Immune Biosolutions focuses on the discovery of new therapeutic antibodies against conserved targets in mammals. The platform includes several screening technologies such as phage display or single cells. The platform specializes in the discovery of chicken antibodies, but also antibodies derived from other species if requested. All discovery projects are done in partnership.
Immune Biosolutions also has a service sub-division to help companies in their discovery process.
The services include the distribution of research antibodies via sunshineantibodies.com and also several other services described on the storefront. The personalized approach is favored for each client project.
To meet your specific needs and expectations, our antibody development process consists of 4 phases under strict confidentiality:
1- Designing a variety of antigens to address difficult proteins.
Unique antigen strategies including Spatial Peptides that are rationally designed and functionality-oriented synthetic 3D peptides that mimic native structure of challenging targets
2-Generating antibody diversity
Based on the chicken immune system: in vivo titer maturation, new epitopes, species cross-reactive abs…
Not limited by immunological tolerance: high success rate with mammalian conserved proteins
3-Selecting the best binders.
Efficient ex vivo phage-display selection coupled with NGS to explore the full diversity of chicken ab libraries
4-Formatting recombinant antibody for specific applications.
Highly successful formatting workflow with a variety of recombinant format to choose from. Validated human frameworks with ultra-low immunogenicity profiles for therapeutic applications available.
To meet your specific needs and expectations, our antibody development process consists of 3 phases under strict confidentiality:
DLS analysis of protein samples
Full characterization of protein using DSF
(Tm, Tagg, sizing, polydispersity, isothermal stability, viscosity, etc.)
Full characterization of antibody mode of action using a bioluminescent reporter cell line or fresh PBMC
Deep expertise in T cell stimulation and proliferation assay (Treg, Teff). The project will be built upon client request
We offer all type of custom bioconjugaison for a competitive price.
Immune Biosolutions has not received any reviews.
Immune Biosolutions has not received any endorsements.