & Molecular Biology
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Compound Library Design
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Immunology Animal Models
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Inimmune employs technical experts in both in vitro and in vivo analysis of immune modulation. Our staff have extensive technical expertise in all facets of immunological analysis including but not limited to: intracellular cytokine staining and FACS analysis, primary human cell isolation, culture and analysis, ELISA/Luminex... Show more »

Inimmune employs technical experts in both in vitro and in vivo analysis of immune modulation. Our staff have extensive technical expertise in all facets of immunological analysis including but not limited to: intracellular cytokine staining and FACS analysis, primary human cell isolation, culture and analysis, ELISA/Luminex analysis, cell-based screening assays for transcription factor activation and/or cytokine production, affinity measurements of both monoclonal and polyclonal antibody serum and various in vivo animal models. Contact us for consultation designing experimental set ups or developing and executing specialized assays or in vivo immunological studies.

Immunology experience and capabilities Include but are not limited to:

  • In vitro compound screening
  • Cell-based potency assays
  • Octet Red-based affinity measurements (mono- and polyclonal antibody sera, protein:protein, protein:ligand)
  • In vivo mouse animal studies (expertise in flu vaccination and challenge models and several cancer models)
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Compound Synthesis
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Clinical Immunology Tests
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Inimmune employs technical experts in both in vitro and in vivo analysis of immune modulation. Our staff have extensive technical expertise in all facets of immunological analysis including but not limited to: intracellular cytokine staining and FACS analysis, primary human cell isolation, culture and analysis, ELISA/Luminex... Show more »

Inimmune employs technical experts in both in vitro and in vivo analysis of immune modulation. Our staff have extensive technical expertise in all facets of immunological analysis including but not limited to: intracellular cytokine staining and FACS analysis, primary human cell isolation, culture and analysis, ELISA/Luminex analysis, cell-based screening assays for transcription factor activation and/or cytokine production, affinity measurements of both monoclonal and polyclonal antibody serum and various in vivo animal models. Contact us for consultation designing experimental set ups or developing and executing specialized assays or in vivo immunological studies.

Immunology experience and capabilities Include but are not limited to:

  • In vitro compound screening
  • Cell-based potency assays
  • Octet Red-based affinity measurements (mono- and polyclonal antibody sera, protein:protein, protein:ligand)
  • In vivo mouse animal studies (expertise in flu vaccination and challenge models and several cancer models)
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Cell-Based Compound Screening
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Drug Potency and Efficacy Testing
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Flow Cytometry
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Intracellular Cytokine Staining
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FACS
Fluorescence Activated Cell Sorting
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Antibody Affinity Maturation
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Drug Mechanism of Action Studies
Mechanism of Action Studies
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Preclinical Efficacy Studies
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Analytical Chemistry Services
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The Inimmune team has over 40 years of combined analytical chemistry experience in the pharmaceutical industry ranging from small molecules to peptides. Whether your need is an HPLC method for quantitation and identity in a complex formulation or a high sensitivity MS method to detect an API in a biological matrix, Inimmune can... Show more »

The Inimmune team has over 40 years of combined analytical chemistry experience in the pharmaceutical industry ranging from small molecules to peptides. Whether your need is an HPLC method for quantitation and identity in a complex formulation or a high sensitivity MS method to detect an API in a biological matrix, Inimmune can provide solutions.

Analytical chemistry experience and capabilities Include but are not limited to:

  • RP-HPLC
  • SEC-HPLC
  • DLS
  • LC-MS
  • MALDI-TOF MS
  • DSC
  • SDS-PAGE
  • BCA
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Product Stability Testing
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Assay Development Consulting
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Osmolality Measurement
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RP-HPLC
Reversed Phase high-performance liquid chromatography
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HPLC
High Performance Liquid Chromatography
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Dynamic Light Scattering
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MALDI TOF MS
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
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PAGE
Polyacrylamide Gel Electrophoresis
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Isoelectric Focusing (IEF)
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NMR
Nuclear magnetic resonance spectroscopy
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LC-MS
Liquid Chromatography-Coupled Mass Spectrometry
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Pharmaceutical Formulation
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History has shown that drug formulation can have a substantial impact on nearly every quality characteristic of an API including potency, bioavailability, solubility, dosage, route of administration and stability. Inimmune offers parenteral drug formulation R&D services for early stage and preclinical candidates with a special... Show more »

History has shown that drug formulation can have a substantial impact on nearly every quality characteristic of an API including potency, bioavailability, solubility, dosage, route of administration and stability. Inimmune offers parenteral drug formulation R&D services for early stage and preclinical candidates with a special emphasis in nanoparticle based drug delivery technology. Our formulation team has over 40 years of combined experience in API formulation and associated analytical method development with a particular focus on vaccines and immunotherapeutics. The Inimmune team can help you troubleshoot existing formulations issues or develop novel formulations suited for your application and business need.

Formulations experience and capabilities include but are not limited to:

  • Salt screening
  • Co-Solvent studies
  • Liposomes
  • Block copolymers (such as PLGA)
  • Nanoemulsions
  • Solid Lipid Nanoparticles (SLNs)
  • Alum based formulations
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Particle Size Distribution
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Drug Delivery Systems
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Nanoparticle drug delivery systems (liposomes, block copolymers, emulsions, SLNs, etc)

Nanoparticle drug delivery systems (liposomes, block copolymers, emulsions, SLNs, etc)

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Lyophilization
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Chemical Crosslinking/Bioconjugation
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Salt Screening
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Synthetic Chemistry
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Inimmune’s synthetic medicinal chemists have expertise in molecule generation, purification, process scale-up, characterization and molecular optimization through data driven structure-activity-relationship (SAR) studies. Equipped with state-of-the-art synthesis tools our chemistry team can produce a range of batch sizes... Show more »

Inimmune’s synthetic medicinal chemists have expertise in molecule generation, purification, process scale-up, characterization and molecular optimization through data driven structure-activity-relationship (SAR) studies. Equipped with state-of-the-art synthesis tools our chemistry team can produce a range of batch sizes (non-cGMP) and customize the synthetic process to meet your business needs.

Synthetic & medicinal chemistry experience and capabilities Include but are not limited to:

  • Heterocycle synthesis
  • Asymmetric synthesis
  • Carbohydrates
  • Lipids and Phospholipids
  • Process optimization
  • Process scale-up
  • Green chemistry method development
  • Bioconjugation
  • Linker Chemistry
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Compound Library Synthesis
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Categorical Structure Activity Relationship Modeling
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Solubility and Dissolution Testing
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Scale-up Production
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Carbohydrate Services
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Lipids/Phospholipids
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Retrosynthetic Analysis and Synthetic Route Design
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Synthetic route optimization

Synthetic route optimization

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Hit Identification
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Electrophoresis
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Computational Modeling
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Pharmacology & Toxicology
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Material Testing Services
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Antibody Services
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Mass Spectrometry
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Medicinal Chemistry
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Chromatography
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Cytometry
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Spectroscopy
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MALDI Mass Spectrometry Methods
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Cells and Tissues
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Clinical Research
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Protein Conjugation
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Clinical Laboratory Services
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DNA Services
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Purification Services
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Formulation Services
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DNA Libraries
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Clinical Chemistry
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Project and Process Management
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Liquid Chromatography
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Process Consulting
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Drug Discovery
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Protein Services
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Gel Electrophoresis
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Experimental Design
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Chemistry and Materials
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Drug Development
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Animal Models and Studies
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Immunoassays
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Scattering Techniques
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Engineering and Fabrication
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Liquid Chromatography Coupled Mass Spectrometry Methods
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Animal Models of Disease
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Product Development, Testing, and Packaging
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Biology
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Nucleic Acid Services
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Drug Discovery & Development
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Imaging & Spectroscopy
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Physical Analysis Methods
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Mammalian Cell Culture
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Compound Libraries
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Compound Libraries Services

Compound Libraries Services

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