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Immune Biosolutions

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Sherbrooke, Quebec, CA

About Immune Biosolutions

Immune Biosolutions focuses on the discovery of new therapeutic antibodies against conserved targets in mammals. The platform includes several screening technologies such as phage display or single cells. The platform specializes in the discovery of chicken antibodies, but also antibodies derived from other species if requested. All discovery projects are done in partnership.

Immune Biosolutions also has a service sub-division to help companies in their discovery process.

The services include the distribution of research antibodies via sunshineantibodies.com and also several other services described on the storefront. The personalized approach is favored for each client project.

Our Services (14)


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Recombinant Antibody Production

Price on request

To meet your specific needs and expectations, our antibody development process consists of 4 phases under strict confidentiality:
1- Designing a variety of antigens to address difficult proteins.
Unique antigen strategies including Spatial Peptides that are rationally designed and functionality-oriented synthetic 3D peptides that mimic native structure of challenging targets
2-Generating antibody diversity
Based on the chicken immune system: in vivo titer maturation, new epitopes, species cross-reactive abs…
Not limited by immunological tolerance: high success rate with mammalian conserved proteins
3-Selecting the best binders.
Efficient ex vivo phage-display selection coupled with NGS to explore the full diversity of chicken ab libraries
4-Formatting recombinant antibody for specific applications.
Highly successful formatting workflow with a variety of recombinant format to choose from. Validated human frameworks with ultra-low immunogenicity profiles for therapeutic applications available.

Inflammation Inflammatory Bowel Disease Drug Discovery phage display NGS ultra-humanization Gastric Cancer G-protein Ion Channel membrane protein Infectious Disease Oncology Show 12 more tags Show less

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Polyclonal Antibody Production

Price on request

To meet your specific needs and expectations, our antibody development process consists of 3 phases under strict confidentiality:

  1. Design: We gather antibody requirements, evaluate the feasibility and submit a customized proposal that defines our peptide selection, timelines and cost.
  • Generation: Following the design’s approval, the peptide (or other target molecule) is synthesized. We start with a 60-day immunization program with constant antibody titer monitoring.
  • Validation +: We validate the antibody by ELISA (we guarantee positive ELISA against the immunizing peptide) and Western blot (when possible). Depending on the project, an affinity purification and direct coupling may be required. A complete technical report is delivered with generation details and suggested concentration of antibodies for the most common applications.

Chicken Drug Discovery Biology Antibody Production immunization Oncology Infectious Disease Inflammation Show 8 more tags Show less

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Dynamic Light Scattering

Starting at $150.00 per sample

DLS analysis of protein samples


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Differential Scanning Fluorimetry (DSF)

Differential Scanning Fluorimetry
Starting at $400.00 per sample

Full characterization of protein using DSF

(Tm, Tagg, sizing, polydispersity, isothermal stability, viscosity, etc.)


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ADCC and CDC Assays

Price on request

Full characterization of antibody mode of action using a bioluminescent reporter cell line or fresh PBMC

 

 


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T Cell Activation and Proliferation Assays

Price on request

Deep expertise in T cell stimulation and proliferation assay (Treg, Teff). The project will be built upon client request


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Bioconjugation/Chemical Crosslinking

Price on request

We offer all type of custom bioconjugaison for a competitive price.


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Antibody Purification

Price on request
Request a quote for more information about this service.

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Protein Expression Visualization

Price on request
Request a quote for more information about this service.

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Immunostaining

Price on request
Request a quote for more information about this service.

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Biochemistry & Molecular Biology

Price on request
Request a quote for more information about this service.

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Immunocytochemistry

Price on request
Request a quote for more information about this service.

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Immunohistochemistry (IHC)

Price on request
Request a quote for more information about this service.

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Fluorescence Activated Cell Sorting (FACS)

Fluorescence Activated Cell Sorting
Price on request
Request a quote for more information about this service.

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Simon Gaudreau

Chief Scientific Officer

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